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AAS. Amino Acid Studies. Benefits: Hair Loss and Preention with amino acids. Accessed 5/6/2016

Ahmed T, Das SK, Golden JK, Saltzman E, Roberts SB, Meydani SN. Calorie restriction enhances T-cell-mediated immune response in adult overweight men and women. The journals of gerontology. Series A, Biological sciences and medical sciences. Nov 2009;64(11):1107-1113.

Alkhawam L, Alam M. Dermabrasion and microdermabrasion. Facial plastic surgery : FPS. Dec 2009;25(5):301-310.

Amaro-Ortiz A, Yan B, D'Orazio JA. Ultraviolet radiation, aging and the skin: prevention of damage by topical cAMP manipulation. Molecules (Basel, Switzerland). 2014;19(5):6202-6219.

Angelo G. Oregon State University. Linus Pauling Institute. Micronutrient Center. Essential Fatty Acids and Skin Health February 2.

Angelo G.  Linus Pauling Institute. Micronutrient Information Center. Minerals and Skin Health. 1/2013. Accessed 5/9/2016.

Antoniou C, Kosmadaki MG, Stratigos AJ, Katsambas AD. Photoaging: prevention and topical treatments. Am J Clin Dermatol. 2010;11(2):95-102.

Araujo AR, Soares VP, Silva FS, Moreira Tda S. Radiofrequency for the treatment of skin laxity: mith or truth. Anais brasileiros de dermatologia. Sep-Oct 2015;90(5):707-721.

Arif T. Salicylic acid as a peeling agent: a comprehensive review. Clin Cosmet Investig Dermatol. 2015;8:455-461.

Ascenso A, Ribeiro H, Marques HC, Oliveira H, Santos C, Simoes S. Is tretinoin still a key agent for photoaging management? Mini reviews in medicinal chemistry. 2014;14(8):629-641.

ASDS. American Society for Dermatologic Surgery. Chemical Peels. Copyright 2016a. Accessed 9/13/2016.

ASDS. American Society for Dermatologic Surgery. Laser Resurfacing. Copyright 2016b. Accessed 3/7/2016

ASOPRS. American Society of Ophthalmic Plastic & Reconstructive Surgery. Restylane. Copyright 2015. Accessed 9/13/2016.

ASPS. American Society of Plastic Surgeons. Cosmetic page. Chemical Peel: Minimally Invasive Procedure. Copyright 2016a. Accessed 9/13/2016.

ASPS. American Society of Plastic Surgeons. Cosmetic page. Laser Skin Resurfacing. Copyright 2016b. Accessed 3/7/2016.

ASPS. American Society of Plastic Surgeons. Microdermabrasian Treatments: Microdermabrasion risks and safety. Copyright 2016c. Accessed 7/19/2016.

Bak H, Hong SP, Jeong SK, Choi EH, Lee SE, Lee SH, Ahn SK. Altered epidermal lipid layers induced by long-term exposure to suberythemal-dose ultraviolet. International journal of dermatology. Jul 2011;50(7):832-837.

Baldwin HE, Nighland M, Kendall C, Mays DA, Grossman R, Newburger J. 40 years of topical tretinoin use in review. Journal of drugs in dermatology: JDD. Jun 1 2013;12(6):638-642.

Bales CW, Kraus WE. Caloric restriction: implications for human cardiometabolic health. J Cardiopulm Rehabil Prev. Jul-Aug 2013;33(4):201-208.

BASF. Plant-based microspheres that fill in wrinkles and lines: Filling Spheres vegetal. Copyright 2014. Accessed 4/6/2016

Baspeyras M, Rouvrais C, Liegard L, et al. Clinical and biometrological efficacy of a hyaluronic acid-based mesotherapy product: a randomised controlled study. Archives for dermatological research. Archiv fur dermatologische Forschung. Oct 2013;305(8):673-682.

Baud S, Duca L, Bochicchio B, et al. Elastin peptides in aging and pathological conditions. Biomolecular concepts. Feb 2013;4(1):65-76.

Baumann L. Skin ageing and its treatment. The Journal of pathology. Jan 2007;211(2):241-251.

Beer C, Wood S, Veghte RH. A clinical trial to investigate the effect of Cynatine HNS on hair and nail parameters. TheScientificWorldJournal. 2014;2014:641723.

Beer C, Wood S, Veghte RH. A randomized, double-blind, placebo-controlled clinical trial to investigate the effect of Cynatine(®) HNS on skin characteristics. Int J Cosmet Sci. Dec 2013;35(6):608-612.

Besdine RW. Merck Manual. Consumer Version. Changes in the Body With Aging.’s-health-issues/the-aging-body/changes-in-the-body-with-agi. Copyright 2016. Accessed 9/13/2016.

Besedovsky L, Lange T, Born J. Sleep and immune function. Pflugers Arch. Jan 2012;463(1):121-137.

Bhattacharya S, Darjatmoko SR, Polans AS. Resveratrol modulates the malignant properties of cutaneous melanoma through changes in the activation and attenuation of the antiapoptotic protooncogenic protein Akt/PKB. Melanoma research. Jun 2011;21(3):180-187.

Bhattacharyya TK, Jackson P, Patel MK, Thomas JR. Epidermal cell proliferation in calorie-restricted aging rats. Current aging science. Jul 2012;5(2):96-104.

Bhattacharyya TK, Merz M, Thomas JR. Modulation of cutaneous aging with calorie restriction in Fischer 344 rats: a histological study. Archives of facial plastic surgery. Jan-Feb 2005;7(1):12-16.

Bickenbach JR, Stern MM, Grinnell KL, Manuel A, Chinnathambi S. Epidermal stem cells have the potential to assist in healing damaged tissues. The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research. Sep 2006;11(1):118-123.

Bonina F, Puglia C. Effect Of The Supplementation With Red Orange Complex On Ultraviolet-Induced Skin Damage In Human Volunteers. BIONAP: Bioactive Natural Products. Department of Pharmaceutical Sciences - University of Catania. Accessed 5/24/2016

Borg M, Brincat S, Camilleri G, Schembri-Wismayer P, Brincat M, Calleja-Agius J. The role of cytokines in skin aging. Climacteric : the journal of the International Menopause Society. Oct 2013;16(5):514-521.

Bosch R, Philips N, Suarez-Perez JA, Juarranz A, Devmurari A, Chalensouk-Khaosaat J, Gonzalez S. Mechanisms of Photoaging and Cutaneous Photocarcinogenesis, and Photoprotective Strategies with Phytochemicals. Antioxidants (Basel, Switzerland). 2015;4(2):248-268.

Botanigenics. Product monograph. Botanimoist AMS. Accessed 2/3/2016

Brandt FS, Cazzaniga A. Hyaluronic acid gel fillers in the management of facial aging. Clinical interventions in aging. 2008;3(1):153-159.

Burke KE. Photodamage of the skin: protection and reversal with topical antioxidants. Journal of cosmetic dermatology. Jul 2004;3(3):149-155.

Calleja-Agius J, Brincat M, Borg M. Skin connective tissue and ageing. Best practice & research. Clinical obstetrics & gynaecology. Oct 2013;27(5):727-740.

Calleja-Agius J, Muscat-Baron Y, Brincat MP. Skin ageing. Menopause international. Jun 2007;13(2):60-64.

Camacho FM, Garcia-Hernandez MJ. Zinc aspartate, biotin, and clobetasol propionate in the treatment of alopecia areata in childhood. Pediatric dermatology. Jul-Aug 1999;16(4):336-338.

Carlisle EM. Silicon as an essential trace element in animal nutrition. Ciba Foundation symposium. 1986;121:123-139.

Carniol PJ, Hamilton MM, Carniol ET. Current Status of Fractional Laser Resurfacing. JAMA facial plastic surgery. Sep-Oct 2015;17(5):360-366.

Centerchem. SYN®-TACKS. Copyright 2016. Accessed 9/13/2016.

Chamcheu JC, Siddiqui IA, Syed DN, Adhami VM, Liovic M, Mukhtar H. Keratin gene mutations in disorders of human skin and its appendages. Archives of biochemistry and biophysics. Apr 15 2011;508(2):123-137.

Charles-de-Sa L, Gontijo-de-Amorim NF, Maeda Takiya C, et al. Antiaging treatment of the facial skin by fat graft and adipose-derived stem cells. Plastic and reconstructive surgery. Apr 2015;135(4):999-1009.

Charruyer A, Ghadially R. What's new in dermatology: epidermal stem cells. G Ital Dermatol Venereol. Feb 2011;146(1):57-67.

Chen AC, Martin AJ, Choy B, et al. A Phase 3 Randomized Trial of Nicotinamide for Skin-Cancer Chemoprevention. The New England journal of medicine. Oct 22 2015;373(17):1618-1626.

Chen L, Qin F, Ge M, Shu Q, Xu J. Application of adipose-derived stem cells in heart disease. Journal of cardiovascular translational research. Oct 2014;7(7):651-663.

Chen Y, Lyga J. Brain-skin connection: stress, inflammation and skin aging. Inflammation & allergy drug targets. 2014;13(3):177-190.

Choi MJ, Maibach HI. Role of ceramides in barrier function of healthy and diseased skin. Am J Clin Dermatol. 2005;6(4):215-223.

Choudhry SZ, Bhatia N, Ceilley R, Hougeir F, Lieberman R, Hamzavi I, Lim HW. Role of oral Polypodium leucotomos extract in dermatologic diseases: a review of the literature. Journal of drugs in dermatology: JDD. Feb 2014;13(2):148-153.

CIHR. Canadian Institute of Health Research. DrugBank. Tretinoin. Last updated 9/13/2016. Accessed 9/13/2016.

Clemente-Postigo M, Munoz-Garach A, Serrano M, et al. Serum 25-hydroxyvitamin D and adipose tissue vitamin D receptor gene expression: relationship with obesity and type 2 diabetes. The Journal of clinical endocrinology and metabolism. Apr 2015;100(4):E591-595.

Colombo VE, Gerber F, Bronhofer M, Floersheim GL. Treatment of brittle fingernails and onychoschizia with biotin: scanning electron microscopy. J Am Acad Dermatol. Dec 1990;23(6 Pt 1):1127-1132.

CPCE. Collagen Peptide Clinical Evidence. Accessed 5/9/2016

Culp L, Moradi Tuchayi S, Alinia H, Feldman SR. Tolerability of Topical Retinoids: Are There Clinically Meaningful Differences Among Topical Retinoids? Journal of cutaneous medicine and surgery. Nov-Dec 2015;19(6):530-538.

Dahl MV. NEJM Journal Watch [online]. Fragility in Aged Skin - It's Not the Fibroblasts 5/5/2010. Accessed 9/13/2016.

Delazar A, Khodaie L, Afshar J, Nahar L, Sarker SD. Isolation and free-radical-scavenging properties of cyanidin 3-O-glycosides from the fruits of Ribes biebersteinii Berl. Acta pharmaceutica (Zagreb, Croatia). Mar 2010;60(1):1-11.

Di Marzio L, Cinque B, Cupelli F, De Simone C, Cifone MG, Giuliani M. Increase of skin-ceramide levels in aged subjects following a short-term topical application of bacterial sphingomyelinase from Streptococcus thermophilus. International journal of immunopathology and pharmacology. Jan-Mar 2008;21(1):137-143.

Dover JS, Zelickson B. Results of a survey of 5,700 patient monopolar radiofrequency facial skin tightening treatments: assessment of a low-energy multiple-pass technique leading to a clinical end point algorithm. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]. Aug 2007;33(8):900-907.

Drake VJ. Oregon State University. Linus Pauling Institute. Micronutreint Center. Vitamin D and Skin Health. 11/2011. Accessed 9/13/2016.

Dreher F, Gabard B, Schwindt DA, Maibach HI. Topical melatonin in combination with vitamins E and C protects skin from ultraviolet-induced erythema: a human study in vivo. Br J Dermatol. Aug 1998;139(2):332-339.

Dunbar SW, Goldberg DJ. Radiofrequency in Cosmetic Dermatology: An Update. Journal of drugs in dermatology: JDD. Nov 1 2015;14(11):1229-1238.

Dunn JH, Koo J. Psychological Stress and skin aging: a review of possible mechanisms and potential therapies. Dermatology online journal. Jun 2013;19(6):18561.

Ead RD. Oral zinc sulphate in alopacia areata-a double blind trial. Br J Dermatol. Apr 1981;104(4):483-484.

Edwards PC, Fantasia JE. Review of long-term adverse effects associated with the use of chemically-modified animal and nonanimal source hyaluronic acid dermal fillers. Clinical interventions in aging. 2007;2(4):509-519.

El-Alfy M, Deloche C, Azzi L, et al. Skin responses to topical dehydroepiandrosterone: implications in antiageing treatment? Br J Dermatol. Nov 2010;163(5):968-976.

El-Domyati M, Hosam W, Abdel-Azim E, Abdel-Wahab H, Mohamed E. Microdermabrasion: a clinical, histometric, and histopathologic study. Journal of cosmetic dermatology. Jun 29 2016.

El-Haj N, Goldstein N. Sun protection in a pill: the photoprotective properties of Polypodium leucotomos extract. International journal of dermatology. Mar 2015;54(3):362-366.

Evans JA, Johnson EJ. The role of phytonutrients in skin health. Nutrients. Aug 2010;2(8):903-928.

Farage MA, Miller KW, Elsner P, Maibach HI. Characteristics of the Aging Skin. Advances in wound care. Feb 2013;2(1):5-10.

Farris P, Krutmann J, Li YH, McDaniel D, Krol Y. Resveratrol: a unique antioxidant offering a multi-mechanistic approach for treating aging skin. Journal of drugs in dermatology : JDD. Dec 2013;12(12):1389-1394.

FDA. U.S. Food and Drug Administration. Medical Devices page. Restylane Silk Injectable Gel - P040024/S072. Last updated 1/11/2016. Accessed 4/26/2016.

Felipe DL, Hempe JM, Liu S, Matter N, Maynard J, Linares C, Chalew SA. Skin intrinsic fluorescence is associated with hemoglobin A(1c )and hemoglobin glycation index but not mean blood glucose in children with type 1 diabetes. Diabetes care. Aug 2011;34(8):1816-1820.

Fernandes G, Venkatraman JT, Turturro A, Attwood VG, Hart RW. Effect of food restriction on life span and immune functions in long-lived Fischer-344 x Brown Norway F1 rats. Journal of clinical immunology. Jan 1997;17(1):85-95.

Fischer TW, Slominski A, Zmijewski MA, Reiter RJ, Paus R. Melatonin as a major skin protectant: from free radical scavenging to DNA damage repair. Experimental dermatology. Sep 2008;17(9):713-730.

Fitzpatrick RE, Rostan EF. Double-blind, half-face study comparing topical vitamin C and vehicle for rejuvenation of photodamage. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]. Mar 2002;28(3):231-236.

Floersheim GL. [Treatment of brittle fingernails with biotin]. Zeitschrift fur Hautkrankheiten. Jan 15 1989;64(1):41-48.

Fontana L, Meyer TE, Klein S, Holloszy JO. Long-term calorie restriction is highly effective in reducing the risk for atherosclerosis in humans. Proceedings of the National Academy of Sciences of the United States of America. Apr 27 2004;101(17):6659-6663.

Franca Wanick FB, Almeida Issa MC, Luiz RR, Soares Filho PJ, Olej B. Skin Remodeling Using Hyaluronic Acid Filler Injections in Photo-Aged Faces. Dermatologic surgery: official publication for American Society for Dermatologic Surgery [et al.]. Mar 2016;42(3):352-359.

Fujikawa H, Fujimoto A, Farooq M, Ito M, Shimomura Y. Characterization of the human hair keratin-associated protein 2 (KRTAP2) gene family. The Journal of investigative dermatology. Jul 2012;132(7):1806-1813.

Geng A, Weinstock MA, Hall R, et al. Tolerability of high-dose topical tretinoin: the Veterans Affairs Topical Tretinoin Chemoprevention Trial. British Journal of Dermatology. 2009;161(4):918-924.

Giesen M, Gruedl S, Holtkoetter O, Fuhrmann G, Koerner A, Petersohn D. Ageing processes influence keratin and KAP expression in human hair follicles. Experimental dermatology. Sep 2011;20(9):759-761.

Gkogkolou P, Bohm M. Advanced glycation end products: Key players in skin aging? Dermato-endocrinology. Jul 1 2012;4(3):259-270.

Gold MH. Medscape Multispecialty. The Increasing Use of Nonablative Radiofredquency in the Rejuvenation of the Skin. Vol. 2016. 2011.

Gold MH. Use of hyaluronic acid fillers for the treatment of the aging face. Clinical interventions in aging. 2007;2(3):369-376.

Grossman R. The role of dimethylaminoethanol in cosmetic dermatology. Am J Clin Dermatol. 2005;6(1):39-47.

Guillou S, Ghabri S, Jannot C, Gaillard E, Lamour I, Boisnic S. The moisturizing effect of a wheat extract food supplement on women's skin: a randomized, double-blind placebo-controlled trial. Int J Cosmet Sci. Apr 2011;33(2):138-143.

Gupta MA, Gilchrest BA. Psychosocial aspects of aging skin. Dermatologic clinics. Oct 2005;23(4):643-648.

Hagenau T, Vest R, Gissel TN, Poulsen CS, Erlandsen M, Mosekilde L, Vestergaard P. Global vitamin D levels in relation to age, gender, skin pigmentation and latitude: an ecologic meta-regression analysis. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. Jan 2009;20(1):133-140.

Halbina A, Trznadel-Grodzka E, Rotsztejn H. Fractional laser therapy - the next step in alleviating the symptoms of skin aging (own observations). Przeglad menopauzalny = Menopause review. May 2014;13(2):132-135.

Hamers L. One reason your hair is thinning? Some of it turns into skin. Science: American Academy for the Advancement of Science. 2/4/2016. Accessed 5/6/2016

Hassan KM, Benedetto AV. Facial skin rejuvenation: ablative laser resurfacing, chemical peels, or photodynamic therapy? Facts and controversies. Clinics in dermatology. Nov-Dec 2013;31(6):737-740.

Heinrich U, Moore CE, De Spirt S, Tronnier H, Stahl W. Green tea polyphenols provide photoprotection, increase microcirculation, and modulate skin properties of women. The Journal of nutrition. Jun 2011;141(6):1202-1208.

Hexsel C, Hexsel D, Porto MD, Schilling J, Siega C. Botulinum toxin type A for aging face and aesthetic uses. Dermatologic therapy. Jan-Feb 2011;24(1):54-61.

HHP. Harvard Health Publications. Harvard Medical School. What are bioidentical hormones? Copyright 2016. Accessed 9/13/2016.

Higdon J. Linus Pauling Institute. Micronutrient Information Center. Biotin. Last updated 10/21/2015a. Accessed 5/9/2016

Higdon J. Linus Pauling Institute. Micronutrient Information Center. Pantothenic Acid: Wound Healing. Last updated 7/2015b. Accessed 5/9/2016

Higdon J. Linus Pauling Institute. Micronutrient Center. Resveratrol. Last updated 6/11/2015c. Accessed 9/13/2016.

Holick MF, Chen TC. Vitamin D deficiency: a worldwide problem with health consequences. The American journal of clinical nutrition. Apr 2008;87(4):1080s-1086s.

Holtorf K. The bioidentical hormone debate: are bioidentical hormones (estradiol, estriol, and progesterone) safer or more efficacious than commonly used synthetic versions in hormone replacement therapy? Postgraduate medicine. Jan 2009;121(1):73-85.

Hughes MC, Williams GM, Baker P, Green AC. Sunscreen and prevention of skin aging: a randomized trial. Ann Intern Med. Jun 4 2013;158(11):781-790.

Humbert PG, Haftek M, Creidi P, et al. Topical ascorbic acid on photoaged skin. Clinical, topographical and ultrastructural evaluation: double-blind study vs. placebo. Experimental dermatology. Jun 2003;12(3):237-244.

Iannacone MR, Hughes MC, Green AC. Effects of sunscreen on skin cancer and photoaging. Photodermatology, photoimmunology & photomedicine. Apr-Jun 2014;30(2-3):55-61.

Iannitti T, Morales-Medina JC, Coacci A, Palmieri B. Experimental and Clinical Efficacy of Two Hyaluronic Acid-based Compounds of Different Cross-Linkage and Composition in the Rejuvenation of the Skin. Pharmaceutical research. Jun 25 2014.

James MJ, Gibson RA, Cleland LG. Dietary polyunsaturated fatty acids and inflammatory mediator production. The American journal of clinical nutrition. Jan 2000;71(1 Suppl):343s-348s.

Jang M, Cai L, Udeani GO, et al. Cancer chemopreventive activity of resveratrol, a natural product derived from grapes. Science (New York, N.Y.). Jan 10 1997;275(5297):218-220.

Jensen JM, Forl M, Winoto-Morbach S, Seite S, Schunck M, Proksch E, Schutze S. Acid and neutral sphingomyelinase, ceramide synthase, and acid ceramidase activities in cutaneous aging. Experimental dermatology. Aug 2005;14(8):609-618.

Jugdaohsingh R. Silicon and bone health. The journal of nutrition, health & aging. Mar-Apr 2007;11(2):99-110.

Kadler KE, Baldock C, Bella J, Boot-Handford RP. Collagens at a glance. Journal of cell science. Jun 15 2007;120(Pt 12):1955-1958.

Kahan V, Andersen ML, Tomimori J, Tufik S. Can poor sleep affect skin integrity? Medical hypotheses. Dec 2010;75(6):535-537.

Kambayashi H, Yamashita M, Odake Y, Takada K, Funasaka Y, Ichihashi M. Epidermal changes caused by chronic low-dose UV irradiation induce wrinkle formation in hairless mouse. Journal of dermatological science. Aug 2001;27 Suppl 1:S19-25.

Katsuoka K, Mauch C, Schell H, Hornstein OP, Krieg T. Collagen-type synthesis in human-hair papilla cells in culture. Archives of Dermatological Research. 1988;280(3):140-144.

Katta R, Desai SP. Diet and dermatology: the role of dietary intervention in skin disease. The Journal of clinical and aesthetic dermatology. Jul 2014;7(7):46-51.

Kim DH, Je YJ, Kim CD, Lee YH, Seo YJ, Lee JH, Lee Y. Can Platelet-rich Plasma Be Used for Skin Rejuvenation? Evaluation of Effects of Platelet-rich Plasma on Human Dermal Fibroblast. Annals of dermatology. 2011;23(4):424-431.

Kim HH, Cho S, Lee S, Kim KH, Cho KH, Eun HC, Chung JH. Photoprotective and anti-skin-aging effects of eicosapentaenoic acid in human skin in vivo. Journal of lipid research. May 2006;47(5):921-930.

Kim HH, Shin CM, Park CH, Kim KH, Cho KH, Eun HC, Chung JH. Eicosapentaenoic acid inhibits UV-induced MMP-1 expression in human dermal fibroblasts. Journal of lipid research. Aug 2005;46(8):1712-1720.

Kim JE, Shin MH, Chung JH. Epigallocatechin-3-gallate prevents heat shock-induced MMP-1 expression by inhibiting AP-1 activity in human dermal fibroblasts. Archives for dermatological research. Archiv fur dermatologische Forschung. Sep 2013;305(7):595-602.

Kim KH, Back JH, Zhu Y, et al. Resveratrol targets transforming growth factor-beta2 signaling to block UV-induced tumor progression. The Journal of investigative dermatology. Jan 2011;131(1):195-202.

Kim WS, Park BS, Park SH, Kim HK, Sung JH. Antiwrinkle effect of adipose-derived stem cell: activation of dermal fibroblast by secretory factors. J Dermatol Sci. Feb 2009;53(2):96-102.

Kligman AM. Guidelines for the use of topical tretinoin (Retin-A) for photoaged skin. Journal of the American Academy of Dermatology. Sep 1989;21(3 Pt 2):650-654.

Konda D, Thappa DM. Mesotherapy: What is new? Indian journal of dermatology, venereology and leprology. Jan-Feb 2013;79(1):127-134.

Koster MI. Making an epidermis. Annals of the New York Academy of Sciences. Jul 2009;1170:7-10.

Krueger N, Sadick NS. New-generation radiofrequency technology. Cutis. Jan 2013;91(1):39-46.

Lefevre M, Redman LM, Heilbronn LK, et al. Caloric restriction alone and with exercise improves CVD risk in healthy non-obese individuals. Atherosclerosis. Mar 2009;203(1):206-213.

Levinbook WS. Merck Manual. Consumer Version. Overview of Hair Growth. Copyright 2016. Accessed 9/13/2016.

Lijnen P, Petrov V. Transforming growth factor-beta 1-induced collagen production in cultures of cardiac fibroblasts is the result of the appearance of myofibroblasts. Methods and findings in experimental and clinical pharmacology. Jul-Aug 2002;24(6):333-344.

Lim HW, Wang SQ. The Skin Cancer Foundation's Guide to Suncreens. 7/3/2012. Accessed 5/2/2016.

Lipotec. Uplevity. 6/2013. Accessed 9/13/2016.

Lipozencic J, Bukvic-Mokos Z. Corrective dermatology today. Acta clinica Croatica. Dec 2010a;49(4):519-523.

Lipozencic J, Bukvic Mokos Z. Dermatologic lasers in the treatment of aging skin. Acta dermatovenerologica Croatica : ADC. 2010b;18(3):176-180.

Loesch MM, Somani AK, Kingsley MM, Travers JB, Spandau DF. Skin resurfacing procedures: new and emerging options. Clin Cosmet Investig Dermatol. 2014;7:231-241.

Louis A, Petereit F, Lechtenberg M, Deters A, Hensel A. Phytochemical characterization of Rhododendron ferrugineum and in vitro assessment of an aqueous extract on cell toxicity. Planta medica. Oct 2010;76(14):1550-1557.

Lu'o'ng KV, Nguyen LT. The role of vitamin D in Alzheimer's disease: possible genetic and cell signaling mechanisms. Am J Alzheimers Dis Other Demen. Mar 2013;28(2):126-136.

Lukes M, Prochazkova L, Shmidt V, Nedbalova L, Kaftan D. Temperature dependence of photosynthesis and thylakoid lipid composition in the red snow alga Chlamydomonas cf. nivalis (Chlorophyceae). FEMS microbiology ecology. Aug 2014;89(2):303-315.

Makrantonaki E, Schonknecht P, Hossini AM, et al. Skin and brain age together: The role of hormones in the ageing process. Experimental gerontology. Oct 2010;45(10):801-813.

Mammone T, Gan D, Goyarts E, Maes D. Salicylic acid protects the skin from UV damage. Journal of cosmetic science. Mar-Apr 2006;57(2):203-204.

Mandy SH. Tretinoin in the preoperative and postoperative management of dermabrasion. Journal of the American Academy of Dermatology. Oct 1986;15(4 Pt 2):878-879, 888-879.

Manna F, Dentini M, Desideri P, De Pita O, Mortilla E, Maras B. Comparative chemical evaluation of two commercially available derivatives of hyaluronic acid (hylaform from rooster combs and restylane from streptococcus) used for soft tissue augmentation. Journal of the European Academy of Dermatology and Venereology : JEADV. Nov 1999;13(3):183-192.

Manson JE, Chlebowski RT, Stefanick ML, et al. Menopausal hormone therapy and health outcomes during the intervention and extended poststopping phases of the Women's Health Initiative randomized trials. JAMA : the journal of the American Medical Association. Oct 2013;310(13):1353-1368.

Margadant C, Charafeddine RA, Sonnenberg A. Unique and redundant functions of integrins in the epidermis. FASEB journal: official publication of the Federation of American Societies for Experimental Biology. Nov 2010;24(11):4133-4152.

Martin KR. Silicon: the health benefits of a metalloid. Metal ions in life sciences. 2013;13:451-473.

Mayo Clinic. Diseases and Conditions: Wrinkles. Available at Last updated 10/21/2014. Accessed 07/27/2016.

McLafferty E, Hendry C, Alistair F. The integumentary system: anatomy, physiology and function of skin. Nursing standard (Royal College of Nursing (Great Britain): 1987). Sep 19-25 2012;27(3):35-42.

Metabiotics. Product monograph. Resveratrol. January 29, 2009.

Meyer TE, Kovacs SJ, Ehsani AA, Klein S, Holloszy JO, Fontana L. Long-term caloric restriction ameliorates the decline in diastolic function in humans. Journal of the American College of Cardiology. Jan 17 2006;47(2):398-402.

Michan S. Calorie restriction and NAD(+)/sirtuin counteract the hallmarks of aging. Frontiers in bioscience (Landmark edition). 2014;19:1300-1319.

Michels AJ. Linus Pauling Institute. Micronutrient Information Center. Micronutrients and Skin Health. 9/2011. Accessed 9/13/2016.

Miller AB, Breen M, Murphy KE. Chromosomal localization of acidic and basic keratin genes of the domestic dog. Mammalian genome: official journal of the International Mammalian Genome Society. Apr 1999;10(4):371-375.

Mizuno H, Tobita M, Uysal AC. Concise review: Adipose-derived stem cells as a novel tool for future regenerative medicine. Stem cells (Dayton, Ohio). May 2012;30(5):804-810.

Montemurro B, Gillen MM. Wrinkles and sagging flesh: exploring transformations in women's sexual body image. Journal of women & aging. 2013;25(1):3-23.

Morasso MI, Tomic-Canic M. Epidermal stem cells: the cradle of epidermal determination, differentiation and wound healing. Biology of the cell / under the auspices of the European Cell Biology Organization. Mar 2005;97(3):173-183.

Morini F, Dusatti F, Bonina FP, Saija A, Ferro M. Iron-induced Lipid Peroxidation in Human Skin-derived Cell Lines: Protection by a Red Orange Extract. Alternatives to laboratory animals: ATLA. May-Jun 2000;28(3):427-433.

Morita A. Tobacco smoke causes premature skin aging. J Dermatol Sci. Dec 2007;48(3):169-175.

Mostafa WZ, Hegazy RA. Vitamin D and the skin: Focus on a complex relationship: A review. Journal of advanced research. Nov 2015;6(6):793-804.

Mukherjee S, Date A, Patravale V, Korting HC, Roeder A, Weindl G. Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clinical interventions in aging. 2006;1(4):327-348.

Ndiaye M, Philippe C, Mukhtar H, Ahmad N. The grape antioxidant resveratrol for skin disorders: promise, prospects, and challenges. Archives of biochemistry and biophysics. Apr 15 2011;508(2):164-170.

Nestor MS, Berman B, Swenson N. Safety and Efficacy of Oral Polypodium leucotomos Extract in Healthy Adult Subjects. The Journal of clinical and aesthetic dermatology. Feb 2015;8(2):19-23.

NIH. National Cancer Institute. NCI Dictionary of Cancer Terms. Keratin Accessed 9/13/2016.

Niren NM. Pharmacologic doses of nicotinamide in the treatment of inflammatory skin conditions: a review. Cutis. Jan 2006;77(1 Suppl):11-16.

NLM. U.S. National Library of Medicine. Aging changes in hair and nails. Last updated 8/23/2016a. Accessed 9/13/2016.

NLM. U.S. National Library of Medicine. Skin Aging. Last updated 8/23/2016. Last updated 8/23/2016b. Accessed 9/13/2016.

Nouveau S, Bastien P, Baldo F, de Lacharriere O. Effects of topical DHEA on aging skin: a pilot study. Maturitas. Feb 20 2008;59(2):174-181.

Okawa T, Yamaguchi Y, Takada S, et al. Oral administration of collagen tripeptide improves dryness and pruritus in the acetone-induced dry skin model. J Dermatol Sci. May 2012;66(2):136-143.

OPT. Oldways Preservation Trust. Traditional Med Diet. Accessed 4/26/2016

Ortonne JP. Pigmentary changes of the ageing skin. Br J Dermatol. Apr 1990;122 Suppl 35:21-28.

Oyetakin-White P, Suggs A, Koo B, Matsui MS, Yarosh D, Cooper KD, Baron ED. Does poor sleep quality affect skin ageing? Clinical and experimental dermatology. Jan 2015;40(1):17-22.

Pageon H. Reaction of glycation and human skin: the effects on the skin and its components, reconstructed skin as a model. Pathologie-biologie. Jun 2010;58(3):226-231.

Pageon H, Zucchi H, Rousset F, Monnier VM, Asselineau D. Skin aging by glycation: lessons from the reconstructed skin model. Clinical chemistry and laboratory medicine : CCLM / FESCC. Jan 1 2014;52(1):169-174.

Pak C, Park J, Hong J, Jeong J, Bang S, Heo CY. A Phase III, Randomized, Multi-Center, Double-Masked, Matched-Pairs, Active-Controlled Trial to Compare the Efficacy and Safety between Neuramis Deep and Restylane in the Correction of Nasolabial Folds. Archives of plastic surgery. Nov 2015;42(6):721-728.

Palacios C, Gonzalez L. Is vitamin D deficiency a major global public health problem? The Journal of steroid biochemistry and molecular biology. Oct 2014;144 Pt A:138-145.

Pandel R, Poljšak B, Godic A, Dahmane R. Skin Photoaging and the Role of Antioxidants in Its Prevention. ISRN Dermatology. 2013;2013:930164.

Park BS, Jang KA, Sung JH, Park JS, Kwon YH, Kim KJ, Kim WS. Adipose-derived stem cells and their secretory factors as a promising therapy for skin aging. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]. Oct 2008;34(10):1323-1326.

Pavicic T, Gauglitz GG, Lersch P, Schwach-Abdellaoui K, Malle B, Korting HC, Farwick M. Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of drugs in dermatology: JDD. Sep 2011;10(9):990-1000.

Pei XR, Yang RY, Zhang ZF, Xu YJ, Han XL, Wang JB, Li Y. [Effects of marine collagen peptide on delaying the skin aging]. Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]. Apr 2008;42(4):235-238.

Peng Y, Reyes JL, Wei H, et al. RcDhn5, a cold acclimation-responsive dehydrin from Rhododendron catawbiense rescues enzyme activity from dehydration effects in vitro and enhances freezing tolerance in RcDhn5-overexpressing Arabidopsis plants. Physiologia plantarum. Dec 2008;134(4):583-597.

Philips N, Conte J, Chen YJ, et al. Beneficial regulation of matrixmetalloproteinases and their inhibitors, fibrillar collagens and transforming growth factor-beta by Polypodium leucotomos, directly or in dermal fibroblasts, ultraviolet radiated fibroblasts, and melanoma cells. Archives for dermatological research. Archiv fur dermatologische Forschung. Aug 2009;301(7):487-495.

Phillips TJ, Demircay Z, Sahu M. Hormonal effects on skin aging. Clin Geriatr Med. Nov 2001;17(4):661-672, vi.

PhytoCellTec. PhytoCellTec Alp Rose. Copyright 2010. Accessed 9/13/2016.

Piccardi N, Manissier P. Nutrition and nutritional supplementation: Impact on skin health and beauty. Dermato-endocrinology. Sep 2009;1(5):271-274.

Pilkington SM, Massey KA, Bennett SP, et al. Randomized controlled trial of oral omega-3 PUFA in solar-simulated radiation-induced suppression of human cutaneous immune responses. The American journal of clinical nutrition. Mar 2013;97(3):646-652.

Prentice RL. Postmenopausal Hormone Therapy and the Risks of Coronary Heart Disease, Breast Cancer, and Stroke. Seminars in reproductive medicine. 2014;32(6):419-425.

Prikhnenko S. Polycomponent mesotherapy formulations for the treatment of skin aging and improvement of skin quality. Clin Cosmet Investig Dermatol. 2015;8:151-157.

Proksch E, Schunck M, Zague V, Segger D, Degwert J, Oesser S. Oral intake of specific bioactive collagen peptides reduces skin wrinkles and increases dermal matrix synthesis. Skin Pharmacol Physiol. 2014;27(3):113-119.

Proksch E, Segger D, Degwert J, Schunck M, Zague V, Oesser S. Oral supplementation of specific collagen peptides has beneficial effects on human skin physiology: a double-blind, placebo-controlled study. Skin Pharmacol Physiol. 2014;27(1):47-55.

Puglia C, Offerta A, Saija A, Trombetta D, Venera C. Protective effect of red orange extract supplementation against UV-induced skin damages: photoaging and solar lentigines. Journal of cosmetic dermatology. Jun 2014;13(2):151-157.

Puizina-Ivic N, Miric L, Carija A, Karlica D, Marasovic D. Modern approach to topical treatment of aging skin. Collegium antropologicum. Sep 2010;34(3):1145-1153.

Purdue University. Food Chemistry 45300. Gelatin. [Powerpoint Presentation]. Accessed 5/9/2016

Pyun HB, Kim M, Park J, et al. Effects of Collagen Tripeptide Supplement on Photoaging and Epidermal Skin Barrier in UVB-exposed Hairless Mice. Preventive nutrition and food science. Dec 2012;17(4):245-253.

Quan T, Qin Z, Xia W, Shao Y, Voorhees JJ, Fisher GJ. Matrix-degrading metalloproteinases in photoaging. The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research. Aug 2009;14(1):20-24.

Quan T, Shao Y, He T, Voorhees JJ, Fisher GJ. Reduced expression of connective tissue growth factor (CTGF/CCN2) mediates collagen loss in chronologically aged human skin. The Journal of investigative dermatology. Feb 2010;130(2):415-424.

Rabionet M, Gorgas K, Sandhoff R. Ceramide synthesis in the epidermis. Biochimica et biophysica acta. Mar 2014;1841(3):422-434.

Raschke T, Koop U, Dusing HJ, et al. Topical activity of ascorbic acid: from in vitro optimization to in vivo efficacy. Skin Pharmacol Physiol. Jul-Aug 2004;17(4):200-206.

Ravussin E, Redman LM, Rochon J, et al. A 2-Year Randomized Controlled Trial of Human Caloric Restriction: Feasibility and Effects on Predictors of Health Span and Longevity. The journals of gerontology. Series A, Biological sciences and medical sciences. Sep 2015;70(9):1097-1104.

Reichrath J. Unravelling of hidden secrets: The role of vitamin D in skin aging. Dermato-endocrinology. Jul 1 2012;4(3):241-244.

Rhie G, Shin MH, Seo JY, et al. Aging- and photoaging-dependent changes of enzymic and nonenzymic antioxidants in the epidermis and dermis of human skin in vivo. The Journal of investigative dermatology. Nov 2001;117(5):1212-1217.

Riso P, Visioli F, Grande S, et al. Effect of a tomato-based drink on markers of inflammation, immunomodulation, and oxidative stress. J Agric Food Chem. 2006;54(7):2563-2566.

Rizwan M, Rodriguez-Blanco I, Harbottle A, et al. Tomato paste rich in lycopene protects against cutaneous photodamage in humans in vivo: a randomized controlled trial. Br J Dermatol.


Rizza W, Veronese N, Fontana L. What are the roles of calorie restriction and diet quality in promoting healthy longevity? Ageing Res Rev. Jan 2014;13:38-45.

Rosenberg S, OSTER KA, KALLOS A, BURROUGHS W. Further studies in the use of gelatin in the treatment of brittle nails. AMA archives of dermatology. 1957;76(3):330-335.

Rossouw JE, Anderson GL, Prentice RL, et al. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women's Health Initiative randomized controlled trial. JAMA: the journal of the American Medical Association. Jul 2002;288(3):321-333.

Saewan N, Jimtaisong A. Natural products as photoprotection. Journal of cosmetic dermatology. Mar 2015;14(1):47-63.

Sage RJ, Lim HW. Therapeutic Hotline: Recommendations on photoprotection and vitamin D. Dermatologic therapy. Jan-Feb 2010;23(1):82-85.

Saito S, Katoh M, Masumoto M, Matsumoto S, Masuho Y. Involvement of MMP-1 and MMP-3 in collagen degradation induced by IL-1 in rabbit cartilage explant culture. Life sciences. 1998;62(22):Pl 359-365.

Samaras N, Samaras D, Forster A, Frangos E, Philippe J. [Age related dehydroepiandrosterone decrease: clinical significance and therapeutic interest]. Revue medicale suisse. Jan 28


Sanguineti R, Puddu A, Mach F, Montecucco F, Viviani GL. Advanced glycation end products play adverse proinflammatory activities in osteoporosis. Mediators of inflammation. 2014;2014:975872.

Sator PG, Schmidt JB, Rabe T, Zouboulis CC. Skin aging and sex hormones in women -- clinical perspectives for intervention by hormone replacement therapy. Experimental dermatology. 2004;13 Suppl 4:36-40.

Sauermann K, Jaspers S, Koop U, Wenck H. Topically applied vitamin C increases the density of dermal papillae in aged human skin. BMC dermatology. Sep 29 2004;4(1):13.

Savoia A, Landi S, Baldi A. A new minimally invasive mesotherapy technique for facial rejuvenation. Dermatology and therapy. Jun 2013;3(1):83-93.

Saxon SV, Etten MJ, Perkins EA, Ebooks C. Physical change & aging: a guide for the helping professions. Vol 5th. New York: Springer Publishing Company; 2010.

Schagen SK, Zampeli VA, Makrantonaki E, Zouboulis CC. Discovering the link between nutrition and skin aging. Dermatoendocrinol. Jul 1 2012;4(3):298-307.

Scheinfeld N, Dahdah MJ, Scher R. Vitamins and minerals: their role in nail health and disease. Journal of drugs in dermatology : JDD. Aug 2007;6(8):782-787.

Schmidt JB, Binder M, Demschik G, Bieglmayer C, Reiner A. TREATMENT OF SKIN AGING WITH TOPICAL ESTROGENS. International journal of dermatology. 1996;35(9):669-674.

Schwimmer M, Mulinos M. Salutary effects of gelatin on nail defects in normal subjects. Plastic and reconstructive surgery. 1957;20(5):415-416.

Seaborn CD NF. Silicon: a nutritional beneficence fro bones, brains, and blood vessels? Nutrition Today. July/August1993.

Seaborn CD, Nielsen FH. Silicon deprivation decreases collagen formation in wounds and bone, and ornithine transaminase enzyme activity in liver. Biological trace element research. Dec 2002;89(3):251-261.

Sederma. New Products. Matrixyl synthe' 6. Copyright 2016. Accessed 9/13/2016.

Sheth H, Sheth J, Sheth F, Burn J. The poor patient with diabetes 'should live like a saint'. Diabetic medicine : a journal of the British Diabetic Association. Jun 4 2015.

Shin MH, Rhie GE, Park CH, Kim KH, Cho KH, Eun HC, Chung JH. Modulation of collagen metabolism by the topical application of dehydroepiandrosterone to human skin. The Journal of investigative dermatology. Feb 2005;124(2):315-323.

Simmons BJ, Griffith RD, Falto-Aizpurua LA, Nouri K. Use of radiofrequency in cosmetic dermatology: focus on nonablative treatment of acne scars. Clin Cosmet Investig Dermatol. 2014;7:335-339.

Singh VP, Bali A, Singh N, Jaggi AS. Advanced glycation end products and diabetic complications. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology. Feb 2014;18(1):1-14.

Skjot-Arkil H, Clausen RE, Nguyen QH, et al. Measurement of MMP-9 and -12 degraded elastin (ELM) provides unique information on lung tissue degradation. BMC pulmonary medicine. 2012;12:34.

Slonim AE, Sadick N, Pugliese M, Meyers-Seifer CH. Clinical response of alopecia, trichorrhexis nodosa, and dry, scaly skin to zinc supplementation. J Pediatr. Dec 1992;121(6):890-895.

Small R. Botulinum toxin injection for facial wrinkles. American family physician. Aug 1 2014;90(3):168-175.

Snow-Algae. Proven Efficacy. AMPK Activation. Copyright 2014a. Accessed 9/13/2016..

Snow-Algae. Proven Efficacy. Klotho, a Gene for Longevity. Copyright 2014b. Accessed 9/13/2016.

Snow-Algae. Proven Efficacy. Strong Skin Barrier. Copyright 2014c. Accessed 9/13/2016.

Sonnichsen N, Reinicke C, Herrmann C, Glatzel E. [Zinc therapy of alopecia areata]. Dermatologische Monatschrift. 1984;170(7):437-442.

Sonti S, Makino ET, Garruto JA, Gruber JV, Rao S, Mehta RC. Efficacy of a novel treatment serum in the improvement of photodamaged skin. Int J Cosmet Sci. Apr 2013;35(2):156-162.

Stein PK, Soare A, Meyer TE, Cangemi R, Holloszy JO, Fontana L. Caloric restriction may reverse age-related autonomic decline in humans. Aging Cell. Aug 2012;11(4):644-650.

Steven S, Taylor R. Restoring normoglycaemia by use of a very low calorie diet in long- and short-duration Type 2 diabetes. Diabetic medicine : a journal of the British Diabetic Association. Sep 2015;32(9):1149-1155.

Sudha PN, Rose MH. Beneficial effects of hyaluronic acid. Advances in food and nutrition research. 2014;72:137-176.

Suman T. Enhancing facial esthetics by other modalities. International journal of dentistry. 2011;2011:513957.

Surette ME. The science behind dietary omega-3 fatty acids. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne. Jan 15 2008;178(2):177-180.

Surjana D, Halliday GM, Martin AJ, Moloney FJ, Damian DL. Oral nicotinamide reduces actinic keratoses in phase II double-blinded randomized controlled trials. The Journal of investigative dermatology. May 2012;132(5):1497-1500.

Ting W. Tretinoin for the treatment of photodamaged skin. Cutis. Jul 2010;86(1):47-52.

Traikovich SS. Use of topical ascorbic acid and its effects on photodamaged skin topography. Archives of otolaryngology--head & neck surgery. Oct 1999;125(10):1091-1098.

Trookman NS, Rizer RL, Ford R, Ho E, Gotz V. Immediate and Long-term Clinical Benefits of a Topical Treatment for Facial Lines and Wrinkles. The Journal of clinical and aesthetic dermatology. Mar 2009;2(3):38-43.

Trüeb RM. Pharmacologic interventions in aging hair. Clinical interventions in aging. 06/2006;1(2):121-129.

Uitto J. The role of elastin and collagen in cutaneous aging: intrinsic aging versus photoexposure. Journal of drugs in dermatology : JDD. Feb 2008;7(2 Suppl):s12-16.

UMMC. University of Maryland Medical Center. Facial Plastic Surgery. Factors Affecting Our Skin. Copyright 2016. Accessed 9/13/2016.

Urbanska M, Nowak G, Florek E. [Cigarette smoking and its influence on skin aging]. Przeglad lekarski. 2012;69(10):1111-1114.

Vantage. Vantage Specialty Ingredients. Hylasome EG-10 Accessed 9/13/2016.

Vierkotter A, Schikowski T, Ranft U, Sugiri D, Matsui M, Kramer U, Krutmann J. Airborne particle exposure and extrinsic skin aging. The Journal of investigative dermatology. Dec 2010;130(12):2719-2726.

Wang Y, Zuo M. Nicotinamide improves sevoflurane-induced cognitive impairment through suppression of inflammation and anti-apoptosis in rat. International journal of clinical and experimental medicine. 2015;8(11):20079-20085.

Wing RR, Blair EH, Bononi P, Marcus MD, Watanabe R, Bergman RN. Caloric restriction per se is a significant factor in improvements in glycemic control and insulin sensitivity during weight loss in obese NIDDM patients. Diabetes care. Jan 1994;17(1):30-36.

Winkelmann RR, Del Rosso J, Rigel DS. Polypodium leucotomos extract: a status report on clinical efficacy and safety. Journal of drugs in dermatology: JDD. Mar 2015;14(3):254-261.

Wolowa F, Stachow A. [Zinc sulfate in the treatment of alopecia areata]. Przeglad dermatologiczny. Nov-Dec 1978;65(6):687-696.

Yiasemides E, Sivapirabu G, Halliday GM, Park J, Damian DL. Oral nicotinamide protects against ultraviolet radiation-induced immunosuppression in humans. Carcinogenesis. Jan 2009;30(1):101-105.

Yuksel EP, Sahin G, Aydin F, Senturk N, Turanli AY. Evaluation of effects of platelet-rich plasma on human facial skin. Journal of cosmetic and laser therapy: official publication of the European Society for Laser Dermatology. Oct 2014;16(5):206-208.

Yusuf N, Irby C, Katiyar SK, Elmets CA. Photoprotective effects of green tea polyphenols. Photodermatology, photoimmunology & photomedicine. Feb 2007;23(1):48-56.

Zhang S, Dong Z, Peng Z, Lu F. Anti-aging effect of adipose-derived stem cells in a mouse model of skin aging induced by D-galactose. PloS one. 2014;9(5):e97573.

Zouboulis CC, Adjaye J, Akamatsu H, Moe-Behrens G, Niemann C. Human skin stem cells and the ageing process. Experimental gerontology. Nov 2008;43(11):986-997.