Reports from Kyoto Women’s University Add New Data to Findings in Nutritional Science and Vitaminology (Relationship Between Homocysteine, Folate, Vitamin B-12 and Physical Performance In the Institutionalized Elderly)
NewsRx Cardiovascular Daily
2019 APR 23 (NewsRx) -- By a News Reporter-Staff News Editor at NewsRx Cardiovascular Daily -- A new study on Diet and Nutrition - Nutritional Science and Vitaminology is now available. According to news reporting originating from Kyoto, Japan, by NewsRx correspondents, research stated, “Hyperhomocysteinemia causes various diseases including cardiovascular disease, osteoporotic fracture and dementia. Although there have been reports that hyperhomocysteinemia decreases physical performance, findings are inconsistent on the association of homocysteine, folate, vitamin B-12 and physical performance.”
Financial support for this research came from JSPS KAKENHI.
Our news editors obtained a quote from the research from Kyoto Women’s University, “Considering that lower physical performance increases the risk of fall and fracture in the elderly, the effect of nutritional status on physical function must be clarified. This is a cross-sectional study conducted from April 2015 to November 2016. Eighty-six residents and users in five care facilities were evaluated for their blood homocysteine, folate and vitamin B-12 concentrations and indices for physical performance; lower limb muscle strength, handgrip strength and gait speed. Analyses of physical performance were done in women only, considering the high proportion of women in the study population and the muscular gender difference. In the third tertile of plasma homocysteine concentration, handgrip strength was significantly lower than in the first tertile (p=0.027). In the first tertile of serum folate concentration, handgrip strength was significantly lower than in the third tertile (p=0.002). Although not statistically significant, lower limb muscle strength in the third tertile of folate was higher than in the first (p=0.061) and second (p=0.057) tertile. In the multiple regression analysis, however, only serum folate concentration was a significant contributor except for age. In subjects with their serum folate and vitamin B-12 concentrations both exceeding the median, lower limb muscle strength was higher.”
According to the news editors, the research concluded: “Low serum folate concentration is a risk factor for lower physical performance independent of homocysteine in elderly women.”
For more information on this research see: Relationship Between Homocysteine, Folate, Vitamin B-12 and Physical Performance In the Institutionalized Elderly. Journal of Nutritional Science and Vitaminology, 2019;65(1):1-7. Journal of Nutritional Science and Vitaminology can be contacted at: Center Academic Publ Japan, 2-4-16 Yayoi, Bunkyo-Ku, Tokyo, 113-0032, Japan.
The news editors report that additional information may be obtained by contacting M. Ao, Kyoto Women’s University, Dept. of Food and Nutrition, Kyoto 6058501, Japan. Additional authors for this research include N. Inuiya, T. Miyawaki, K. Tanaka, J. Ohta, S. Knrose, H. Takaoka, Y. Abe, N. Niki, S. Inoue and S. Tanaka.
The direct object identifier (DOI) for that additional information is: https://doi.org/10.3177/jnsv.65.1. This DOI is a link to an online electronic document that is either free or for purchase, and can be your direct source for a journal article and its citation.
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