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Data on Cancer Detailed by Researchers at Southwest Medical University (Repurposing Vitamin D for Treatment of Human Malignancies Via Targeting Tumor Microenvironment)

Stem Cell Daily

04-24-19

2019 APR 23 (NewsRx) -- By a News Reporter-Staff News Editor at Stem Cell Daily -- Investigators discuss new findings in Cancer. According to news reporting out of Luzhou, People’s Republic of China, by NewsRx editors, research stated, “Tumor cells along with a small proportion of cancer stem cells exist in a stromal microenvironment consisting of vasculature, cancer-associated fibroblasts, immune cells and extracellular components. Recent epidemiological and clinical studies strongly support that vitamin D supplementation is associated with reduced cancer risk and favorable prognosis.”

Funders for this research include National Natural Science Foundation of China, Science and Technology Planning Project of Luzhou, Sichuan Province, China.

Our news journalists obtained a quote from the research from Southwest Medical University, “Experimental results suggest that vitamin D not only suppresses cancer cells, but also regulates tumor microenvironment to facilitate tumor repression. In this review, we have outlined the current knowledge on epidemiological studies and clinical trials of vitamin D. Notably, we summarized and discussed the anticancer action of vitamin D in cancer cells, cancer stem cells and stroma cells in tumor microenvironment, providing a better understanding of the role of vitamin D in cancer.”

According to the news editors, the research concluded: “We presently re-propose vitamin D to be a novel and economical anticancer agent.”

For more information on this research see: Repurposing Vitamin D for Treatment of Human Malignancies Via Targeting Tumor Microenvironment. Acta Pharmaceutica Sinica B, 2019;9(2):203-219. Acta Pharmaceutica Sinica B can be contacted at: Inst Materia Medica, Chinese Acad Medical Sciences, C, O Editorial Board Of Acta Pharmaceutica Sinica, 1 Xiannongtan St, Beijing, 100050, Peoples R China. (Elsevier - www.elsevier.com; Acta Pharmaceutica Sinica B - http://www.journals.elsevier.com/acta-pharmaceutica-sinica-b/)

Our news journalists report that additional information may be obtained by contacting J. Shen, Southwest Medical University, Laboratory for Molecular Pharmacology, Dept. of Pharmacology, School of Pharmacy, Luzhou 646000, People’s Republic of China. Additional authors for this research include X. Wu, Y.S. Zhao, Z.G. Xiao, L. Zhang, H.Y. Zhang, X.B. Li, W.P. Li, C.H. Cho, M.X. Li, W. Hu, L. Lu, Y.J. Zhou and S.P. Wang.

The direct object identifier (DOI) for that additional information is: https://doi.org/10.1016/j.apsb.2018.09.002. This DOI is a link to an online electronic document that is either free or for purchase, and can be your direct source for a journal article and its citation.

(Our reports deliver fact-based news of research and discoveries from around the world.)

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