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50 mg, 60 capsules
Item# 00882

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$14.25 Save 25%


Supports healthy hormone balance and whole-body health

50 mg, 60 capsules
Item# 00882

Retail Price: $19.00

Your Price: $14.25 Save 25%

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  • DHEA
  • 50 mg, 60 capsules
  • Item Catalog Number: 00882

DHEA is the body’s most abundant circulating hormone, but as we age DHEA levels begin to decline. Supplementing for healthy DHEA levels can help support immune function, circulatory health, mood and well-being, healthy body weight and lean muscle mass, libido, and more.

Benefits at a Glance

  • Maintains youthful DHEA hormone balance
  • Encourages healthy immune function and circulation
  • Promotes a healthy body weight and lean muscle mass
  • Supports healthy mood, libido, well-being, and more

More about DHEA

Peak blood levels of DHEA occur at approximately age 25, decreasing progressively thereafter.1 Maintaining healthy, youthful serum levels of DHEA has a variety of health benfits.1-4 Thousands of studies have been published on DHEA's various benefits, including immunomodulatory properties as well as positive effects on mood, quality of life, and body composition. Rejuvenating the circulating levels of DHEA to those found in young people may improve overall well-being and sexual function as well.

Body composition, mood, and more

In a randomized, double-blind, placebo-controlled study, ten months of DHEA supplementation showed enhanced increases in muscle mass and strength resulting from resistance exercise in elderly individuals.4 Other studies of DHEA regimens in women suggest beneficial effects on well-being, mood, and sexuality.5 Studies show DHEA may improve mood and alleviate melancholy,6 and may also benefit the aging brain.7-9

Cardio, circulatory, and structural health

DHEA has the capacity to improve vascular health by a number of complex processes.10-12 One of them is increasing nitric oxide synthesis.10 DHEA has also been shown to support a healthy circulatory system and joint/bone health.10-14 In a randomized, double-blind, controlled trial, one year of DHEA supplementation helped protect hip bone mineral density in older adults and spine bone mineral density in older women.15

DHEA usage and safety precautions

Life Extension's DHEA directions for use are specially drafted to provide safe, optimal dosing. Regular blood testing is highly recommended both for dosage accuracy and blood level monitoring. Because of the overwhelming evidence connecting low levels of DHEA to age-related factors, Life Extension suggests that all people over age 40 begin DHEA supplementation.

For most people, the starting dose of DHEA is between 15–75 mg, taken in one daily dose. People over age 40 who do not supplement with DHEA usually have serum levels below 200 µg/dL, and many are below 100 µg/dL since an age-related decline generally takes place after the third decade in life.1,16 This product contains 50 mg of DHEA per capsule.

DHEA precautions for men

Men with prostate cancer or severe benign prostate disease are advised to avoid DHEA since it can be converted into testosterone (and estrogen). Therefore, men are advised to have a PSA and digital rectal exam before initiating DHEA to rule out existing prostate disease.

It is important for men over 40 to have a physician check their PSA and DHEA-S serum levels every six to twelve months. Men should also periodically check their blood levels for free testosterone and estrogen to make sure that DHEA is following a youthful metabolic pathway.

DHEA precautions for women

Women should consider estrogen and testosterone testing when they take their DHEA blood test in order to evaluate DHEA's effect on their blood levels of these hormones. Women who have been diagnosed with an estrogen-dependent cancer should consult their physicians before beginning the DHEA restoration process.

  1. Clin Chim Acta. 2004 Mar;341(1-2):1-15.
  2. J Clin Endocrinol Metab. 1992 Oct;75(4):1002-4.
  3. J Clin Endocrinol Metab. 1997 Aug;82(8):2396-402.
  4. Am J Physiol Endocrinol Metab. 2006 Nov;291(5):E1003-8.
  5. Maturitas.2010 Jun;66(2):172-9.
  6. Psychopharmacology (Berl). 2006 Nov;188(4):541-51.
  7. Front Neuroendocrinol.2009 Jan;30(1):65-91.
  8. Biogerontology. 2008 Aug;9(4):235-46.
  9. Ann N Y Acad Sci. 2006 Nov;1088:139-52.
  10. Pharmacol Ther. 2010 May;126(2):186-99. 
  11. Circulation. 2009 Sep 29;120(13):1231-40.
  12. Atherosclerosis. 2009 Sep;206(1):77-85. 
  13. Clin Endocrinol (Oxf). 2006 Mar;64(3):260-4.
  14. Clin Chim Acta.2009 Oct;408(1-2):1-7. 
  15. J Clin Endocrinol Metab. 2006 Aug;91(8):2986-93.
  16. J Endocrinol. 1999 Oct;163(1):1-5.


Supplement Facts

Serving Size 1 capsule

Amount Per Serving

Dehydroepiandrosterone (DHEA)

50 mg

Other ingredients: microcrystalline cellulose, gelatin, silica.


Dosage and Use
  • The exact number of capsules to be taken should be determined by blood testing and the advice of a physician.
  • For optimal results, take one (1) to two (2) capsules in the morning.
  • DHEA serum blood tests are suggested 3 to 6 weeks after initiating DHEA replacement therapy to optimize individual dosing.

Consult a physician or licensed qualified health care professional before using this product if you have, or have a family history of breast cancer, prostate cancer, or other hormone-sensitive diseases.



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