Life Extension Update

Vitamins, Health Supplements, Anti Aging Supplements: Life Extension Update

Life Extension Update is a free email newsletter sent to subscribers twice weekly. Our premier e-mail update features information and breaking news about longevity, vitamins, nutritional health supplements, anti aging supplements, and other life extension topics to assist you in living longer and healthier.

Newsletters will be posted in this archive two weeks after they are sent to subscribers. Subscribe today to stay informed of the latest in health and nutrition news as it happens!

Life Extension Update

Omega-3 improves treatment response and quality of life in advanced pancreatic cancer patients

Life Extension Update

Tuesday, August 4, 2015. On July 28, 2015, the Journal of Parenteral and Enteral Nutrition reported the outcome of a study of advanced pancreatic cancer patients which found improved response to chemotherapy and better quality of life with the addition of omega-3 fatty acids.

The study included 50 men and women with locally advanced or metastatic pancreatic adenocarcinoma who had not received prior chemotherapy. Participants received a standard dose of the drug gemcitabine, immediately followed by an intravenous infusion of up to 100 grams of an omega-3 rich lipid emulsion weekly for three weeks followed by one rest week, which was continued for up to six cycles. Computed tomography (CT) scans of the chest, abdomen and pelvis were conducted at the beginning of the study and at every two cycles thereafter. Quality of life and other factors were assessed by patient questionnaires completed weekly.

Stabilized disease or partial treatment response occurred in 30 of the 35 subjects who completed the study. Progression free survival was longer than that which has been observed in association with gemcitabine treatment alone. Among the 36 patients who completed at least four treatments, more than half of the subjects experienced an improvement in pain and disease symptoms. A sustained increase in global health of greater than 10% was observed in 47.2% of the participants, which is a significantly greater percentage of subjects than that which has been associated with gemcitabine in another study.

"This is the first report of the combination of a chemotherapeutic agent and intravenous omega-3 rich lipid emulsion in any cancer setting," announce authors Ali Arshad and colleagues at England's University Hospitals of Leicester. "There was evidence of activity in terms of response and disease stabilization rates and reduction in liver metastasis volume as well as Quality of Life scores in this group of patients . . . Rates of disease control are encouraging compared to existing data."

"We would suggest a phase III randomized controlled trial to assess the independent contribution of omega-3 lipids to this effect," they conclude.


View This Issue

Recent NewsLetter Articles

Back issues of Life Extension Update are archived approximately two weeks following their publication. To make sure you have not missed out on exciting news concerning health and nutrition, vitamins, and the health supplements you rely on for optimal health, check here for a list of issues of Life Extension Update.

Life Extension Update Archive