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Reports from University of Belgrade Highlight Recent Research in Calcified Tissue Research


By a News Reporter-Staff News Editor at Cardiovascular Week -- Current study results on Calcified Tissue Research have been published. According to news reporting from Belgrade, Serbia, by NewsRx journalists, research stated, "Osteoporosis and hypertension are two frequent diseases among the aging population that share a similar etiopathology and often coexist. Moreover, treatment of hypertension affects bone mineral density and, therefore, can worsen osteoporosis."

The news correspondents obtained a quote from the research from the University of Belgrade, "This narrative review considers the influence of the main etiologic factors that contribute to the development of hypertension and osteoporosis and examines the effect of the most often used antihypertensives on bones. A computerized literature search of relevant English publications regarding the etiology of hypertension and osteoporosis as well as the impact of antihypertensives on osteoporosis from 1996 to 2011 was completed in October 2011. The latest update in the search was performed from May to June 2012. The most relevant nongenetic factors in the etiology of osteoporosis and hypertension are low calcium intake, vitamin D and vitamin K deficiency, high consumption of sodium salt, and the effects of different forms of nitric oxide. Thiazide diuretics are the only antihypertensives that have a positive influence on bone mineral density. For other antihypertensive drugs, the data are conflicting, indicating that they may have a potentially negative or positive influence on bone mineral density and fracture risk reduction. Some studies did not find a correlation between the use of antihypertensives and bone mineral density."

According to the news reporters, the research concluded: "Due to the frequent coexistence of hypertension and osteoporosis, when selecting long-term antihypertensive therapy the potential effects of antihypertensive drugs on development, worsening, or improvement of osteoporosis should also be considered."

For more information on this research see: The Relationship Among Hypertension, Antihypertensive Medications, and Osteoporosis: A Narrative Review. Calcified Tissue International, 2013;92(3):217-227. Calcified Tissue International can be contacted at: Springer, 233 Spring St, New York, NY 10013, USA. (Springer -; Calcified Tissue International -

Our news journalists report that additional information may be obtained by contacting K. Ilic, University of Belgrade, Fac Med, Inst Rheumatol, Belgrade 11221, Serbia (see also Calcified Tissue Research).

Keywords for this news article include: Serbia, Europe, Belgrade, Hypertension, Osteoporosis, Bone Research, Cardiovascular Diseases, Metabolic Bone Diseases, Calcified Tissue Research

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