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Investigators at Department of Ophthalmology Target Cataracts

Clinical Trials Week


By a News Reporter-Staff News Editor at Clinical Trials Week -- A new study on Cataracts is now available. According to news reporting from Guilin, People's Republic of China, by NewsRx journalists, research stated, "Antioxidant vitamins supplements have been suggested as a strategy to decrease the risk of age-related cataract development. However, the results from observational studies and interventional trials of associations between antioxidant vitamins A, C, and E and cataract development have been inconsistent."

The news correspondents obtained a quote from the research from the Department of Ophthalmology, "We aim to evaluate the effectiveness of multivitamin/mineral supplements for decreasing the risk of age-related cataracts by conducting a systematic review and meta-analysis. In September 2013, we searched multiple databases to identify relevant studies including both cohort studies and randomized controlled trials (RCTs). A random-effects model was used to calculate the pooled relative risks (RR) with a 95% confidence interval (CI). Twelve prospective cohort studies and two RCTs were included. Pooled results from the cohort studies indicated that multivitamin/mineral supplements have a significant beneficial effect in decreasing the risk of nuclear cataracts (RR: 0.73; 95% CI: 0.64-0.82), cortical cataracts (RR: 0.81; 95% CI: 0.68-0.94), and any cataracts (RR: 0.66; 95% CI: 0.39-0.93). In addition, there were no decreases in the risk of posterior capsular cataracts (RR: 0.96; 95% CI: 0.72-1.20) or cataract surgery (RR: 1.00; 95% CI: 0.92-1.08). The two RCTs demonstrated that multivitamin/mineral supplements could decrease the risk of nuclear cataracts."

According to the news reporters, the research concluded: "There is sufficient evidence to support the role of dietary multivitamin/mineral supplements for the decreasing the risk of age-related cataracts."

For more information on this research see: The effect of multivitamin/mineral supplements on age-related cataracts: a systematic review and meta-analysis. Nutrients, 2014;6(3):931-49 (see also Cataracts).

Our news journalists report that additional information may be obtained by contacting L.Q. Zhao, Dept. of Ophthalmology, No 181 Hospital of the PLA, No1 Xinqiaoyuan Road, Guilin 541002, People's Republic of China. Additional authors for this research include L.M. Li, H. Zhu and E.Y The Epidemiological Evidence-Based Eye Disease Study Research Group.

Keywords for this news article include: Asia, Guilin, Cataracts, Ophthalmology, People's Republic of China, Clinical Trials and Studies.

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