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Studies from L.E. Simental-Mendia et al Provide New Data on Vitamin E Deficiency (Vitamin E Deficiency and Oxidative Status are Associated with...

Health & Medicine Week

10-20-17

Studies from L.E. Simental-Mendia et al Provide New Data on Vitamin E Deficiency (Vitamin E Deficiency and Oxidative Status are Associated with Prediabetes in Apparently Healthy Subjects)

By a News Reporter-Staff News Editor at Health & Medicine Week -- Fresh data on Nutritional and Metabolic Diseases and Conditions - Vitamin E Deficiency are presented in a new report. According to news reporting originating from Durango, Mexico, by NewsRx correspondents, research stated, "Previous studies have indicated that vitamin E deficiency and oxidative stress affect the beta cell function. Hence, the aim of this study was to determine the association between vitamin E deficiency and oxidative status with prediabetes in apparently healthy subjects."

Our news editors obtained a quote from the research, "Apparently healthy men and women aged 18-65 years were enrolled in a case control study. Individuals with new diagnosis of prediabetes were considered as cases and compared with a control group of individuals with normal glucose tolerance. Smoking, alcohol intake, pregnancy, diabetes, kidney disease, liver disease, cardiovascular disease, malignancy, glucocorticoid treatment and consumption of lipid-lowering drugs, antioxidants and vitamin supplements were exclusion criteria. Vitamin E deficiency was defined by serum levels of alpha-tocopherol < 11.6 mu mol/L, oxidative status was assessed by total antioxidant capacity and lipid peroxidation, and prediabetes was considered by the presence of impaired fasting glucose and/or impaired glucose tolerance. A total of 148 subjects were allocated into the case (n = 74) and control (n = 74) groups. The frequency of vitamin E deficiency was higher in the case group (41.8%) compared with the control group (35.1%), p = 0.03. The logistic regression analysis adjusted by age, waist circumference and body mass index, revealed a significant association between vitamin E deficiency (OR 3.23; 95% CI: 1.34-7.79, p = 0.009), lipoperoxidation (OR 2.82; CI 95%: 1.42-5.59, p = 0.003) and total antioxidant capacity (OR 0.93; CI 95%: 0.90-0.96, p< 0.001) with prediabetes."

According to the news editors, the research concluded: "Results of the present study suggest that both vitamin E deficiency and oxidative status are associated with prediabetes in apparently healthy subjects."

For more information on this research see: Vitamin E Deficiency and Oxidative Status are Associated with Prediabetes in Apparently Healthy Subjects. Archives of Medical Research, 2017;48(3):257-262. Archives of Medical Research can be contacted at: Elsevier Science Inc, 360 Park Ave South, New York, NY 10010-1710, USA. (Elsevier - www.elsevier.com; Archives of Medical Research - www.journals.elsevier.com/archives-of-medical-research/)

The news editors report that additional information may be obtained by contacting L.E. Simental-Mendia, Inst Mexicano Seguro Social Durango, Unidad Invest Biomed, Durango, Dgo, Mexico. Additional authors for this research include G. Rodriguez-Ramirez, M.D. Carrera-Gracia and M.A. Quintanar-Escorza (see also Nutritional and Metabolic Diseases and Conditions - Vitamin E Deficiency).

The direct object identifier (DOI) for that additional information is: https://doi.org/10.1016/j.arcmed.2017.03.018. This DOI is a link to an online electronic document that is either free or for purchase, and can be your direct source for a journal article and its citation.

Keywords for this news article include: Durango, Mexico, North and Central America, Nutritional and Metabolic Diseases and Conditions, Deficiency Diseases and Conditions, Vitamin E Deficiency, Nutrition Disorders, Malnutrition, Avitaminosis.

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