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Recent Studies from Sichuan University Add New Data to Clinical Nutrition Research

Health & Medicine Week


By a News Reporter-Staff News Editor at Health & Medicine Week -- Current study results on Diet and Nutrition have been published. According to news originating from Chengdu, People's Republic of China, by NewsRx correspondents, research stated, "Supplementation of fish oil (FO) containing lipid emulsions has been associated with a reduction in the length of hospital stay, infections and liver dysfunction in patients undergoing major surgery. We carried out a meta-analysis and subgroup analysis to examine randomised clinical trial (RCT)-based evidence of the aforementioned effects."

Our news journalists obtained a quote from the research from Sichuan University, "Four databases, reference lists and the WHO ICTRP were systematically searched for RCTs to access the clinical efficacy of fish oil-enriched total parenteral nutrition in post-surgery patients. Methodological quality assessment was based on the Cochrane Handbook and GRADE. Twenty-one RCTs were enrolled for meta-analysis. FO was associated with a significant reduction in the length of hospital stay (mean = -2.14 d, 95% CI = -3.02 to -1.27), infections (OR = 0.53, 95% CI = 0.35-0.81), ALT (mean = -6.35 U/L, 95% CI = -11.75 to 0.94), GGT (mean = -11.01 U/L, 95% Cl = -20.77 to -1.25) and total bilirubin (mean = -2.06 mu mol/L, 95% CI = -3.6 to -0.52), as well as a non-significant change in mortality and postoperative medical cost. The quality of evidence of each clinical outcome was accessed as high. FO-enriched lipid emulsions are likely to reduce infections, the length of hospital stay and liver dysfunction without influencing mortality and may be a safe and preferable choice in post-surgery patients."

According to the news editors, the research concluded: "Further well-designed trials should be performed to determine whether FO lipid emulsions reduce mortality in patients undergoing hepatic surgery, especially liver transplantation, and the cost effectiveness of such treatment."

For more information on this research see: Does intravenous fish oil benefit patients post-surgery? A meta-analysis of randomised controlled trials. Clinical Nutrition, 2014;33(2):226-239. Clinical Nutrition can be contacted at: Churchill Livingstone, Journal Production Dept, Robert Stevenson House, 1-3 Baxters Place, Leith Walk, Edinburgh EH1 3AF, Midlothian, Scotland. (Elsevier -; Clinical Nutrition -

The news correspondents report that additional information may be obtained from N.N. Li, Sichuan University, West China Hosp, Dept. of Gen Surg, Chengdu 610041, People's Republic of China. Additional authors for this research include Y. Zhou, X.P. Qin, Y. Chen, D. He, J.Y. Feng and X.T. Wu (see also Diet and Nutrition).

Keywords for this news article include: Asia, Chengdu, Hospital, Diet and Nutrition, People's Republic of China

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