Life Extension Update
|February 24, 2004|
|Life Extension Weekly Update Exclusive |
Fruit and grain fiber lower heart disease risk
The current study analyzed ten prospective studies that included 91,058 men and 245,186 women. Dietary intake of fiber was ascertained at the beginning of each study by the use of questionnaires completed by participants. Fiber intake from grains, fruits and vegetables was measured, as well as insoluble and soluble fiber. During six to ten years of follow-up, 5,249 cases or coronary heart disease were diagnosed and 2,011 deaths from the disease occurred.
Adjusted analysis found that each ten gram per day increment of fiber was related to a 14 percent decreased risk of coronary events and a 27 percent reduction in the risk of dying from heart disease. When analyzed separately, cereal fiber intake was associated with a 10 percent reduction in coronary events and a 25 percent reduction in coronary deaths, while fruit fiber intake was associated with an even lower risk of events and death, with a 16 percent and 30 percent reduction. Fiber from vegetables did not appear to be associated with either coronary events or deaths.
Mark Pereira, PhD, of the University of Minnesota, Minneapolis, and colleages conclude, "Our results suggest that dietary fiber intake during adulthood is inversely associated with CHD risk. Coronary risk was 10 percent to 30 percent lower for each 10 gram per day increment of total, cereal, or fruit fiber. Therefore, the recommendations to consume a diet that includes an abundance of fiber-rich foods to prevent CHD are based on a wealth of consistent scientific evidence. “
Illustrative of the value of fiber, researchers from the Veterans Affairs Medical Center, the University of Kentucky (Lexington), and the Procter & Gamble Company (Cincinnati, OH) evaluated the effectiveness of psyllium as a hypocholesterolemic and blood glucose modulator. Thirty-four men with Type II diabetes and mild-to-moderate hypercholesterolemia were randomly assigned to receive 5.1 grams of psyllium or a cellulose placebo twice daily for 8 weeks. The psyllium group showed significant improvements in glucose and lipid values compared with the placebo group. Serum total and LDL-cholesterol concentrations were 8.9% and 13.0% lower, respectively, in the psyllium group compared to the placebo group. All-day and postlunch postprandial glucose concentrations were 11.0% and 19.2% lower in the psyllium group (Anderson et al. 1999). These impressive results occur as fiber binds bile acids, cholesterol, and fats, preventing their absorption. Short-chain fatty acids, products of fiber fermentation in the colon, further inhibit cholesterol synthesis by the liver.
Studies in the New England Journal of Medicine confirmed the value of a high fiber diet in improving glycemic control and reducing hyperinsulinemia and plasma lipid levels in patients with Type II diabetes (Chandalia et al. 2000). In a randomized, 6-week crossover study, 13 patients with Type II diabetes were given diets containing either moderate or high amounts of fiber. The moderate fiber allowance was 24 grams (8 grams of soluble and 16 grams of insoluble), an amount compliant with guidelines established by the ADA. The high-fiber diet consisted of 50 grams of fiber (25 grams soluble and 25 grams insoluble).
During the sixth week of the high-fiber diet (as compared with the sixth week of the ADA diet) the diet supplying 50 grams a day of fiber lowered plasma glucose 10%, insulin concentrations 12%, total cholesterol 6.7%, triglyceride levels 10.2%, VLDL 12.5%, and LDL cholesterol 6.3%. It is speculated that the decrease in triglycerides and VLDL may be due more to improved glycemic control than to a direct relationship with the fiber. There was no significant difference between the two diets in terms of HDL cholesterol levels. Note: The fiber-rich foods included in the study were cantaloupe, grapefruit, raisins, oranges, papayas, lima beans, okra, sweet potatoes, winter squash, zucchini, oat bran, and oatmeal.
Fiber Food provides natural, bulk-producing soluble fiber. These fibers help maintain healthy bowel function and help to maintain cholesterol levels that are already within the normal range.* Fiber Food helps clean the walls of the intestines and enhances the elimination of fecal mutagens.
Herbal Cardiovascular Formula provides a variety of herbs, herbal extracts, and plant enzymes that may enhance cardiovascular health.
Bromelain is a mixture of sulfur-containing proteolytic enzymes obtained from the stem of the pineapple plant. Bromelain can help break down fibrous substances within the body so that they can be metabolized normally.
Curcumin can help maintain normal healthy platetlet function and the normal process of bile excretions.
Gugulipid can act as an antioxidant, while helping to maintain normal lipid levels and platelet function. Its primary action is in maintaining the liver’s metabolism of low-density lipoproteins.
Ginger, similar to curcumin, also maintains normal healthy platetlet function. Ginger also has the ability to optimize overall a healthy functioning heart.
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