Study Findings from A. Ishigami et al Provide New Insights into Vitamins (Protective effect of pre- and post-vitamin C treatments on UVB-irradiation-induced skin damage)
Genomics & Genetics Weekly
Our news editors obtained a quote from the research, "Therefore, we investigated the effect of AA on UVB-induced skin damage using reconstituted human epidermis. The reconstituted human epidermal surface was treated with 100 and 500 mM AA and cultured for 3 h before (pre-AA treatment) or after (post-AA treatment) 120 mJ/cm(2) UVB irradiation. Preand post-AA treatments of the epidermal surface suppressed UVB-induced cell death, apoptosis, DNA damage, reactive oxygen species (ROS) production, and the inflammatory response by downregulating tumour necrosis factor-alpha (TNF-alpha) expression and release. Moreover, the pre-AA treatment was more effective at preventing UVB-induced skin damage than the post-AA treatment."
According to the news editors, the research concluded: "In summary, pre-and post-AA treatments of the epidermis prevent UVB-induced damage."
For more information on this research see: Protective effect of pre- and post-vitamin C treatments on UVB-irradiation-induced skin damage. Scientific Reports, 2018;8():557-568. Scientific Reports can be contacted at:
The news editors report that additional information may be obtained by contacting A. Ishigami, Tokyo Metropolitan Inst Gerontol, Mol Regulat Aging,
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