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Findings on Alzheimer Disease Detailed by Investigators at Ajou University

Pain & Central Nervous System Week


By a News Reporter-Staff News Editor at Pain & Central Nervous System Week -- Investigators publish new report on Neurodegenerative Diseases. According to news reporting from Suwon, South Korea, by NewsRx journalists, research stated, "Oxidative stress is implicated in the pathogenesis of Alzheimer's disease (AD). Accumulating evidence shows that antioxidant-rich food reduces the risk of AD by inhibiting oxidative stress."

The news correspondents obtained a quote from the research from Ajou University, "This study investigates whether serum levels of carotenoids were associated with the risk of AD mortality in a nationally representative sample of US adults. We used data from the Third Nutrition and Health Examination Survey (NHANES III) database and the NHANES III Linked Mortality File. A total of 6,958 participants aged older than 50 years were included in this study. We found that high serum levels of lycopene and lutein+zeaxanthin at baseline were associated with a lower risk of AD mortality after adjustment for potential covariates. The reduction in the mortality risk was progressively raised by increasing serum lycopene (HR = 0.26, 95% CI 0.10-0.69) and lutein+zeaxanthin (HR = 0.43, 95% CI 0.22-0.85) levels. In contrast, no associations with AD mortality were observed for other serum carotenoids, including alpha-carotene, beta-carotene, and beta-cryptoxanthin. High serum levels of lycopene and lutein+zeaxanthin are associated with a lower risk of AD mortality in adults."

According to the news reporters, the research concluded: "Our findings suggest that a high intake of lycopene-or lutein+zeaxanthin-rich food may be important for reducing the AD mortality risk."

For more information on this research see: Serum Lycopene, Lutein and Zeaxanthin, and the Risk of Alzheimer's Disease Mortality in Older Adults. Dementia and Geriatric Cognitive Disorders, 2014;37(3-4):246-256. Dementia and Geriatric Cognitive Disorders can be contacted at: Karger, Allschwilerstrasse 10, Ch-4009 Basel, Switzerland. (Karger -; Dementia and Geriatric Cognitive Disorders -

Our news journalists report that additional information may be obtained by contacting J.Y. Min, Ajou University, Sch Med, Dept. of Occupat & Environm Med, Suwon 443721, South Korea (see also Neurodegenerative Diseases).

Keywords for this news article include: Asia, Suwon, Dementia, South Korea, Tauopathies, Brain Diseases, Alzheimer Disease, Risk and Prevention, Neurodegenerative Diseases, Central Nervous System Diseases

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC

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