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New Weight Loss Findings Has Been Reported by Investigators at University of Tehran


By a News Reporter-Staff News Editor at Obesity & Diabetes Week -- Data detailed on Weight Loss have been presented. According to news originating from Tehran, Iran, by NewsRx correspondents, research stated, "Obesity is associated with low-grade systemic inflammation which has been linked to the increased risk of cardiovascular disease and Type 2 diabetes in obese patients. To evaluate changes in pro/anti-inflammatory adipocytokines and metabolic profile after moderate diet-induced weight loss."

Our news journalists obtained a quote from the research from the University of Tehran, "Twenty-nine pre-menopausal obese women (body mass index >= 30 kg/m(2)) aged 21 to 54 years without diabetes, hypertension, or hyperlipidemia, were enrolled in this study. We measured anthropometric parameters, lipid and glucose profiles, interleukin (IL)-6, IL-10, and IL-18 in obese women, who then entered a medically supervised program aimed at reducing body weight by 10% or more. Obese women restricted their caloric intake (by 500-1000 kcal/day) and consumed 50 g/day of a fiber supplement (Slim Last Powder) for 12 weeks. By completing the dietary intervention program, weight (Delta=-10.0%, p<0.0001), body mass index, waist circumference, triceps skinfold thickness, total cholesterol, triglyceride, and fasting plasma glucose significantly decreased, while HDL-cholesterol significantly increased. While plasma levels of IL-6 and IL-18 decreased by 27% after 12 weeks, no significant change was observed in circulating levels of IL-10. Our study suggests that an improved body composition induced by restriction of energy intake is associated with favorable serum concentrations of IL-6 and IL-18 in obese women."

According to the news editors, the research concluded: "However, the anti-inflammatory IL-10 is not affected by a moderate weight decrease."

For more information on this research see: Effect of diet-induced weight loss on inflammatory cytokines in obese women. Journal of Endocrinological Investigation, 2013;36(4):211-215. Journal of Endocrinological Investigation can be contacted at: Editrice Kurtis S R L, Via Luigi Zoja 30, 20153 Milan, Italy (see also Weight Loss).

The news correspondents report that additional information may be obtained from N. Tajik, Univ Tehran Med Sci, Sch Public Hlth, Dept. of Epidemiol & Biostat, Tehran 141556446, Iran.

Keywords for this news article include: Iran, Asia, Tehran, Obesity, Diabetes, Cytokines, Bariatrics, Weight Loss

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