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Research from Niigata University Faculty of Medicine Reveals New Findings on Type 2 Diabetes

Angiogenesis Daily


2019 JUN 19 (NewsRx) -- By a News Reporter-Staff News Editor at Angiogenesis Daily -- Current study results on Nutritional and Metabolic Diseases and Conditions - Type 2 Diabetes have been published. According to news reporting originating from Niigata, Japan, by NewsRx correspondents, research stated, “Although vitamin B6 has been suspected to prevent the progression of diabetic retinopathy, evidence of this in patients with type 2 diabetes based on longitudinal studies is sparse. This study investigated the relationship between vitamin B6 intake and the incidence of diabetic retinopathy in Japanese patients with type 2 diabetes.”

Financial supporters for this research include Japan Society for the Promotion of Science, Ministry of Health, Labor and Welfare, Japan.

Our news editors obtained a quote from the research from the Niigata University Faculty of Medicine, “The study was part of an examination of a nationwide cohort of patients with type 2 diabetes aged 40-70 years with HbA1c 48 mmol/mol. After excluding nonresponders to a dietary survey using the Food Frequency Questionnaire based on food groups, 978 patients were analyzed. Primary outcome was the 8-year risk of a diabetic retinopathy event, and Cox regression analyses estimated hazard ratios (HRs) for retinopathy according to vitamin B6 intake adjusted for age, gender, body mass index, HbA1c, smoking, energy intake, and other confounders. Mean vitamin B6 intake in quartiles ranged from 1.1 to 1.6 mg/day, and half of the participants had vitamin B6 intake below the recommended daily dietary allowance according to dietary reference intakes in Japanese adults (men 1.4 mg/day; women 1.2 mg/day). After adjusting for confounders, HRs for diabetic retinopathy in the 2nd, 3rd, and 4th quartile groups of vitamin B6 intake compared with the 1st quartile group were 1.17 (95% confidence interval 0.81-1.69, p=0.403), 0.88 (0.58-1.34, p=0.550), and 0.50 (0.30-0.85, p=0.010), respectively.”

According to the news editors, the research concluded: “Findings suggested that high vitamin B6 intake was associated with a lower incidence of diabetic retinopathy in Japanese with type 2 diabetes.”

For more information on this research see: Vitamin B6 intake and incidence of diabetic retinopathy in Japanese patients with type 2 diabetes: analysis of data from the Japan Diabetes Complications Study (JDCS). European Journal of Nutrition, 2019;():. (Springer -; European Journal of Nutrition -

The news editors report that additional information may be obtained by contacting H. Sone, Dept. of Hematology, Endocrinology and Metabolism, Niigata University Faculty of Medicine, 1-757 Asahimachi-dori, Chuoh-ku, Niigata, 951-8510, Japan. Additional authors for this research include R. Aida, C. Kamada, K. Fujihara, S. Tanaka, S. Tanaka, A. Araki, Y. Yoshimura, T. Moriya, Y. Akanuma and H. Sone.

The direct object identifier (DOI) for that additional information is: This DOI is a link to an online electronic document that is either free or for purchase, and can be your direct source for a journal article and its citation.

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