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Investigators from Delft University of Technology Zero in on Geriatrics


By a News Reporter-Staff News Editor at Clinical Trials Week -- Investigators publish new report on Aging Research. According to news reporting originating in Delft, Netherlands, by NewsRx journalists, research stated, "ObjectivesTo investigate whether serum 25-hydroxy vitamin D (25(OH)D) is associated with physical performance in men and women. DesignCross-sectional. SettingEmergency departments (EDs) of five hospitals."

The news reporters obtained a quote from the research from the Delft University of Technology, "ParticipantsOlder adults who visited an ED because of a fall (Na6). MeasurementsPhysical performance was assessed using the Timed Up and Go Test, the Five Time Sit to Stand Test, handgrip strength, and the tandem stand test. Multivariate linear regression was used to assess the association between physical performance and log-transformed 25(OH)D concentration adjusted for potential confounders. ResultsIn men, higher serum 25(OH)D concentration was significantly associated with better handgrip strength (regression coefficient (B)=3.86, 95% confidence interval (CI)=2.04-5.69), faster TUG time (B=-2.82, 95% CI=-4.91 to -0.73), and faster FTSS time (B=-3.39, 95% CI=-5.67 to -1.11). In women, higher serum 25(OH)D concentration was significantly associated with faster TUG time (B=-2.68, 95% CI=-4.87 to -0.49). ConclusionA positive association was found between serum 25(OH)D level and physical performance in men and women."

According to the news reporters, the research concluded: "Intervention studies are needed of vitamin D-deficient older men and women to further investigate the effect of vitamin D supplementation in this group."

For more information on this research see: Vitamin D and Physical Performance in Older Men and Women Visiting the Emergency Department Because of a Fall: Data from the Improving Medication Prescribing to reduce Risk Of FALLs (IMPROveFALL) Study. Journal of the American Geriatrics Society, 2013;61(11):1948-1952. Journal of the American Geriatrics Society can be contacted at: Wiley-Blackwell, 111 River St, Hoboken 07030-5774, NJ, USA. (Wiley-Blackwell -; Journal of the American Geriatrics Society -

Our news correspondents report that additional information may be obtained by contacting N.D.A. Boye, Delft University of Technology, Fac Ind Design Engn, Delft, Netherlands. Additional authors for this research include C. Oudshoorn, N. van der Velde, E.M.M. van Lieshout, O.J. de Vries, P. Lips, E.F. van Beeck, P. Patka and T.J.M. van der Cammen (see also Aging Research).

Keywords for this news article include: Delft, Europe, Netherlands, Aging Research, Clinical Trials and Studies

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