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Research Conducted at Griffith University Has Updated Our Knowledge about Dementia (Increased All-Cause Mortality by Antipsychotic Drugs: Updated Review and Meta-Analysis in Dementia and General Mental Health Care)

Mental Health Weekly Digest


By a News Reporter-Staff News Editor at Mental Health Weekly Digest -- Current study results on Neurodegenerative Diseases and Conditions - Dementia have been published. According to news reporting from Gold Coast, Australia, by NewsRx journalists, research stated, "It is almost ten years since the Banerjee 2009 report established that inappropriate prescribing of antipsychotics in the elderly was occurring in the UK and such patients had an 85% increased risk of adverse events and greater mortality. This report was a critical analysis addressing the outcomes of treatment practices for dementia in UK patients and globally, aimed at reducing prescribing of antipsychotic drugs for dementia."

The news correspondents obtained a quote from the research from Griffith University, "Since 2009, many significant studies worldwide (including several more recent large retrospective studies) provide more extensive longitudinal data for the adverse impacts of antipsychotic drugs in dementia. We have used the data in these studies including from over 380,000 dementia patients, with 85,069 prescribed antipsychotic agents as well as from 359,235 non-dementia antipsychotic drug users to provide an up-dated meta-analysis. This is the first meta-analysis to include evidence from general mental health studies showing that antipsychotic drugs precipitate excessive mortality across the spectrum."

According to the news reporters, the research concluded: "Prescribing of antipsychotic drugs for dementia or for other mental health care should be avoided and alternative means sought for handling behavioral disorders of such patients."

For more information on this research see: Increased All-Cause Mortality by Antipsychotic Drugs: Updated Review and Meta-Analysis in Dementia and General Mental Health Care. Journal of Alzheimer's Disease Reports, 2018;2(1):1-26 (see also Neurodegenerative Diseases and Conditions - Dementia).

Our news journalists report that additional information may be obtained by contacting S.J. Ralph, School of Medical Science, Griffith University, Gold Coast, Southport, QLD, Australia.

The direct object identifier (DOI) for that additional information is: https://doi.org/10.3233/ADR-170042. This DOI is a link to an online electronic document that is either free or for purchase, and can be your direct source for a journal article and its citation.

(Our reports deliver fact-based news of research and discoveries from around the world.)

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