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Report Summarizes Medical Research Study Findings from A. Tincani and Co-Researchers


By a News Reporter-Staff News Editor at Genomics & Genetics Weekly -- A new study on Medical Research is now available. According to news reporting originating in Brescia, Italy, by NewsRx journalists, research stated, "Sjogren's syndrome (SS) is a systemic progressive autoimmune disease characterized by a complex pathogenesis requiring a predisposing genetic background and involving immune cell activation and autoantibody production. The immune response is directed to the exocrine glands, causing the typical 'sicca syndrome', but major organ involvement is also often seen."

The news reporters obtained a quote from the research, "The etiology of the disease is unknown. Infections could play a pivotal role: compared to normal subjects, patients with SS displayed higher titers of anti-Epstein-Barr virus (EBV) early antigens, but lower titers of other infectious agent antibodies such as rubella and cytomegalovirus (CMV) suggest that some infections may have a protective role against the development of autoimmune disease. Recent findings seem to show that low vitamin D levels in patients with SS could be associated with severe complications such as lymphoma and peripheral neuropathy. This could open new insights into the disease etiology. The current treatments for SS range from symptomatic therapies to systemic immunosuppressive drugs, especially B cell-targeted drugs in cases of organ involvement."

According to the news reporters, the research concluded: "Vitamin D supplementation may be an additional tool for optimization of SS treatment."

For more information on this research see: Novel aspects of Sjogren's syndrome in 2012. Bmc Medicine, 2013;11():93. (BioMed Central -; Bmc Medicine -

Our news correspondents report that additional information may be obtained by contacting A. Tincani, Rheumatology and Clinical Immunology Unit, Spedali Civili, Piazzale Spedali Civili 1, 25100 Brescia, Italy (see also Medical Research).

Keywords for this news article include: Italy, Europe, Brescia, Genetics, Medical Research, Sjogren's Syndrome.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2013, NewsRx LLC

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