Highest Quality Supplements Since 1980

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  • Gentle-C™
  • 1000 mg 100 tablets
  • Item Catalog Number: 16787

Vitamin C, or ascorbic acid, is a white, crystalline, water-soluble substance found in citrus fruits. As an antioxidant, vitamin C scavenges free radicals in the body and protects tissues from oxidative stress.1-8 Vitamin C also promotes the absorption of iron, while preventing its oxidation.9,10 Vitamin C is a vital cofactor to the formation of collagen, the connective tissue that supports arterial walls, skin, bones, and teeth.4-6 A major immune-supporting activity of vitamin C is boosting glutathione levels in human lymphocytes,38 cells that make up about 25% of all white cells in the blood.

More vitamin C is contained in the adrenal glands than any other organ in the body and is required at higher levels during times of stress.11-14 Physical stresses on the body such as ingestion of heavy metals,15-20 cigarette smoking,21-24 immune impairment,25-31 extreme temperatures,31-36 and chronic use of certain medications such as aspirin also signal the need for increased intake of vitamin C.37

This TwinLab® product contains a unique calcium-bound ascorbate complex. This is a non-acidic form of vitamin C that may have a longer serum half-life than regular ascorbic acid. The product also contains a citrus bioflavonoid complex.

1. Biochim Biophys Acta. 2012 Dec;1826(2):443-57.
2. Redox Rep. 2010;15(1):11-9.
3. Adv Nutr. 2011 Mar;2(2):78-88.
4. Altern Med Rev. 2003 Nov;8(4):359-77.
5. J Invest Dermatol. 2002 Apr;118(4):565-72.
6. Radiat Environ Biophys. 2007 Mar;46(1):61-8.
7. Free Radic Biol Med. 2007 Sep 1;43(5):853-9.
8. PLoS Negl Trop Dis. 2012;6(7):e1729.
9. Br J Nutr. 2003 Dec;90(6):1081-5.
10. Am J Clin Nutr. 2006 Oct;84(4):830-4.
11. In Vivo. 1994 Nov-Dec;8(6):1079-85.
12. Ann Nutr Metab. 1990;34(2):85-92.
13. Psychopharmacology (Berl). 2002 Jan;159(3):319-24
14. Am J Clin Nutr. 2007 Jul;86(1):145-9.
15. Genet Test Mol Biomarkers. 2012 Sep;16(9):1001-6.
16. Environ Toxicol Pharmacol. 2011 Jan;31(1):137-42.
17. Acta Biochim Biophys Sin (Shanghai). 2012 Apr;44(4):330-8.
18.Nig Q J Hosp Med. 2012 Apr-Jun;22(2):85-90.
19. Toxicology. 2005 Jul 1;211(1-2):26-35. 
20. Chem Biol Interact. 2001 Jul 31;137(1):75-88.
21. Environ Health Perspect. 2000 Feb;108(2):105-8.
22. Am J Ther. 2007 Mar-Apr;14(2):189-93.
23. Am J Clin Nutr. 2000 Feb;71(2):530-6.
24. Toxicology. 2002 Nov 15;180(2):121-37.
25. J Am Coll Cardiol. 2003 Nov 5;42(9):1656-62.
26. J Pediatr Gastroenterol Nutr. 2003 Jul;37(1):53-62.
27. Cancer Sci. 2003 Apr;94(4):378-82.
28. Adv Ther. 2002 May-Jun;19(3):151-9.
29. Br J Dermatol. 1980 Jan;102(1):49-56.
30. Respir Med. 2007 Aug;101(8):1770-8.
31. Acta Obstet Gynecol Scand. 2007;86(7):783-7.
32. J Int Med Res. 2012;40(1):28-42.
33. Vopr Pitan. 1978 Jan-Feb;(1):44-8.
34. J Am Coll Nutr. 1990 Apr;9(2):150-4.
35. Jpn J Physiol. 1999 Apr;49(2):159-67.
36. Indian J Med Res. 2002 Jul;116:29-34.
37. Med Sci Monit. 2001 Jul-Aug;7(4):592-9.


Supplement Facts

Serving Size 1 tablet

Servings Per Container 100

Amount Per Serving

Ester-C calcium ascorbate

1100 mg



Vitamin C

1000 mg

Elemental calcium

100 mg

Citrus bioflavonoid complex

200 mg

Other ingredients: cellulose, croscarmelose sodium, vegetable based stearic acid, dicalcium phosphate, triacetin, magnesium silicate, caruba powder, purified water.
100% vegetarian tablets. Free of sugars, salt (sodium), wheat, starch, yeast, dairy, artificial colors, flavors and preservatives.

Dosage and Use
  • One or more tablets daily with a meal is suggested, or as directed by a healthcare practitioner.


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