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New Findings Reported from Cerrahpasa Faculty of Medicine Describe Advances in Caloric Restriction (Caloric restriction and redox homeostasis in various regions of aging male rat brain: Is caloric restriction still worth trying even after ...)

Pain & Central Nervous System Daily News

08-13-19

2019 AUG 12 (NewsRx) -- By a News Reporter-Staff News Editor at Pain & Central Nervous System Daily News -- Data detailed on Diet and Nutrition - Caloric Restriction have been presented. According to news reporting originating in Istanbul, Turkey, by NewsRx journalists, research stated, “Despite recent studies have shown that caloric restriction (CR) could improve some functional loss associated with brain aging, the biochemical effects of CR on brain aging are still not well understood on a quantifiable biochemical basis, including whether CR could be protective when started around middle adulthood, when age-related neurodegenerative diseases are thought to set in.”

Financial support for this research came from Istanbul Universitesi.

The news reporters obtained a quote from the research from the Cerrahpasa Faculty of Medicine, “Therefore, in the light of more than ever aging societies and increasing neurodegenerative diseases, we aimed to test the biochemical effects of CR on redox homeostasis in different parts of male Sprague-Dawley rat brain by using the biomarkers we consistently validated in our previous work (TOS, PCO, AOPP, AGEs, sRAGE, P-SH, LHPs, 4-HNE, TAS, Cu, Zn-SOD). Our results indicate that oxidative stress biomarkers are lower in CR group, implying a more favorable redox status that has been previously shown to be correlated with better neural function.”

According to the news reporters, the research concluded: “We report that the beneficial effects of caloric restriction (CR) on various brain tissues result in significant improvements in biochemical markers, even though CR is not started in early adulthood. Hence, our select age group provides a sound redox status-related neurochemical understanding for many recent CR studies, where a functional loss was detected at this age.”

For more information on this research see: Caloric restriction and redox homeostasis in various regions of aging male rat brain: Is caloric restriction still worth trying even after early-adulthood?: Redox homeostasis and caloric restriction in brain. Journal of Food Biochemistry, 2018;43(3):e12740. Journal of Food Biochemistry can be contacted at: Blackwell Publishing Inc, 350 Main St, Malden, MA 02148, USA. (Wiley-Blackwell - http://www.wiley.com/; Journal of Food Biochemistry - http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1745-4514)

Our news correspondents report that additional information may be obtained by contacting K. Yanar, Cerrahpasa Faculty of Medicine, Dept. of Medical Biochemistry, Istanbul University-Cerrahpasa, Istanbul, Turkey. Additional authors for this research include B. Simsek, N. Cayli, H. Ovul Bozkir, M. Mengi, A. Belce, S. Aydin and U. Cakatay.

The direct object identifier (DOI) for that additional information is: https://doi.org/10.1111/jfbc.12740. This DOI is a link to an online electronic document that is either free or for purchase, and can be your direct source for a journal article and its citation.

The publisher of the Journal of Food Biochemistry can be contacted at: Blackwell Publishing Inc, 350 Main St, Malden, MA 02148, USA.

(Our reports deliver fact-based news of research and discoveries from around the world.)

Articles featured in Life Extension Daily News are derived from a variety of news sources and are provided as a service by Life Extension. These articles, while of potential interest to readers of Life Extension Daily News, do not necessarily represent the opinions nor constitute the advice of Life Extension.

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