Findings from Harvard University Provides New Data about Adenomas
By a News Reporter-Staff News Editor at Gastroenterology Week -- Investigators publish new report on Adenomas. According to news reporting from Boston, Massachusetts, by NewsRx journalists, research stated, "Carotenoids have been hypothesized to prevent carcinogenesis through their antioxidant and pro-vitamin A properties. We examined associations between intakes of specific carotenoids and risk of colorectal adenomas."
The news correspondents obtained a quote from the research from Harvard University, "Among 29,363 men who reported having a lower bowel endoscopy between 1986 and 2006, 3,997 cases of colorectal adenoma were identified in the Health Professionals Follow-up Study. Participants completed food frequency questionnaires every 4 years; dietary information was cumulatively updated. The associations between carotenoid intakes and risk of colorectal adenomas overall and by anatomic site, stage, smoking status and alcohol consumption were investigated using multivariate logistic regression models. Total beta-carotene and dietary beta-carotene, lycopene and lutein/zeaxanthin intakes and the total carotenoid score were inversely associated with colorectal adenoma risk. The odds ratios (95 % confidence intervals) comparing the highest versus lowest quintile of intake were 0.78 (0.69-0.88) for total beta-carotene, 0.72 (0.64-0.81) for dietary beta-carotene, 0.83 (0.74-0.93) for lycopene, 0.86 (0.76-0.96) for lutein/zeaxanthin, and 0.87 (0.77-0.97) for the total carotenoid score. Associations for alpha-carotene and beta-cryptoxanthin intakes were null. We did not find significant differences in the associations between intakes of each carotenoid and risk of colorectal adenoma by anatomic site or stage (all p values, test for common effects > 0.10). The inverse associations we observed for total beta-carotene and dietary beta-carotene, lycopene, and lutein/zeaxanthin intakes and the total carotenoid score with adenoma risk also did not vary by smoking status and alcohol consumption."
According to the news reporters, the research concluded: "This study found that a diet high in carotenoids was associated with a reduced risk of colorectal adenomas."
For more information on this research see: Carotenoid intake and risk of colorectal adenomas in a cohort of male health professionals. Cancer Causes & Control, 2013;24(4):705-717. Cancer Causes & Control can be contacted at: Springer, Van Godewijckstraat 30, 3311 Gz Dordrecht, Netherlands (see also Adenomas).
Our news journalists report that additional information may be obtained by contacting S. Jung, Harvard University, Sch Public Hlth, Dept. of Biostat, Boston, MA 02115, United States.
Keywords for this news article include: Boston, Lutein, Alkenes, Polyenes, Terpenes, Colorectal, Carotenoids, Cyclohexanes, Cyclohexenes, Hydrocarbons, Xanthophylls, Massachusetts, United States, Endocrinology, beta Carotene, Cycloparaffins, Gastroenterology, Organic Chemicals, Biological Pigments, Risk and Prevention, North and Central America
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