Lower incidence of hypertension associated with greater omega-3 fatty acid intake
Tuesday October 4, 2011. The August, 2011 issue of the Journal of Internal Medicine published the findings of American researchers of a reduction in the incidence of high blood pressure in men and women who consumed higher amounts of long-chain omega-3 polyunsaturated fatty acids from fish. While the cardiovascular benefits of long-chain omega-3 fatty acids (which include EPA and DHA) are well known, the current research sought to determine potential interactions with the body's levels of selenium and mercury, elements that also occur in fish.
The study involved 4,508 men and women enrolled in 1985 in the ongoing Coronary Artery Risk Development in Young Adults (CARDIA) Study. Dr Ka He of the University of North Carolina in Chapel Hill and colleagues utilized responses to dietary questionnaires conducted upon enrollment and at the seven and twenty year follow-up examinations to determine average omega-3 fatty acid intake. Blood pressure was measured at all six follow-up visits, and incidences of high blood pressure or initiation of antihypertensive medication were noted. Selenium and mercury levels were determined by measuring the amounts contained in toenail clippings collected in 1987.
Dr He's team found a 35 percent lower adjusted risk of developing hypertension among men and women whose EPA and DHA levels were among the top 25 percent in comparison with those whose intake was among the lowest fourth. When the fatty acids were separately evaluated, DHA was associated with the greatest protective effect. The benefit for omega-3 fatty acids appeared to be greater among those with higher selenium and lower mercury levels.
"To the best of our knowledge, no study has investigated three-way interactions of selenium, mercury and long-chain omega-3 polyunsaturated fatty acids in relation to incidence of hypertension," the authors write. "The possible mechanisms explaining the modification of selenium and mercury on the antihypertensive effect of long-chain omega-3 polyunsaturated fatty acids may lie in that both selenium and mercury are somehow involved in the process of oxidative stress and cardiac function through the same pathway by which long-chain omega-3 polyunsaturated fatty acids regulate blood pressure."
"Additional studies are warranted to elucidate the complex interactions amongst selenium, mercury and long-chain omega-3 polyunsaturated fatty acids, three important components in fish, in terms of hypertension prevention," they conclude.
A report published online on August 1, 2011 in the journal Pediatrics reveals the finding of researchers from Rollins School of Public Health at Emory University and the Instituto Nacional de Salud Pública in Cuernavaca, Mexico of a protective effect for supplemental docosahexaenoic acid (DHA) against colds in infants when administered to their mothers during pregnancy. Docosahexaenoic acid is a long-chain polyunsaturated fatty acid that has been shown to improve immune function as well as provide numerous other health benefits.
In a randomized trial, 1,100 pregnant women residing in Mexico were given 400 milligrams of DHA derived from algae or a placebo from the 18th to 22 week of gestation until the birth of their infants. The occurrence of illness symptoms were reported by caregivers when the infants were one, three and six months of age.
At one month of age, combined cold symptoms were 24 percent lower among infants whose mothers received DHA than in those mothers who did not receive it. The incidence of cough, phlegm and wheezing was reduced by 26 percent, 15 percent and 30 percent in the DHA group. At three months of age, children born to mothers who received DHA spent 14 percent less time ill, and at six months, the group had a shorter duration of fever, nasal secretions, breathing difficulties, rash and other illness.
"This is a large scale, robust study that underscores the importance of good nutrition during pregnancy," commented lead researcher Usha Ramakrishnan, PhD, who is an associate professor at the Hubert Department of Global Health at Emory's Rollins School of Public Health. "Our findings indicate that pregnant women taking 400 mg of DHA are more likely to deliver healthier infants."
Taurine is a conditionally essential, sulfur-containing amino acid produced from cysteine by the body. It is found abundantly in the body, particularly throughout the excitable tissues of the central nervous system, where it is thought to have a regulating influence. Taurine can promote optimal blood flow to nervous tissue. It also appears to play an important role in many physiological processes, such as osmoregulation, immunomodulation and bile salt formation.
This supplement should be taken in conjunction with a healthy diet and regular exercise program. Individual results are not guaranteed and results may vary.
The information provided on this site is for informational purposes only and is not intended as a substitute for advice from your physician or other health care professional or any information contained on or in any product label or packaging. You should not use the information on this site for diagnosis or treatment of any health problem or for prescription of any medication or other treatment. You should consult with a healthcare professional before starting any diet, exercise or supplementation program, before taking any medication, or if you have or suspect you might have a health problem. You should not stop taking any medication without first consulting your physician.
If you are not 100% satisfied with any purchase made directly from Life Extension®, just return your purchase within 12 months of original purchase date and we will either replace the product for you, credit your original payment method or credit your Life Extension account for the full amount of the original purchase price (less shipping and handling).
These statements have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure, or prevent any disease.