Studies from Department of Gastroenterology Provide New Data on Lactose Intolerance (Decrease in TSH levels after lactose restriction in Hashimoto's thyroiditis patients with lactose intolerance)
By a News Reporter-Staff News Editor at Gastroenterology Week -- Investigators discuss new findings in Inborn Genetic Diseases and Conditions. According to news reporting originating in Canakkale, Turkey, by NewsRx journalists, research stated, "We aimed to evaluate the prevalence of lactose intolerance (LI) in patients with Hashimoto's thyroiditis (HT) and the effects of lactose restriction on thyroid function in these patients. Eighty-three HT patients taking l-thyroxine (LT4) were enrolled, and lactose tolerance tests were performed on all patients."
The news reporters obtained a quote from the research from the Department of Gastroenterology, "Lactose intolerance was diagnosed in 75.9 % of the patients with HT. Thirty-eight patients with LI were started on a lactose-restricted diet for 8 weeks. Thirty-eight patients with LI (30 euthyroid and 8 with subclinical hypothyroidism), and 12 patients without LI were included in the final analysis. The level of TSH significantly decreased in the euthyroid and subclinical hypothyroid patients with LI [from 2.06 +/- A 1.02 to 1.51 +/- A 1.1 IU/mL and from 5.45 +/- A 0.74 to 2.25 +/- A 1.88 IU/mL, respectively (both P< 0.05)]. However, the level of TSH in patients without LI did not change significantly over the 8 weeks (P > 0.05). Lactose intolerance occurs at a high frequency in HT patients."
According to the news reporters, the research concluded: "Lactose restriction leads to decreased levels of TSH, and LI should be considered in hypothyroid patients who require increasing LT4 doses, have irregular TSH levels and are resistant to LT4 treatment."
For more information on this research see: Decrease in TSH levels after lactose restriction in Hashimoto's thyroiditis patients with lactose intolerance. Endocrine, 2014;46(2):279-284. Endocrine can be contacted at: Humana Press Inc, 999 Riverview Drive Suite 208, Totowa, NJ 07512, USA. (Springer - www.springer.com; Endocrine - www.springerlink.com/content/1355-008x/)
Our news correspondents report that additional information may be obtained by contacting M. Asik, Canakkale Govt Hosp, Dept. of Gastroenterol, Canakkale, Turkey. Additional authors for this research include F. Gunes, E. Binnetoglu, M. Eroglu, N. Bozkurt, H. Sen, E. Akbal, C. Bakar, Y. Beyazit and K. Ukinc (see also Inborn Genetic Diseases and Conditions).
Keywords for this news article include: Turkey, Eurasia, Canakkale, Lactose Intolerance, Hashimoto Thyroiditis, Malabsorption Syndromes, Digestive System Diseases, Gastrointestinal Diseases, Nutritional and Metabolic Diseases, Inborn Errors Carbohydrate Metabolism, Inborn Genetic Diseases and Conditions
Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC