Life Extension Update
Tuesday October 4, 2011. The August, 2011 issue of the Journal of Internal Medicine published the findings of American researchers of a reduction in the incidence of high blood pressure in men and women who consumed higher amounts of long-chain omega-3 polyunsaturated fatty acids from fish. While the cardiovascular benefits of long-chain omega-3 fatty acids (which include EPA and DHA) are well known, the current research sought to determine potential interactions with the body's levels of selenium and mercury, elements that also occur in fish.
The study involved 4,508 men and women enrolled in 1985 in the ongoing Coronary Artery Risk Development in Young Adults (CARDIA) Study. Dr Ka He of the University of North Carolina in Chapel Hill and colleagues utilized responses to dietary questionnaires conducted upon enrollment and at the seven and twenty year follow-up examinations to determine average omega-3 fatty acid intake. Blood pressure was measured at all six follow-up visits, and incidences of high blood pressure or initiation of antihypertensive medication were noted. Selenium and mercury levels were determined by measuring the amounts contained in toenail clippings collected in 1987.
Dr He's team found a 35 percent lower adjusted risk of developing hypertension among men and women whose EPA and DHA levels were among the top 25 percent in comparison with those whose intake was among the lowest fourth. When the fatty acids were separately evaluated, DHA was associated with the greatest protective effect. The benefit for omega-3 fatty acids appeared to be greater among those with higher selenium and lower mercury levels.
"To the best of our knowledge, no study has investigated three-way interactions of selenium, mercury and long-chain omega-3 polyunsaturated fatty acids in relation to incidence of hypertension," the authors write. "The possible mechanisms explaining the modification of selenium and mercury on the antihypertensive effect of long-chain omega-3 polyunsaturated fatty acids may lie in that both selenium and mercury are somehow involved in the process of oxidative stress and cardiac function through the same pathway by which long-chain omega-3 polyunsaturated fatty acids regulate blood pressure."
"Additional studies are warranted to elucidate the complex interactions amongst selenium, mercury and long-chain omega-3 polyunsaturated fatty acids, three important components in fish, in terms of hypertension prevention," they conclude.
This supplement should be taken in conjunction with a healthy diet and regular exercise program. Individual results are not guaranteed and results may vary.
**This offer good one time only. Shipping fees, Life Extension Magazine® subscriptions, CHOICE and Premier program fees, and purchases made with LE Dollars or gift cards do not count toward your order total. Your purchase must total $100 or more in a single order for the $10 discount to apply. Standard shipping and handling (regularly $5.50) in the U.S., includes Alaska and Hawaii.
The information provided on this site is for informational purposes only and is not intended as a substitute for advice from your physician or other health care professional or any information contained on or in any product label or packaging. You should not use the information on this site for diagnosis or treatment of any health problem or for prescription of any medication or other treatment. You should consult with a healthcare professional before starting any diet, exercise or supplementation program, before taking any medication, or if you have or suspect you might have a health problem. You should not stop taking any medication without first consulting your physician.
If you are not 100% satisfied with any purchase made directly from Life Extension®, just return your purchase within 12 months of original purchase date and we will either replace the product for you, credit your original payment method or credit your Life Extension account for the full amount of the original purchase price (less shipping and handling).
These statements have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure, or prevent any disease.