Reports Summarize Morphological Science Study Results from Kyung Hee University (The natural plant flavonoid apigenin is a strong antioxidant that effectively delays peripheral neurodegenerative processes)
South Korea Daily Report
2019 AUG 13 (NewsRx) -- By a News Reporter-Staff News Editor at South Korea Daily Report -- Current study results on Life Science Research - Morphological Science have been published. According to news reporting out of Seoul, South Korea, by NewsRx editors, research stated, “Oxidative stress contributes to the progression of neurodegenerative diseases of the central and peripheral nervous systems, including Alzheimer’s disease, Parkinson’s disease, stroke, and diabetic neuropathy. Despite the greater capability of peripheral nerves to regenerate compared with those in the brain or spinal cord, chronic oxidative stress leads to irreversible neurodegeneration in peripheral nerves.”
Financial support for this research came from National Research Foundation of Korea (NRF) grant funded by the Korea government.
Our news journalists obtained a quote from the research from Kyung Hee University, “Thus, many efforts have been made to defend against irreversible peripheral nerve degeneration and oxidative stress. Numerous phytochemicals have been revealed as antioxidants which neutralize free radicals and reduce peripheral neurocellular damage. Among them, polyphenols alleviate neurodegeneration by interacting with reactive oxygen species. Apigenin is a polyphenol found in plant-derived foods, including parsley, thyme, celery, and chamomile tea. Apigenin has been reported to exert antioxidative effects by scavenging free radicals. In particular, apigenin has a neuroprotective effect against oxidative stress in neurological disorders, such as cerebral ischemia. However, to date, no studies have shown an association of the inhibitory effect of apigenin with peripheral nerve degeneration. In this work, we showed that apigenin has a neuroprotective effect against peripheral nerve degeneration according to four key phenotypes: axonal degradation, myelin fragmentation, trans-dedifferentiation, and proliferation of Schwann cells via Krox20-and extracellular signal-regulated kinase-independent processes.”
According to the news editors, the research concluded: “Thus, apigenin could be a good candidate to treat peripheral neurodegenerative diseases.”
For more information on this research see: The natural plant flavonoid apigenin is a strong antioxidant that effectively delays peripheral neurodegenerative processes. Anatomical Science International, 2019;94(4):285-294. Anatomical Science International can be contacted at: Springer, 233 Spring Street, New York, NY 10013, USA. (Wiley-Blackwell - http://www.wiley.com/; Anatomical Science International - http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1447-073X)
Our news journalists report that additional information may be obtained by contacting J. Jung, Dept. of Anatomy and Neurobiology, College of Medicine, Kyung Hee University, 26, Kyungheedae-ro, Dongdaemun-gu, Seoul, 02447, South Korea. Additional authors for this research include J. Jung, N.Y. Jeong and H.J Chung.
The direct object identifier (DOI) for that additional information is: https://doi.org/10.1007/s12565-019-00486-2. This DOI is a link to an online electronic document that is either free or for purchase, and can be your direct source for a journal article and its citation.
Publisher contact information for the journal Anatomical Science International is: Springer, 233 Spring Street, New York, NY 10013, USA.
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