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Findings on C Reactive Protein Reported by Investigators at University of Montreal


By a News Reporter-Staff News Editor at Proteomics Weekly -- Data detailed on C Reactive Protein have been presented. According to news reporting out of Montreal, Canada, by NewsRx editors, research stated, "Increasing evidence suggests that high-sensitivity C-reactive protein (hs-CRP) is associated with cardiometabolic risk factors (CMRF) while being also related to micronutrient deficiencies. As part of a project on the double burden of under-and overnutrition in sub-Saharan Africa, we assessed the relationship between hs-CRP and both CMRF and micronutrient deficiencies in a population-based cross-sectional study carried out in the Northern district of Ouagadougou, the capital city of Burkina Faso."

Our news journalists obtained a quote from the research from the University of Montreal, "We randomly selected 330 households stratified by income tertile. In each income stratum, 110 individuals aged 25-60 years and having lived in Ouagadougou for at least 6 months were randomly selected, and underwent anthropometric measurements and blood sample collection. The prevalence of high hs-CRP was 39.4%, with no sex difference. Vitamin A-deficient subjects (12.7%) exhibited significant risk of elevated hs-CRP (OR 2.5; P = 0.015). Serum ferritin was positively correlated with log hs-CRP (r 0.194; P = 0.002). The risk of elevated hs-CRP was significant in subjects with BMI >= 25 kg/m(2) (OR 6.9; 95% CI 3.6, 13.3), abdominal obesity (OR 4.6; 95% CI 2.2, 7.3) and high body fat (OR 10.2; 95% CI 5.1, 20.3) (P < 0.001, respectively). Independent predictors of hs-CRP in linear regression models were waist circumference (beta = 0.306; P = 0.018) and serum TAG (beta = 0.158; P = 0.027). In this sub-Saharan population, hs-CRP was consistently associated with adiposity."

According to the news editors, the research concluded: "Assuming that plasma hs-CRP reflects future risk of cardiovascular events, intervention which reduces CRP, or chronic and acute nutrition conditions associated with it, could be effective in preventing their occurrence particularly in sub-Saharan Africa."

For more information on this research see: Association of high-sensitivity C-reactive protein with cardiometabolic risk factors and micronutrient deficiencies in adults of Ouagadougou, Burkina Faso. British Journal of Nutrition, 2013;109(7):1266-1275. British Journal of Nutrition can be contacted at: Cambridge Univ Press, Edinburgh Bldg, Shaftesbury Rd, CB2 8RU Cambridge, England. (Cambridge University Press -; British Journal of Nutrition -

Our news journalists report that additional information may be obtained by contacting A.N. Zeba, University of Montreal, Center Hosp Univ Montreal, Dept. of Med, Montreal, PQ H2L 4M1, Canada (see also C Reactive Protein).

Keywords for this news article include: Quebec, Canada, Montreal, Albumins, Immunology, Proteomics, Immunoproteins, C Reactive Protein, C-Reactive Protein, Risk and Prevention, Acute-Phase Proteins, North and Central America

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