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Studies from Department of Pharmacology & Toxicology Yield New Data on Diet and Nutrition (Masquelier's grape seed extract: from basic flavonoid...

Health & Medicine Week

02-17-17

Studies from Department of Pharmacology & Toxicology Yield New Data on Diet and Nutrition (Masquelier's grape seed extract: from basic flavonoid research to a well-characterized food supplement with health benefits)

By a News Reporter-Staff News Editor at Health & Medicine Week -- Data detailed on Health and Medicine - Diet and Nutrition have been presented. According to news originating from Maastricht, Netherlands, by NewsRx correspondents, research stated, "Careful characterization and standardization of the composition of plant-derived food supplements is essential to establish a cause-effect relationship between the intake of that product and its health effect. In this review we follow a specific grape seed extract containing monomeric and oligomeric flavan-3-ols from its creation by Jack Masquelier in 1947 towards a botanical remedy and nutraceutical with proven health benefits."

Our news journalists obtained a quote from the research from the Department of Pharmacology & Toxicology, "The preparation's research history parallels the advancing insights in the fields of molecular biology, medicine, plant and nutritional sciences during the last 70 years. Analysis of the extract's flavanol composition emerged from unspecific colorimetric assays to precise high performance liquid chromatography - mass spectrometry and proton nuclear magnetic resonance fingerprinting techniques. The early recognition of the preparation's auspicious effects on the permeability of vascular capillaries directed research to unravel the underlying cellular and molecular mechanisms. Recent clinical data revealed a multitude of favorable alterations in the vasculature upon an 8 weeks supplementation which summed up in a health benefit of the extract in healthy humans. Changes in gene expression of inflammatory pathways in the volunteers' leukocytes were suggested to be involved in this benefit."

According to the news editors, the research concluded: "The historically grown scientific evidence for the preparation's health effects paves the way to further elucidate its metabolic fate and molecular action in humans."

For more information on this research see: Masquelier's grape seed extract: from basic flavonoid research to a well-characterized food supplement with health benefits. Nutrition Journal, 2017;16():1-19. Nutrition Journal can be contacted at: Biomed Central Ltd, 236 Grays Inn Rd, Floor 6, London WC1X 8HL, England. (BioMed Central - www.biomedcentral.com/; Nutrition Journal - www.nutritionj.com)

The news correspondents report that additional information may be obtained from A.R. Weseler, Fac Hlth Med & Life Sci, Dept. of Pharmacol & Toxicol, NL-6200 MD Maastricht, Netherlands (see also Health and Medicine - Diet and Nutrition).

Keywords for this news article include: Maastricht, Netherlands, Europe, Diet and Nutrition, Health and Medicine, Food Supplements, Article Review, Department of Pharmacology & Toxicology.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2017, NewsRx LLC

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