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October 1999

By Karin Granstrom Jordan, M.D.

Osteoarthritis & Rheumatoid Arthritis        


Bates CJ: Proline and hydroxyproline excretion and vitamin C status in elderly human subjects. Clin Sci Mol Med (1977) 52: 535-43.

Belluzzi A et al.: Effect of an enteric-coated fish-oil preparation on relapses in Crohn's disease. NEJM (1996) 334: 1557-1560.

Bertolini DR et al.: Stimulation of bone resorption and inhibition of bone formation in vitro by human tumor necrosis factor. Nature (1986) 319: 516-18.

Birkedal-Hansen H et al.: Matrix metalloproteinases: A review. Crit Rev Oral Biol Med (1993) 4: 197-250.

Bondeson J et al.: Defining therapeutic targets by using adenovirus: Blocking NK-kB inhibits both inflammatory and destructive mechanisms in rheumatoid synovium but spares anti-inflammatory mediators. Proc Natl Acad Sci USA (1999) 96: 5668-5673.

Bourgeois P et al.: Efficacy and tolerability of chondroitin sulfate 1200mg/day vs placebo. Osteoarth Cartil (1998) 6, Suppl. A: 25-30.

Brooks PM et al.: NSAID and osteoarthritis - help or hindrance. J Rheumatol (1982) 9: 3-5.

Bucsi L et al.: Efficacy and tolerability of oral chondroitin sulfate as a slow-acting drug for osteoarthritis (SYSADOA) in the treatment of knee osteoarthritis. Osteoarth Cartil (1998) 6, Suppl. A: 31-36.

Caugey GE et al.: The effect on human tumor necrosis factor-a and interleukin-1b production of diets enriched in n-3 fatty acids from vegetable oil or fish oil. Am J Clin Nutr (1996) 63: 116-22.

Chrubasik S et al.: Evidence for antirheumatic effectiveness of Herba Urticae dioicae in acute arthritis: a pilot study. Phytomedicine (1997) 4: 105-108.

Engstrom K et al.: Effect of Low-dose aspirin in combination with Stable Fish Oil on Eicosanoids. EPA and Eicosanoids. Prost Leukotr Ess Fat Acid (1997) 57: 229.

Feldmann M et al.: Anti-tumor necrosis factor-a therapy of rheumatoid arthritis. Adv Immunol (1997) 84: 283-350.

Feldmann M et al.: Role of cytokines in rheumatoid arthritis. Annu Rev Immunol (1996) 14: 397-440.

Flynn DL et al.: Inhibition of human neutrophil 5-lipoxygenase activity by gingerdione, shogaol, capsaicin and related pungent compounds. Prost Leukotr Med (1986) 24: 195-198.

Hardingham T: Chondroitin sulfate and joint disease. Osteoarth Cartil (1998) 6, Suppl. A: 3-5.

Hill PA et al.: The effects of selective inhibitors of matrix metalloproteinases on bone resorption and the identification of MMPs and TIMP-1 in isolated osteoclasts. J Cell Sci (1994) 107: 3055-3064.

James MJ et al.: Dietary n-3 fatty acids and therapy for rheumatoid arthritis. Semin Arthritis Rheum (1997) 27: 85-97.

Kiuchi F et al.: Inhibition of prostaglandin and leucotriene biosynthesis by gingerols and diarylheptanoids. Chem Pharm Bull (1992) 40: 387-391.

Jue DM et al.: Nuclear factor kb (NF-kb) pathway as a therapeutic target in rheumatoid arthritis. J Kor Med Sci (1999) 14: 231-238.

Kremer JM et al.: Clinical studies of n-3 fatty acids supplementation in patients with rheumatoid arthritis. Rheum Dis Clinics (1992) 17: 391-402.

Kremer JM et al.: Effects of manipulation of dietary fatty acids on clinical manifestations of rheumatoid arthritis. Lancet (1985) 1(8422): 184-187.

Kremer JM et al.: Fish-oil fatty acid supplementation in active rheumatoid arthritis: a double-blinded, controlled crossover study. Ann Int Med (1987) 106: 497-503.

Needleman P et al.: Triene prostaglandins: prostacyclin and thromboxane biosynthesis and unique biological properties. Proc Natl Acad Sci USA (1979) 76:944-948.

Newman NM et al.: Acetabular bone destruc tion related to non-steroidal anti-inflammatory drugs. Lancet (1985) 2(8445): 11-14.

Obertreis B et al: Ex-vivo in-vitro inhibition of lipopolysaccharide stimulated tumor necrosis factor-a and Interleukin-1b secretion in man whole blood by extractum Urticae dioicae foliorum. Arzneim-Forsch/Drug Res (1996) 46: 389-394.

Paulus HE et al.: Analysis of improvement in individual rheumatoid arthritis patients treated with disease-modifying antirheumatic drugs, based on the findings in patients treated with placebo. Arthr Rheum (1990) 33: 477-484.

Plows D et al.: the role of tumor necrosis factor (TNF) in arthritis: studies in transgenic mice. Rheumatol Eur (1995) Suppl 2: 51-4.

Prashker MJ et al: the total cost of drug therapy for rheumatoid arthritis: a model based on costs of drug, monitoring and xicity. Arthr Rheum (1995) 38: 318-25.

Qiu GX et al.: Efficacy and safety of glucosamine sulfate versus ibuprofen in patients with knee osteoarthritis. Arzneim-Forsch/Drug Res (1998) 48: 469-474.

Riehemann K et al.: Plant extracts from stinging nettle (Urtica dioica), an antirheumatic remedy, inhibit the proinflammatory transcription factor NF-kb. FEBS Lett (1999) 442: 89-94.

Robinson DR et al.: Lipid mediators of inflammatory and immune reactions. J Parent Ent Nutr (1988) 12, Suppl. S: S37-S42.

Ronningen H et al: Indomethacin treatment in osteoarthritis of the hip joint. Acta Orthop Scand (1979) 50: 169-74.

Saklatvala J: Tumor necrosis factor-a stimulates resorption and inhibits synthesis of proteoglycan in cartilage. Nature (1986) 322: 547-49.

Sharma JN et al.: Effects of eugenol and ginger oil on adjuvant arthritis and the kallikreins in rats. Asia Pac J Pharmacol (1997) 12: 9-14.

Sharma JN et al.: Suppressive effects of eugenol and ginger oil on arthritic rats. Pharmacology (1994) 49: 314-318.

Shield MJ: Anti-inflammatory drugs and their effect on cartilage synthesis and renal function. Eur J Rheum Inflam (1993) 13: 7-16.

Skoldstam L et al.: Effects of six months of fish oil supplementation in stable rheumatoid arthritis: A double-blind, controlled udy. Scand J Rheum (1992) 21: 178-185.

Solomon L: Drug induced arthropathy and necrosis of the femoral head. J Bone Joint Surg (1973) 55B: 246-51.

Sperling RI et al.: Effects of dietary supplementation with marine fish oil on leucocyte lipid mediator generation and function in rheumatoid arthritis. Arthr Rheum (1987) 30: 988-997.

Srivastava KC et al: Ginger (Zingiber-officinale) and rheumatic disorders. Med Hypoth (1989) 29: 25-8.

Srivastava KC: Ginger (Zingiber-officinale) in rheumatism and muscular skeletal disorders. Med Hypoth (1992) 39: 342-348.

Uebelhart D et al.: Effects of oral chondroitin sulfate on the progression of knee osteoarthritis: a pilot study. Osteoarth Cartil ( 98) 6, Supplement A: 39-46.

Verbruggen G et al.: Chondroitin sulphate S/DMOAD (structure/disease modifying anti-osteoarthritis drug) in the treatment of finger joint OA. Osteoarth Cartil (1998) 6, Suppl. A: 37-38.