Findings from P. Govitrapong et al Update Understanding of Melatonin Therapy (Melatonin as a mitochondrial protector in neurodegenerative diseases)

By a News Reporter-Staff News Editor at Drug Week -- Investigators discuss new findings in Drugs and Therapies - Melatonin Therapy. According to news reporting from Bangkok, Thailand, by NewsRx journalists, research stated, "Mitochondria are crucial organelles as their role in cellular energy production of eukaryotes. Because the brain cells demand high energy for maintaining their normal activities, disturbances in mitochondrial physiology may lead to neuropathological events underlying neurodegenerative conditions such as Alzheimer's disease, Parkinson's disease and Huntington's disease."

The news correspondents obtained a quote from the research, "Melatonin is an endogenous compound with a variety of physiological roles. In addition, it possesses potent antioxidant properties which effectively play protective roles in several pathological conditions. Several lines of evidence also reveal roles of melatonin in mitochondrial protection, which could prevent development and progression of neurodegeneration. Since the mitochondrial dysfunction is a primary event in neurodegeneration, the neuroprotection afforded by melatonin is thereby more effective in early stages of the diseases."

According to the news reporters, the research concluded: "This article reviews mechanisms which melatonin exerts its protective roles on mitochondria as a potential therapeutic strategy against neurodegenerative disorders."

For more information on this research see: Melatonin as a mitochondrial protector in neurodegenerative diseases. Cellular and Molecular Life Sciences, 2017;74(21):3999-4014. Cellular and Molecular Life Sciences can be contacted at: Springer Basel Ag, Picassoplatz 4, Basel, 4052, Switzerland. (Springer - www.springer.com; Cellular and Molecular Life Sciences - www.springerlink.com/content/1420-682x/)

Our news journalists report that additional information may be obtained by contacting P. Govitrapong, Chulabhorn Royal Academy, Chulabhorn Grad Inst, Bangkok 10210, Thailand (see also Drugs and Therapies - Melatonin Therapy).

The direct object identifier (DOI) for that additional information is: https://doi.org/10.1007/s00018-017-2614-x. This DOI is a link to an online electronic document that is either free or for purchase, and can be your direct source for a journal article and its citation.

Keywords for this news article include: Bangkok, Thailand, Asia, Drugs and Therapies, Article Review, Free Radical Scavenger, Melatonin Therapy, Anticonvulsants, Antioxidants, Hormones, Adjuvant.

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