Texas researcher: Peaches inhibit breast cancer metastasis in mice
Global Data Point
"Cancer cells were implanted under the skin of mice with an aggressive type of breast cancer cells, the MDA-MB-435, and what we saw was an inhibition of a marker gene in the lungs after a few weeks indicating an inhibition of metastasis when the mice were consuming the peach extract," said Dr.
This is very important because it can be translated into something that is also beneficial for people, he added.
This work builds upon previous work at
The previous work as well as the present one was conducted by Cisneros-Zevallos, Dr.
In the western hemisphere, breast cancer is the most common malignant disease for women, he said. In the U.S. last year, the
Most of the complications and high mortality associated with breast cancer are due to metastasis, Cisneros-Zevallos pointed out.
"The importance of our findings are very relevant, because it shows in vivo the effect that natural compounds, in this case the phenolic compounds in peach, have against breast cancer and metastasis. It gives opportunity to include in the diet an additional tool to prevent and fight this terrible disease that affects so many people," he said.
The study was conducted using the peach variety
"In general, peach fruit has chemical compounds that are responsible for killing cancer cells while not affecting normal cells as we reported previously, and now we are seeing that this mixture of compounds can inhibit metastasis," said Cisneros-Zevallos. "We are enthusiastic about the idea that perhaps by consuming only two to three peaches a day we can obtain similar effects in humans. However, this will have to be the next step in the study for its confirmation."
Cisneros-Zevallos continues testing these extracts and compounds in different types of cancer as well as in diabetes studies in vitro and in vivo to understand the molecular mechanisms involved.