Life Extension Update
Wednesday, September 7, 2016
An article appearing in the American Journal of Clinical Nutrition on August 3, 2016, reveals an association between a higher intake of a type of flavonoid known as anthocyanins and a lower risk of fatal heart attack in men. An association was also found between increased consumption of another flavonoid compound known as flavanones and a lower risk of ischemic stroke.
Anthocyanins are found in red and blue fruits that include blueberries, blackberries, black plums, red grapes, raspberries, cherries, strawberries and red wine, while flavanones occur almost exclusively in citrus fruit. Both of these compounds are also available in nutritional supplements.
The study included 43,880 healthy men with no prior diagnosis of cardiovascular disease or cancer upon enrollment in the Health Professionals Follow-Up Study, which enrolled 51,529 men in 1986. Responses to dietary questionnaires completed every four years beginning in 1986 were analyzed for flavonoid intake, including anthocyanins and flavanones.
Over 24 years of follow-up, 1,824 fatal and 2,222 nonfatal heart attacks, and 901 ischemic and 671 nonischemic strokes occurred. Men whose anthocyanin intake was among the top 20% of subjects had a 13% lower adjusted risk of nonfatal heart attack in comparison with those whose intake was among the lowest 20%.
In men whose flavanone intake was among the top fifth, there was a 22% lower adjusted risk of ischemic stroke. This protective effect was most pronounced in men over the age of 65 years.
"Our findings suggest that bioactive compounds present in both citrus and red- or blue-colored fruits commonly consumed in the habitual diet may be associated with a lower risk of cardiovascular in men," conclude Aedín Cassidy of the University of East Anglia and colleagues. "Randomized trials focusing on commonly consumed anthocyanin- and flavanone-rich foods are also needed to examine dose-response effects, as are trials of longer duration to assess clinically relevant endpoints."
This supplement should be taken in conjunction with a healthy diet and regular exercise program. Individual results are not guaranteed and results may vary.
**This offer good one time only. Shipping fees, Life Extension Magazine® subscriptions, CHOICE and Premier program fees, and purchases made with LE Dollars or gift cards do not count toward your order total. Your purchase must total $100 or more in a single order for the $10 discount to apply. Standard shipping and handling (regularly $5.50) in the U.S., includes Alaska and Hawaii.
The information provided on this site is for informational purposes only and is not intended as a substitute for advice from your physician or other health care professional or any information contained on or in any product label or packaging. You should not use the information on this site for diagnosis or treatment of any health problem or for prescription of any medication or other treatment. You should consult with a healthcare professional before starting any diet, exercise or supplementation program, before taking any medication, or if you have or suspect you might have a health problem. You should not stop taking any medication without first consulting your physician.
If you are not 100% satisfied with any purchase made directly from Life Extension®, just return your purchase within 12 months of original purchase date and we will either replace the product for you, credit your original payment method or credit your Life Extension account for the full amount of the original purchase price (less shipping and handling).
These statements have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure, or prevent any disease.