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Findings in the Area of Vitamin and Nutrition Research Reported from Isfahan University of Medical Sciences (The effect of omega-3 and vitamin E on oxidative stress and inflammation: Systematic review and meta-analysis of randomized controlled ...)

Middle East Daily

09-12-19

2019 SEP 11 (NewsRx) -- By a News Reporter-Staff News Editor at Middle East Daily -- Research findings on Diet and Nutrition - Vitamin and Nutrition Research are discussed in a new report. According to news reporting out of Isfahan, Iran, by NewsRx editors, research stated, “Several studies have investigated the effect of omega-3 fatty acids and vitamin E on oxidative stress and inflammation, but their findings are inconsistent. The aim of this meta-analysis is to elucidate the overall effects of co-supplementation with omega-3 fatty acids and vitamin E on oxidative stress and inflammation.”

Our news journalists obtained a quote from the research from the Isfahan University of Medical Sciences, “We searched titles, abstracts, and keywords of relevant articles indexed in PubMed, ISI, Scopus, and Google Scholar databases up to December 2018 to identify eligible RCT studies. Random effects model was used to estimate the pooled effect of co-supplementation with omega-3 fatty acids and vitamin E on oxidative stress and inflammation. Overall, 7 RCTs with 504 participants were included in this meta-analysis. We found that co-supplementation with omega-3 fatty acids and vitamin E decreased hs-CRP (weighed mean difference (WMD)=-2.15 mg/L; 95% CI: -3.40, -0.91 mg/L; p<0.001) concentrations and increased total antioxidant capacity (TAC) (WMD=92.87 mmol/L; 95% CI: 31.97, 153.77 mmol/L; p=0.03), and nitric oxide levels (NO) (WMD: 6.95 mmol/L; 95% CI: 3.86, 10.04, p<0.001) compared with control group. Omega-3 fatty acids and vitamin E had no significant effect on malondialdehyde (MDA) (WMD: 1.54 mmol/L; 95% CI: -1.29, 4.36; p=0.196), and glutathione (GSH) (WMD: 20.87 mmol/L; 95% CI: -20.04, 61.6, p=0.31) levels.”

According to the news editors, the research concluded: “The present meta-analysis found that omega-3 fatty acids and vitamin E co-supplementation significantly decreased hs-CRP and increased NO and TAC, although it had no significant effect on MDA and GSH.”

For more information on this research see: The effect of omega-3 and vitamin E on oxidative stress and inflammation: Systematic review and meta-analysis of randomized controlled trials. International Journal for Vitamin and Nutrition Research, 2019;():1-11. International Journal for Vitamin and Nutrition Research can be contacted at: Verlag Hans Huber, Langgass-Strasse 76, CH-3000 Bern 9, Switzerland.

Our news journalists report that additional information may be obtained by contacting S.P. Moosavian, Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran. Additional authors for this research include A. Arab, S. Mehrabani, S. Moradi and M. Nasirian.

The direct object identifier (DOI) for that additional information is: https://doi.org/10.1024/0300-9831/a000599. This DOI is a link to an online electronic document that is either free or for purchase, and can be your direct source for a journal article and its citation.

Publisher contact information for the International Journal for Vitamin and Nutrition Research is: Verlag Hans Huber, Langgass-Strasse 76, CH-3000 Bern 9, Switzerland.

(Our reports deliver fact-based news of research and discoveries from around the world.)

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