Highest Quality Supplements Since 1980

Read (18) Reviews
Write a Review

Mega Benfotiamine

Supports Healthy Blood Sugar Metabolism

250 mg, 120 vegetarian capsules
Item# 00925

Retail Price: $30.00

Your Price:

Your favorite Life Extension® products can be delivered to you automatically. Just look for the “AutoShip” button. Select AutoShip, and choose your preferred ship-out date. It's that easy!


  • Mega Benfotiamine
  • 250 mg, 120 vegetarian capsules
  • Item Catalog Number: 00925

Benfotiamine, a fat-soluble form of vitamin B1 (thiamine), supports healthy blood sugar metabolism and helps protect the body’s tissues against advanced glycation end products and oxidative stress.66 For example, the enzyme transketolase is critical to blood sugar metabolism. Like many enzymes, transketolase requires a co-factor. In this case, it needs assistance from thiamine. Unfortunately, thiamine is water-soluble, which makes it less available to the interior of the cell. Benfotiamine is fat-soluble and can easily penetrate into the inside of cells. It is also more bioavailable than the water-soluble thiamine.

In a landmark study, benfotiamine effectively increased transketolase activity in cell cultures by an astounding 300%, compared to a mere 20% for thiamine. This robust activation was sufficient to block three of the four major metabolic pathways leading to blood vessel damage.66 Benfotiamine also blocks the activation of the transcription factor known as nuclear factor-kappa B (NF-kB), which is implicated in numerous inflammatory conditions.66 

Overall, benfotiamine can activate glucose metabolism and promote healthy blood glucose levels in those already within normal range. Benfotiamine also helps maintain healthy endothelial function67-73 and supports the health of the nerves, kidneys, eyes, blood vessels, and heart.



Supplement Facts

Serving Size 1 vegetarian capsule

Amount Per Serving

Thiamine (vitamin B1) (as thiamine HCl)

10 mg


250 mg

Other ingredients: microcrystalline cellulose, vegetable cellulose (capsule), dicalcium phosphate, rice flour, vegetable stearate, silica.


Dosage and Use
  • Take one (1) to four (4) capsule(s) daily with or without food, or as recommended by a healthcare practitioner.


Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of Life Extension. We do not verify or endorse any claims made in these reviews. Please read the full product reviews disclaimer.