Reports from UKK Institute for Health Promotion Research Add New Data to Findings in Geriatrics and Gerontology (A 2-Year Follow-Up After a 2-Year RCT with Vitamin D and Exercise: Effects on Falls, Injurious Falls and Physical Functioning Among ...)
By a News Reporter-Staff News Editor at Clinical Trials Week -- Investigators publish new report on Aging Research - Geriatrics and Gerontology. According to news reporting originating from Tampere, Finland, by NewsRx correspondents, research stated, "Both exercise and vitamin D are recommended means to prevent falls among older adults, but their combined effects on fallinduced injuries are scarcely studied. A 2-year follow-up of a previous 2-year randomized controlled trial with vitamin D and exercise (Ex) of 409 older home-dwelling women using a factorial 2 x 2 design (D(-)Ex(-), D(+)Ex(-), D(-)Ex(+), D(+)Ex(+))."
Our news editors obtained a quote from the research from UKK Institute for Health Promotion Research, "Besides monthly fall diaries, femoral neck bone mineral density (fn-BMD), and physical functioning were assessed at 1 and 2 years after the intervention. After the intervention, S-25OHD concentrations declined to baseline levels in both supplement groups. The groups did not differ for change in fn-BMD or physical functioning, except for leg extensor muscle strength, which remained about 10% greater in the exercise groups compared with the reference group (D(-)Ex(-)). There were no between-group differences in the rate of all falls, but medically attended injurious falls reduced in D+ Ex-and D(-)Ex(+) groups compared with D(-)Ex(-). However, all former treatment groups had less medically attended injured fallers, HRs (95% CI) being 0.62 (0.39-1.00) for D+ Ex-, 0.46 (0.28-0.76) for D(-)Ex(+), and 0.55 (0.34-0.88) for D(+)Ex(+), compared with D(-)Ex(-). Exercise-induced benefits in physical functioning partly remained 2 years after cessation of supervised training. Although there was no difference in the rate of all falls, former exercise groups continued to have lower rate of medically attended injured fallers compared with referents even 2 years after the intervention."
According to the news editors, the research concluded: "Vitamin D without exercise was associated with less injurious falls with no difference in physical functioning."
For more information on this research see: A 2-Year Follow-Up After a 2-Year RCT with Vitamin D and Exercise: Effects on Falls, Injurious Falls and Physical Functioning Among Older Women. Journals of Gerontology Series A-Biological Sciences and Medical Sciences, 2017;72(9):1239-1245. Journals of Gerontology Series A-Biological Sciences and Medical Sciences can be contacted at: Oxford Univ Press Inc, Journals Dept, 2001 Evans Rd, Cary, NC 27513, USA (see also Aging Research - Geriatrics and Gerontology).
The news editors report that additional information may be obtained by contacting K. Uusi-Rasi, UKK Inst Hlth Promot Res, FI-33501 Tampere, Finland. Additional authors for this research include R. Patil, S. Karinkanta, P. Kannus, K. Tokola, C. Lamberg-Allardt and H. Sievanen.
Keywords for this news article include: Tampere, Finland, Europe, Geriatrics and Gerontology, Aging Research, UKK Institute for Health Promotion Research.
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