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Studies from A. Castello et al in the Area of Breast Cancer Described (Adherence to the Western, Prudent and Mediterranean dietary patterns and...

Cancer Weekly


Studies from A. Castello et al in the Area of Breast Cancer Described (Adherence to the Western, Prudent and Mediterranean dietary patterns and breast cancer risk: MCC-Spain study)

By a News Reporter-Staff News Editor at Cancer Weekly -- Current study results on Oncology - Breast Cancer have been published. According to news reporting originating from Madrid, Spain, by NewsRx correspondents, research stated, "To externally validate the previously identified effect on breast cancer risk of the Western, Prudent and Mediterranean dietary patterns. MCC-Spain is a multicase-control study that collected epidemiological information on 1181 incident cases of female breast cancer and 1682 healthy controls from 10 Spanish provinces."

Our news editors obtained a quote from the research, "Three dietary patterns derived in another Spanish case-control study were analysed in the MCC-Spain study. These patterns were termed Western (high intakes of fatty and sugary products and red and processed meat), Prudent (high intakes of low-fat dairy products, vegetables, fruits, whole grains and juices) and Mediterranean (high intake of fish, vegetables, legumes, boiled potatoes, fruits, olives, and vegetable oil, and a low intake of juices). Their association with breast cancer was assessed using logistic regression models with random province-specific intercepts considering an interaction with menopausal status. Risk according to tumour subtypes based on oestrogen (ER), progesterone (PR) and human epidermal growth factor 2 (HER2) receptors (ER +/PR + HER2; HER2+; ER- /PR- & HER2-) -was evaluated with multinomial regression models. Breast cancer and histological subtype. Our results confirm most of the associations found in the previous case-control study. A high adherence to the Western dietary pattern seems to increase breast cancer risk in both premenopausal women (OR4th vs 1st quartile (95% CI):1.68 (1.02;2.79); ORISD-increase (95% CI):1.19 (1.02;1.40)) and postmenopausal women (OR4th vs 1st quartile(95% CI):1.48(1.07;2.05); ORISD-increase(95% CO: 1.14 (1.01;1.29)). While high adherence to the Prudent pattern did not show any effect on breast cancer, the Mediterranean dietary pattern seemed to be protective, but only among postmenopausal women (OR4th vs 1st quartile (95% CI): 0.72 (95% CI 0.53;0.98); p-int = 0.075). There were no significant differences by tumour subtype."

According to the news editors, the research concluded: "Dietary recommendations based on a departure from the Western dietary pattern in favour of the Mediterranean diet could reduce breast cancer risk in the general population."

For more information on this research see: Adherence to the Western, Prudent and Mediterranean dietary patterns and breast cancer risk: MCC-Spain study. Maturitas, 2017;103():8-15. Maturitas can be contacted at: Elsevier Ireland Ltd, Elsevier House, Brookvale Plaza, East Park Shannon, Co, Clare, 00000, Ireland. (Elsevier -; Maturitas -

The news editors report that additional information may be obtained by contacting A. Castello, IIS Puerta Hierro IDIPHIM, Oncol & Hematol Area, Canc Epidemiol Res Grp, Madrid 28222, Spain. Additional authors for this research include E. Boldo, B. Perez-Gomez, V. Lope, J.M. Altzibar, V. Martin, G. Castano-Vinyals, M. Guevara, T. Dierssen-Sotos, A. Tardon, V. Moreno, M. Puig-Vives, C. Llorens-Ivorra, J. Alguacil, I. Gomez-Acebo, J. Castilla and Gracia-Lavedan (see also Oncology - Breast Cancer).

Keywords for this news article include: Madrid, Spain, Europe, Breast Ductal Carcinoma, Oncology, Epidemiology, Risk and Prevention, Women's Health, Breast Cancer, Cancer Risk.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2017, NewsRx LLC

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