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Findings from University of Athens Yields New Data on Diet and Nutrition

Cancer Weekly


By a News Reporter-Staff News Editor at Cancer Weekly -- Research findings on Diet and Nutrition are discussed in a new report. According to news reporting from Athens, Greece, by NewsRx journalists, research stated, "Hepatocellular carcinoma (HCC) has a very poor prognosis and any effort to identify additional risk factors, besides those already established, would be important for the prevention of the disease. Data on the role of diet on HCC risk are still controversial."

The news correspondents obtained a quote from the research from the University of Athens, "We have evaluated the association of adherence to the Mediterranean diet with HCC risk, as well as the interaction of this dietary pattern with chronic hepatitis infection, by combining two case-control studies undertaken in Italy and Greece, including overall 518 cases of HCC and 772 controls. Adherence to the traditional Mediterranean diet was assessed through the Mediterranean diet score (MDS), which ranges between 0 (lowest adherence) and 9 (highest adherence). Odds ratios (OR) for HCC were obtained through multiple logistic regression models, controlling for potentially confounding factors, including chronic infection with hepatitis B/C viruses. Compared to MDS of 0-3, the ORs for HCC were 0.66 (95% confidence interval (CI), 0.41-1.04) for MDS equal to 4 and 0.51 (95% CI, 0.34-0.75) for MDS >= 5, with a significant trend (p <0.001). The detrimental effect of poor adherence to Mediterranean diet on HCC risk was disproportionally high among those chronically infected with hepatitis B and/or C viruses, with a suggestion of super-additive interaction, albeit statistically nonsignificant. Closer adherence to the Mediterranean diet appears to be protective against HCC."

According to the news reporters, the research concluded: "Our results also point to potential benefits from adhering to a Mediterranean dietary pattern for patients chronically infected with hepatitis viruses."

For more information on this research see: Mediterranean diet and hepatocellular carcinoma. Journal of Hepatology, 2014;60(3):606-611. Journal of Hepatology can be contacted at: Elsevier Science Bv, PO Box 211, 1000 Ae Amsterdam, Netherlands. (Elsevier -; Journal of Hepatology -

Our news journalists report that additional information may be obtained by contacting F. Turati, University of Athens, Sch Med, Dept. of Hyg Epidemiol & Med Stat, GR-11527 Athens, Greece. Additional authors for this research include D. Trichopoulos, J. Polesel, F. Bravi, M. Rossi, R. Talamini, S. Franceschi, M. Montella, A. Trichopoulou, C. La Vecchia and P. Lagiou (see also Diet and Nutrition).

Keywords for this news article include: Athens, Greece, Europe, Viruses, Oncology, Virology, Hepatitis, Liver Diseases, Gastroenterology, Diet and Nutrition, Infectious Disease, Mediterranean Diet, Hepatocellular Carcinoma, Digestive System Diseases

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