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Researchers from University of Perugia Describe Findings in Alzheimer Disease (Vitamin E family: Role in the pathogenesis and treatment of...

Clinical Trials Week

11-03-17

Researchers from University of Perugia Describe Findings in Alzheimer Disease (Vitamin E family: Role in the pathogenesis and treatment of Alzheimer's disease)

By a News Reporter-Staff News Editor at Clinical Trials Week -- Investigators publish new report on Neurodegenerative Diseases and Conditions - Alzheimer Disease. According to news reporting originating in Perugia, Italy, by NewsRx journalists, research stated, "Vitamin E family, composed by tocopherols and tocotrienols, is a group of compounds with neuroprotective properties. The exact role in the pathogenesis and the benefit of vitamin E as treatment for Alzheimer's disease (AD) are still under debate."

The news reporters obtained a quote from the research from the University of Perugia, "A literature search in PubMed, Medline, and Cochrane databases has been carried out. All types of studies, from bench and animal models to clinical, were included. High plasma vitamin E levels are associated with better cognitive performance, even if clear evidence of their ability to prevent or delay cognitive decline in AD is still lacking. Each vitamin E form is functionally unique and shows specific biological functions. Tocotrienols seem to have superior antioxidant and anti-inflammatory properties compared with tocopherols."

According to the news reporters, the research concluded: "The benefit of vitamin E as a treatment for AD is still under debate, mainly because of?the inconsistent findings from observational studies and the methodological limitations of clinical trials."

For more information on this research see: Vitamin E family: Role in the pathogenesis and treatment of Alzheimer's disease. Alzheimer's & Dementia, 2016;2(3):182-191. (Elsevier - www.elsevier.com; Alzheimer's & Dementia - www.journals.elsevier.com/alzheimers-and-dementia/)

Our news correspondents report that additional information may be obtained by contacting V. Boccardi, Dept. of Medicine, Institute of Gerontology and Geriatrics, University of Perugia, Perugia, Italy. Additional authors for this research include M. Baroni, F. Mangialasche and P. Mecocci (see also Neurodegenerative Diseases and Conditions - Alzheimer Disease).

The direct object identifier (DOI) for that additional information is: http://dx.doi.org/10.1016/j.trci.2016.08.002. This DOI is a link to an online electronic document that is either free or for purchase, and can be your direct source for a journal article and its citation.

Keywords for this news article include: Italy, Europe, Perugia, Dementia, Vitamin E, Tauopathies, Article Review, Alzheimer Disease, Brain Diseases and Conditions, Neurodegenerative Diseases and Conditions, Central Nervous System Diseases and Conditions.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2017, NewsRx LLC

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