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DNA Genetic Cancer Risk Profile


Item# LC100057

Your Price:
$299.00 Save 25%

DNA Genetic Cancer Risk Profile

Examines 98 genes for mutations associated with 25 hereditary cancers


Item# LC100057

Retail Price: $398.66

Your Price: $299.00 Save 25%

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Description

  • DNA Genetic Cancer Risk Profile
  • Item Catalog Number: LC100057

With only a saliva sample, you can identify your risk for these 25 hereditary cancers by analyzing 98 genes from your DNA.


Breast

Ovaries

Endometrium, Uterine

Myometrium, Uterine

Prostate Gland

Stomach

Large Bowel and Rectum (Colon)

Lung and Pleura

Small Intestines

Esophagus

Urinary Tract and Bladder

Exocrine Pancreas

Endocrine Pancreas

Kidneys

Cervix

Skin

Bone

Thyroid Gland

Liver

Soft Tissue

Miscellaneous Endocrine Glands

Blood

Head and Neck

Central Nervous System

Peripheral Nervous System

 


Gene Matrix

This DNA test is a cutting-edge, breakthrough clinical test for inherited cancer risk:

  • It is accurate, finally affordable and actionable
  • It's advanced next-gen-sequencing technology is clinically validated and highly accurate
  • It covers all American College of Medical Genetics and Genomics (ACMG) and National Comprehensive Cancer Network (NCCN) guideline recommended genes
  • Samples are processed by CellMax, a CLIA certified laboratory

Sample Report

Cancer can be connected to your DNA – that is, cancer is often caused by certain changes to genes that control the way your cells function, especially how they grow and divide. These changes include mutations in your DNA.

Genetic mutations associated with increased cancer risk can be passed from parents to their children. These inherited abnormal genes are in contrast to acquired mutations, which occur over time and include environmental factors and lifestyle choices such as smoking or sun exposure.

Inherited genetic mutations play a major role in about 5 to 10% of all cancers.1 People with certain genetic mutations may have an increased risk of manifesting hereditary cancers up to 20 times greater than individuals without these mutations.2-5

Those who inherit mutated genes associated with cancer not only have a greater risk of getting hereditary cancer, the cancer tends to appear earlier in their lifetime— and their cancer is usually more aggressive.

BRCA1 and BRCA2 are two widely recognized genes known to increase the risk of breast and ovarian cancers, as well as prostate cancer, pancreatic cancer, and male breast cancer. However, many other genes can also influence your risk of developing cancer.

According to the U.S. National Cancer Institute, about 4 in 10 people in the United States will get cancer in their lifetime2. Cancer continues to be the second leading cause of death in the U.S., and the number of cases of cancer worldwide is projected to increase by 70 percent in the next two decades.6

Understanding your risk for hereditary cancer is a major step in taking charge of your health so you can proactively change the expression of your genes through lifestyle, diet, supplements, exercise, and even your outlook. Armed with the knowledge of your genetic mutations, you can:

  • Develop personalized cancer risk management strategies
  • Understand your risk for a second or new cancer and make informed medical decisions with your doctor

Genetic risk is about probability, not certainty. Having genetic mutations does not mean that you will get cancer it just means that you may need to work harder to lower your risk than people who do not have the mutation. One of the greatest benefits of genetic testing is knowing you have a mutation and having access to a personalized health risk management program. This can help prevent or find cancer at an earlier stage when it is most treatable.

Instructions

This test is conveniently packaged as a kit. You will collect a saliva sample at home to ship directly to the laboratory in a pre-paid mailing envelope. Instructions for easy collection are included. Take all medications as prescribed and do not eat, drink, smoke, chew gum, floss, or brush your teeth for 30 minutes prior to the saliva collection.

Note

Results take 3-4 weeks from when specimen is received. This test is not available in Pennsylvania, Maryland, New York, and Rhode Island. Since genetic mutations do not change over time, each person needs to be tested only once in their lifetime.

References

  1. https://www.cancer.gov/about-cancer/causes-prevention/genetics
  2. https://www.cancer.gov/about-cancer/causes-prevention/genetics/brca-fact-sheet
  3. https://www.ncbi.nlm.nih.gov/pubmed/23628597
  4. https://www.ncbi.nlm.nih.gov/pubmed/20301390
  5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3693757/
  6. https://www.cancer.gov/about-cancer/understanding/statistics

The laboratory services are for informational purposes only. It is not the intention of National Diagnostics, Inc and Life Extension to provide specific medical advice but rather to provide users with information to better understand their health. Specific medical advice including diagnosis and treatment will not be provided. Always seek the advice of a trained health professional for medical advice, diagnosis or treatment.

Both the physician and the testing laboratory are independent contractors with whom National Diagnostics, Inc makes arrangements for your blood tests. Neither National Diagnostics, Inc or Life Extension will be liable for any acts or omissions of the physician, the testing laboratory, or their agents or employees.

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