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Reports from Bose Institute Add New Data to Findings in Diabetes


By a News Reporter-Staff News Editor at Gastroenterology Week -- Current study results on Diabetes have been published. According to news reporting from Bengal, India, by NewsRx journalists, research stated, "Diabetic complications associated with increased oxidative stress can be suppressed by antioxidants. In the present study we investigated the antidiabetic and antioxidant effects of Kombucha (KT), a fermented black tea, in comparison to that of unfermented black tea (BT), in ALX-induced diabetic rats."

The news correspondents obtained a quote from the research from Bose Institute, "ALX exposure lowered the body weight and plasma insulin by about 28.12% and 61.34% respectively and elevated blood glucose level and glycated Hb by about 3.79 and 3.73 folds respectively. The oxidative stress related parameters like lipid peroxidation end products (increased by 3.38, 1.7, 1.65, 1.94 folds respectively), protein carbonyl content (increased by 2.5, 2.35, 1.8, 3.26 folds respectively), glutathione content (decreased by 59.8%, 47.27%, 53.69%, 74.03% respectively), antioxidant enzyme activities were also altered in the pancreatic, hepatic, renal and cardiac tissues of diabetic animals. Results showed significant antidiabetic potential of the fermented beverage (150 mg lyophilized extract/kg bw for 14 days) as it effectively restored ALX-induced pathophysiological changes. Moreover, it could ameliorate DNA fragmentation and caspase-3 activation in the pancreatic tissue of diabetic rats. Although unfermented black tea is effective in the above pathophysiology, KT was found to be more efficient."

According to the news reporters, the research concluded: "This might be due to the formation of some antioxidant molecules during fermentation period."

For more information on this research see: Effect of Kombucha, a fermented black tea in attenuating oxidative stress mediated tissue damage in alloxan induced diabetic rats. Food and Chemical Toxicology, 2013;60():328-340. Food and Chemical Toxicology can be contacted at: Pergamon-Elsevier Science Ltd, The Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, England. (Elsevier -; Food and Chemical Toxicology -

Our news journalists report that additional information may be obtained by contacting S. Bhattacharya, Bose Inst, Div Mol Med, Kolkata 700054, W Bengal, India. Additional authors for this research include R. Gachhui and P.C. Sil (see also Diabetes).

Keywords for this news article include: Asia, Antioxidants, India, Bengal, Diabetes, Endocrinology, Protective Agents

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2013, NewsRx LLC

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