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Findings from University of Illinois Provides New Data on Weight Loss


By a News Reporter-Staff News Editor at Clinical Trials Week -- Research findings on Weight Loss are discussed in a new report. According to news reporting originating in Chicago, Illinois, by NewsRx journalists, research stated, "Alternate day fasting (ADF; ad libitum 'feed day', alternated with 25% energy intake 'fast day'), is effective for weight loss and cardio-protection in obese individuals. Whether these effects occur in normal weight and overweight individuals remains unknown."

The news reporters obtained a quote from the research from the University of Illinois, "This study examined the effect of ADF on body weight and coronary heart disease risk in non-obese subjects. Thirty-two subjects (BMI 20-29.9 kg/m(2)) were randomized to either an ADF group or a control group for 12 weeks. Body weight decreased (P < 0.001) by 5.2 +/- 0.9 kg (6.5 +/- 1.0%) in the ADF group, relative to the control group, by week 12. Fat mass was reduced (P < 0.001) by 3.6 +/- 0.7 kg, and fat free mass did not change, versus controls. Triacylglycerol concentrations decreased (20 +/- 8%, P< 0.05) and LDL particle size increased (4 +/- 1 angstrom, P< 0.01) in the ADF group relative to controls. CRP decreased (13 +/- 17%, P< 0.05) in the ADF group relative to controls at week 12. Plasma adiponectin increased (6 +/- 10%, P< 0.01) while leptin decreased (40 +/- 7%, P< 0.05) in the ADF group versus controls by the end of the study. LDL cholesterol, HDL cholesterol, homocysteine and resistin concentrations remained unchanged after 12 weeks of treatment."

According to the news reporters, the research concluded: "These findings suggest that ADF is effective for weight loss and cardio-protection in normal weight and overweight adults, though further research implementing larger sample sizes is required before solid conclusion can be reached."

For more information on this research see: Alternate day fasting for weight loss in normal weight and overweight subjects: a randomized controlled trial. Nutrition Journal, 2013;12():1-8. Nutrition Journal can be contacted at: Biomed Central Ltd, 236 Grays Inn Rd, Floor 6, London WC1X 8HL, England. (BioMed Central -; Nutrition Journal -

Our news correspondents report that additional information may be obtained by contacting K.A. Varady, University of Illinois, Dept. of Kinesiol & Nutr, Chicago, IL 60612, United States. Additional authors for this research include S. Bhutani, M.C. Klempel, C.M. Kroeger, J.F. Trepanowski, J.M. Haus, K.K. Hoddy and Y. Calvo (see also Weight Loss).

Keywords for this news article include: Chicago, Illinois, Cardiology, Weight Loss, United States, Heart Disease, Risk and Prevention, North and Central America, Constrictive Pericarditis, Clinical Trials and Studies

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC

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