What's Hot in Nutrition, Dietary Supplements, Health and Wellness Today
What's Hot features original summaries of the latest peer-reviewed journal articles published in the fields of longevity, dietary supplements, health and wellness, and nutrition. Access the latest news concerning nutritional supplements and vitamins online at What's Hot each Monday, Wednesday and Friday. Articles are archived by month and year of publication for easy retrieval. What's Hot reports exciting findings on everything from the vitamins and supplements you and your family use on a daily basis to advanced high tech breakthroughs in the field of gerontology.
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Nicotinamide riboside shows promise in regenerative medicine
May 2 2016. An article published online on April 28, 2016 in the journal Science reveals more positive findings for nicotinamide riboside, a natural compound that is a precursor of nicotinamide adenine dinucleotide (NAD+) found in all living cells.
A team from École Polytechnique Fédérale de Lausanne in Switzerland, along with researchers from Zurich, Canada and Brazil, found that treatment with nicotinamide riboside rejuvenated muscle stem cells in aged mice and prevented muscle stem cell senescence in a mouse model of muscular dystrophy. They also determined that the compound delayed the senescence of neural and melanocyte stem cells in addition to increasing life span in mice.
The team identified the molecular chain that regulates the function of mitochondria (the cells' energy-producing organelles) and how mitochondria change during aging. "We were able to show for the first time that their ability to function properly was important for stem cells," announced lead researcher Johan Auwerx.
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