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Research from Seoul National University College of Medicine Reveals New Findings on Osteoporosis

NewsRx Women’s Health Daily


2019 SEP 10 (NewsRx) -- By a News Reporter-Staff News Editor at NewsRx Women’s Health Daily -- Data detailed on Musculoskeletal Diseases and Conditions - Osteoporosis have been presented. According to news reporting from Seoul, South Korea, by NewsRx journalists, research stated, “The diagnosis of osteoporosis is determined based on the lowest bone mineral density (BMD) T-score at the lumbar spine (LS) and hip. However, there are occasional marked discordances between the T-score of LS and femur neck (FN).”

The news correspondents obtained a quote from the research from the Seoul National University College of Medicine, “We aimed to examine the prevalence and characteristics of individuals with spine-femur BMD discordance using a nationwide survey. A total of 3233 men aged 50 years and 2915 postmenopausal women were included from the Korean National Health and Nutrition Examination Surveys (2008-2011). The spine-femur discordance was defined as a difference of 1.5 SD between LS and FN BMD. Subjects were divided into three groups: low LS (LS <FN), low FN (LS >FN), and no discordance. Four-hundred and seventeen men (12.9%) and two hundred and ninety women (10%) exhibited spine-femur BMD discordance. The prevalence of hypertension and diabetes was higher in men and women with low FN BMD than in any other group. Fasting plasma glucose and homeostasis model assessment of insulin resistance was the highest in subjects with low FN BMD among the three groups. Low FN BMD revealed higher serum parathyroid hormone and lower 25-hydroxyvitamin D3 levels compared to any other group in women, but this was not observed in men. Osteoporosis was prevalent in subjects with discordance in both genders, particularly, in those with low LS BMD (31.6% in men and 63.5% in women).”

According to the news reporters, the research concluded: “Given the high prevalence of spine-femur BMD discordance, low FN BMD may be associated with vitamin D deficiency and insulin resistance, but low LS BMD may present severe osteoporosis.”

For more information on this research see: Metabolic characteristics of subjects with spine-femur bone mineral density discordances: the Korean National Health and Nutrition Examination Survey (KNHANES 2008-2011). Journal of Bone and Mineral Metabolism, 2019;37(5):835-843. Journal of Bone and Mineral Metabolism can be contacted at: Springer, 233 Spring Street, New York, NY 10013, USA. (Springer -; Journal of Bone and Mineral Metabolism -

Our news journalists report that additional information may be obtained by contacting C.S. Shin, Dept. of Internal Medicine, College of Medicine, Seoul, South Korea. Additional authors for this research include J.H. Kim, J.H. Lee, S.W. Kim and C.S Shin.

The direct object identifier (DOI) for that additional information is: This DOI is a link to an online electronic document that is either free or for purchase, and can be your direct source for a journal article and its citation.

Publisher contact information for the Journal of Bone and Mineral Metabolism is: Springer, 233 Spring Street, New York, NY 10013, USA.

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