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New Neutral Amino Acids Findings from Shaare Zedek Medical Center Described


By a News Reporter-Staff News Editor at Clinical Trials Week -- New research on Neutral Amino Acids is the subject of a report. According to news reporting originating from Jerusalem, Israel, by NewsRx correspondents, research stated, "Many cancer patients are using non-herbal nutritional supplements (NHNS), often without informing their oncologists. To review the literature and summarize the beneficial effects and safety of NHNS in the prevention and reduction of treatment-related symptoms."

Our news editors obtained a quote from the research from Shaare Zedek Medical Center, "Databases were searched for randomized, controlled clinical trials (Jadad score >= 2) using AltHealthWatch, Cochrane Database of Systematic Reviews, Embase, MEDLINE, Memorial Sloan-Kettering Integrative Medicine Service Database, Natural Standard Database, and PubMed. The key words searched were the following: alternative and/or complementary medicine, nutritional and/or dietary supplements, quality of life, symptoms and/or side effects, specific toxicities (e. g., neuropathy, mucositis), and specific supplements (e. g., vitamin E, glutamine, etc.). A number of NHNS products were found to be effective. The incidence and severity of peripheral sensory neuropathy associated with taxane-agents such as paclitaxel can be reduced with vitamin E, glutamine, and acetyl-L-carnitine. Vitamin E and glutamine also have been shown to reduce oral mucositis resulting from radiation and chemotherapy, and glutamine and probiotics can reduce chemotherapy-induced diarrhea. There is a need to develop an open and nonjudgmental dialogue between oncologists and cancer patients, addressing the needs of the patient while dealing with issues related to the efficacy and safety of these products."

According to the news editors, the research concluded: "Referral of patients to an integrative medicine consultant may help achieve these goals, providing both parties with the option of reaching an informed and respectful decision about treatment."

For more information on this research see: Advising Patients on the Use of Non-Herbal Nutritional Supplements During Cancer Therapy: A Need for Doctor-Patient Communication. Journal of Pain and Symptom Management, 2013;46(6):887-896. Journal of Pain and Symptom Management can be contacted at: Elsevier Science Inc, 360 Park Ave South, New York, NY 10010-1710, USA. (Elsevier -; Journal of Pain and Symptom Management -

The news editors report that additional information may be obtained by contacting E. Ben-Arye, Shaare Zedek Med Center, Center Integrat Complementary Med, Jerusalem, Israel. Additional authors for this research include A. Polliack, E. Schiff, T. Tadmor and N. Samuels (see also Neutral Amino Acids).

Keywords for this news article include: Asia, Drugs, Israel, Cancer, Oncology, Jerusalem, Glutamine, Treatment, Chemotherapy, Basic Amino Acids, Diamino Amino Acids, Neutral Amino Acids, Clinical Trials and Studies

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