Free Shipping on All Orders $75 Or More!

Your Trusted Brand for Over 35 Years

Health Protocols



Aapro MS, Bohlius J, Cameron DA., et al. 2010 update of EORTC guidelines for the use of granulocyte-colony stimulating factor to reduce the incidence of chemotherapy-induced febrile neutropenia in adult patients with lymphoproliferative disorders and solid tumours. Eur J Cancer. 2011;47(1):8-32.

Aarts MJ, Peters FP, Mandigers CM, et al. Primary granulocyte colony-stimulating factor prophylaxis during the first two cycles only or throughout all chemotherapy cycles in patients with breast cancer at risk for febrile neutropenia. J. Clin Oncol. 2013;31(34):4290-6.

Abd El-Atti S, Wasicek K, Mark S, Hegazi R. Use of probiotics in the management of chemotherapy-induced diarrhea: a case study. JPEN J Parenter Enteral Nutr. 2009 Sep-Oct;33(5):569-70.

Abdallah HM, Al-Abd AM, El-Dine RS, El-Halawany AM. P-glycoprotein inhibitors of natural origin as potential tumor chemo-sensitizers: A review. J Adv Res. Jan 2015;6(1):45-62.

Abdullah LN, Chow EK. Mechanisms of chemoresistance in cancer stem cells. Clin Transl Med. 2013;2(1):3.

ACS. American Cancer Society. A Guide to Chemotherapy. Available at: Last updated 6/9/2015. Accessed 2/16/2017.

ACS. American Cancer Society. Different types of chemotherapy drugs. Available at: Last updated 2/7/2013a. Accessed 2/16/2017.

ACS. American Cancer Society. Find Support & Treatment page. Hyperthermia to Treat Cancer. Available at: Last updated 6/24/2013b. Accessed 2/16/2017.

ACS. American Cancer Society. How Chemotherapy Drugs Work. Copyright 2017a. Accessed 2/21/2017.

ACS. American Cancer Society. Treatments & Side Effects: Central Venous Catheters. Copyright 2017b. Accessed 2/20/2017.

ACS. American Cancer Socity. Find Support & Treatment page. Oral Chemotherapy: What You Need to Know. Available at: Last updated 7/17/2014. Accessed 2/16/2017.

Ajani JA, Mangu PB, Burstein HJ. Peek before you treat? Is it a fantasy or reality? J Oncol Pract. 2011;7(5):338-9.

Akagi J, Baba H. PSK may suppress CD57(+) T cells to improve survival of advanced gastric cancer patients. Int J Clin Oncol. 2010;15(2):145-52.

Akbulut S, Elbe H, Eris C, Dogan Z, Toprak G, Otan E, . . . Turkoz Y. Cytoprotective effects of amifostine, ascorbic acid and N-acetylcysteine against methotrexate-induced hepatotoxicity in rats. World journal of gastroenterology: WJG. Aug 7 2014;20(29):10158-10165.

Alam SS, Hafiz NA, Abd El-Rahim AH. Protective role of taurine against genotoxic damage in mice treated with methotrexate and tamoxfine. Environmental toxicology and pharmacology. Jan 2011;31(1):143-152.

Aleisa AM, Al-Majed AA, Al-Yahya AA, Al-Rejaie SS, Bakheet SA, Al-Shabanah OA, Sayed-Ahmed MM. Reversal of cisplatin-induced carnitine deficiency and energy starvation by propionyl-L-carnitine in rat kidney tissues. Clinical and experimental pharmacology & physiology. Dec 2007;34(12):1252-1259.

Alpsoy S, Aktas C, Uygur R, et al. Antioxidant and anti-apoptotic effects of onion (Allium cepa) extract on doxorubicin-induced cardiotoxicity in rats. J Appl Toxicol. 2013;33(3):202-8.

Alyane M, Kebsa LB, Boussenane H, Rouibah H, Lahouel M. Cardioprotective effects and mechanism of action of polyphenols extracted from propolis against doxorubicin toxicity. Pak J Pharm Sci. 2008;21(3):201-9.

Amara S. Oral glutamine for the prevention of chemotherapy-induced peripheral neuropathy. Ann Pharmacother. 2008 Oct;42(10):1481-5.

Anderl J, Faulstich H, Hechler T, Kulke M. Antibody-drug conjugate payloads. Methods Mol Biol. 2013;1045:51-70.

Andreotti PE, Cree IA, Kurbacher CM, Hartmann DM, Linder D, Harel G, . . . et al. Chemosensitivity testing of human tumors using a microplate adenosine triphosphate luminescence assay: clinical correlation for cisplatin resistance of ovarian carcinoma. Cancer research. Nov 15 1995;55(22):5276-5282.

Antman K, Crowley J, Balcerzak SP, Rivkin SE, Weiss GR, Elias A, Natale RB, Cooper RM, Barlogie B, Trump DL, et al. An intergroup phase III randomized study of doxorubicin and dacarbazine with or without ifosfamide and mesna in advanced soft tissue and bone sarcomas. J Clin Oncol. 1993 Jul;11(7):1276-85.

Antony B, Merina B, Iyer VS, Judy N, Lennertz K, Joyal S. A Pilot Cross-Over Study to Evaluate Human Oral Bioavailability of BCM-95CG (Biocurcumax), A Novel Bioenhanced Preparation of Curcumin. Indian J Pharm Sci. 2008;70(4):445-449.

Apelseth TO, Hervig T, Bruserud O. Current practice and future directions for optimization of platelet transfusions in patients with severe therapy-induced cytopenia. Blood Rev. 2011 May;25(3):113-22.

Argun M, Uzum K, Sonmez MF, Ozyurt A, Derya K, Cilenk KT, . . . Narin N. Cardioprotective effect of metformin against doxorubicin cardiotoxicity in rats. Anatolian journal of cardiology. Apr 2016;16(4):234-241.

Argyriou AA, Kyritsis AP, Makatsoris T, Kalofonos HP. Chemotherapy-induced peripheral neuropathy in adults: a comprehensive update of the literature. Cancer Manag Res. 2014;6:135-47.

Arienti C, Tesei A, Verdecchia GM, Framarini M, Virzi S, Grassi A, . . . Zoli W. Role of conventional chemosensitivity test and tissue biomarker expression in predicting response to treatment of peritoneal carcinomatosis from colon cancer. Clinical colorectal cancer. Jun 2013;12(2):122-127.

Arienti C, Tesei A, Verdecchia GM, Framarini M, Virzì S, Grassi A, Scarpi E, Turci L, Silvestrini R, Amadori D, Zoli W. Peritoneal carcinomatosis from ovarian cancer: chemosensitivity test and tissue markers as predictors of response to chemotherapy. J Transl Med. 2011 Jun 20;9:94.

Asano S, Ueno K, Niitani M, Uemura K, Murakami Y, Sudo T, Hirata E, Suzuki T, Tsutani Y, Narahara H, Kataoka T. [Examination of taste threshold and serum zinc level change after chemotherapy]. Gan To Kagaku Ryoho. 2012 Sep;39(9):1389-93.

ASCO. American Society of Clinical Oncology. Navigating Cancer Care. Catheters and Ports in Cancer Treatment. Available at: 2/2013. Accessed 1/20/2015.

ASCO. American Society of Clinical Oncology. Navigating Cancer Care. What is Chemotherapy? Available at: Copyright 2014. Accessed 1/7/2015.

Ashour AE, Sayed-Ahmed MM, Abd-Allah AR, Korashy HM, Maayah ZH, Alkhalidi H, . . . Alhaider A. Metformin rescues the myocardium from doxorubicin-induced energy starvation and mitochondrial damage in rats. Oxid Med Cell Longev. 2012;2012:434195.

Ashour OM, Elberry AA, Alahdal A, et al. Protective effect of bilberry (Vaccinium myrtillus) against doxorubicin-induced oxidative cardiotoxicity in rats. Med Sci Monit. 2011;17(4):BR110-5.

Asvadi I, Hajipour B, Asvadi A, Asl NA, Roshangar L, Khodadadi A. Protective effect of pentoxyfilline in renal toxicity after methotrexate administration. Eur Rev Med Pharmacol Sci. 2011 Sep;15(9):1003-9.

Attarian H, Rezvani H, Ghadyani M, Eshaghi F. Consolidation Chemotherapy with Docetaxel after Platinum-Based Chemotherapy in Patients with Non-Small Cell Lung Cancer: A Preliminary Report. Tanaffos. 2011;10(3):20-23.

Attili-Qadri S, Karra N, Nemirovski A, Schwob O, Talmon Y, Nassar T, Benita S. Oral delivery system prolongs blood circulation of docetaxel nanocapsules via lymphatic absorption. Proceedings of the National Academy of Sciences of the United States of America. 2013;110(43):17498-17503.

Avila JG. Pharmacologic treatment of constipation in cancer patients. Cancer Control. 2004 May-Jun;11(3 Suppl):10-8.

Bagchi D, Ray SD, Bagchi M, Preuss HG, Stohs SJ. Mechanistic pathways of antioxidant cytoprotection by a novel IH636 grape seed proanthocyanidin extract. Indian J Exp Biol. 2002;40(6):717-726.

Bagnyukova TV, Serebriiskii IG, Zhou Y, Hopper-Borge EA, Golemis EA, Astsaturov I. Chemotherapy and signaling: How can targeted therapies supercharge cytotoxic agents? Cancer Biol Ther. 2010 Nov 1;10(9):839-53.

Bahl A, Bakhshi S. Metronomic chemotherapy in progressive pediatric malignancies: old drugs in new package. Indian journal of pediatrics. Dec 2012;79(12):1617-1622.

Ballard KS, Homesley HD, Hodson C, Presant CA, Rutledge J, Hallquist A, Perree M. Endometrial carcinoma in vitro chemosensitivity testing of single and combination chemotherapy regimens using the novel microculture kinetic apoptosis assay: implications for endometrial cancer treatment. Journal of gynecologic oncology. Mar 2010;21(1):45-49.

Bang MH, Van Riep T, Thinh NT, Song le H, Dung TT, Van Truong L, . . . Ghoneum M. Arabinoxylan rice bran (MGN-3) enhances the effects of interventional therapies for the treatment of hepatocellular carcinoma: a three-year randomized clinical trial. Anticancer research. Dec 2010;30(12):5145-5151.

Bansal T, Jaggi M, Khar RK, Talegaonkar S. Emerging significance of flavonoids as P-glycoprotein inhibitors in cancer chemotherapy. Journal of pharmacy & pharmaceutical sciences: a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques. 2009;12(1):46-78.

Barni S, Lissoni P, Cazzaniga M, et al. A randomized study of low-dose subcutaneous interleukin-2 plus melatonin versus supportive care alone in metastatic colorectal cancer patients progressing under 5-fluorouracil and folates. Oncology. 1995;52(3):243-5.

Bar-Sela G, Wollner M, Hammer L, Agbarya A, Dudnik E, Haim N. Mistletoe as complementary treatment in patients with advanced non-small-cell lung cancer treated with carboplatin-based combinations: a randomised phase II study. Eur J Cancer. 2013 Mar;49(5):1058-64.

Bartal A, Matrai Z, Szucs A, Liszkay G. [Main treatment and preventive measures for hand-foot syndrome, a dermatologic side effect of cancer therapy]. Magyar onkologia. Jun 2011;55(2):91-98.

Barton DL, Liu H, Dakhil SR, Linquist B, Sloan JA, Nichols CR, . . . Loprinzi CL. Wisconsin Ginseng (Panax quinquefolius) to improve cancer-related fatigue: a randomized, double-blind trial, N07C2. Journal of the National Cancer Institute. Aug 21 2013;105(16):1230-1238.

Baszkowsky LS, Supko JG, Chabner BA. Principles of Chemotherapy. In: Gunderson LL, Tepper JE, eds. Clinical Radiation Oncology, 3rd Edition: Saunders, An Imprint of Elsevier Inc.; 2012:165-179.

Bava SV, Sreekanth CN, Thulasidasan AK, Anto NP, Cheriyan VT, Puliyappadamba VT, . . . Anto RJ. Akt is upstream and MAPKs are downstream of NF-kappaB in paclitaxel-induced survival signaling events, which are down-regulated by curcumin contributing to their synergism. The international journal of biochemistry & cell biology. Mar 2011;43(3):331-341.

Beck A, Lambert J, Sun M, Lin K. Fourth World Antibody-Drug Conjugate Summit: February 29-March 1, 2012, Frankfurt, Germany. mAbs. Nov-Dec 2012;4(6):637-647.

Beck PL, Wong JF, Li Y, Swaminathan S, Xavier RJ, Devaney KL, Podolsky DK. Chemotherapy- and radiotherapy-induced intestinal damage is regulated by intestinal trefoil factor. Gastroenterology. Mar 2004;126(3):796-808.

Bedell CH. A changing paradigm for cancer treatment: the advent of new oral chemotherapy agents. Clin J Oncol Nurs. 2003;7(6 Suppl):5-9.

Beer TM, Bubalo JS. Complications of chemotherapy for prostate cancer. Seminars in urologic oncology. Aug 2001;19(3):222-230.

Beer TM, Ryan CW, Venner PM, et al.; ASCENT Investigators. Double-blinded randomized study of high-dose calcitriol plus docetaxel compared with placebo plus docetaxel in androgen-independent prostate cancer: a report from the ASCENT Investigators. J Clin Oncol. 2007;25(6):669-74.

Beijers AJ, Jongen JL, Vreugdenhil G. Chemotherapy-induced neurotoxicity: the value of neuroprotective strategies. Neth J Med. 2012 Jan;70(1):18-25.

Belcaro G, Hosoi M, Pellegrini L, Appendino G, Ippolito E, Ricci A, . . . Togni S. A controlled study of a lecithinized delivery system of curcumin (Meriva(R)) to alleviate the adverse effects of cancer treatment. Phytotherapy research : PTR. Mar 2014;28(3):444-450.

Bernhardson BM, Tishelman C, Rutqvist LE. Self-reported taste and smell changes during cancer chemotherapy. Supportive care in cancer: official journal of the Multinational Association of Supportive Care in Cancer. Mar 2008;16(3):275-283.

Berthiaume JM, Oliveira PJ, Fariss MW, Wallace KB. Dietary vitamin E decreases doxorubicin-induced oxidative stress without preventing mitochondrial dysfunction. Cardiovascular toxicology. 2005;5(3):257-267.

Bhatt V, Saleem A. Drug-Induced Neutropenia – Pathophysiology, Clinical Features, and Management. Annals of Clinical & Laboratory Science. 2004;34(2):131-137.

Bianchi G, Vitali G, Caraceni A, Ravaglia S, Capri G, Cundari S, . . . Gianni L. Symptomatic and neurophysiological responses of paclitaxel- or cisplatin-induced neuropathy to oral acetyl-L-carnitine. European journal of cancer (Oxford, England: 1990). Aug 2005;41(12):1746-1750.

Biswal BM, Sulaiman SA, Ismail HC, Zakaria H, Musa KI. Effect of Withania somnifera (Ashwagandha) on the development of chemotherapy-induced fatigue and quality of life in breast cancer patients. Integr Cancer Ther. 2013 Jul;12(4):312-22.

Black HS. Interaction of ascorbic acid and tocopherol on beta-carotene modulated carcinogenesis. Hemoglobin. Jun 2010;34(3):284-290.

Block KI, Koch AC, Mead MN, Tothy PK, Newman RA, Gyllenhaal C. Impact of antioxidant supplementation on chemotherapeutic efficacy: a systematic review of the evidence from randomized controlled trials. Cancer treatment reviews. Aug 2007;33(5):407-418.

Block KI. Antioxidants and cancer therapy: furthering the debate. Integrative cancer therapies. Dec 2004;3(4):342-348.

Bodnar L, Wcislo G, Gasowska-Bodnar A, Synowiec A, Szarlej-Wcislo K, Szczylik C. Renal protection with magnesium subcarbonate and magnesium sulphate in patients with epithelial ovarian cancer after cisplatin and paclitaxel chemotherapy: a randomised phase II study. European journal of cancer (Oxford, England: 1990). Nov 2008;44(17):2608-2614.

Boeck S, Ankerst DP, Heinemann V. The role of adjuvant chemotherapy for patients with resected pancreatic cancer: systematic review of randomized controlled trials and meta-analysis. Oncology. 2007;72(5-6):314-321.

Boghdady NA. Antioxidant and antiapoptotic effects of proanthocyanidin and ginkgo biloba extract against doxorubicin-induced cardiac injury in rats. Cell biochemistry and function. Jun 2013;31(4):344-351.

Bogliun G, Marzorati, L., Marzola, M., Miceli, M.D., Cantù, M.G. and Cavaletti, G. Neurotoxicity of cisplatin +/− reduced glutathione in the first-line treatment of advanced ovarian cancer. International Journal of Gynecological Cancer, 6: 415–419. 1996.

Bohlius J, Tonia T, Nuesch E, Juni P, Fey MF, Egger M, Bernhard J. Effects of erythropoiesis-stimulating agents on fatigue- and anaemia-related symptoms in cancer patients: systematic review and meta-analyses of published and unpublished data. British journal of cancer. Jul 8 2014;111(1):33-45.

Boros LG, Nichelatti M, Shoenfeld Y. Fermented wheat germ extract (Avemar) in the treatment of cancer and autoimmune diseases. Annals of the New York Academy of Sciences. 2005;1051(1):529-542.

Bougnoux P, Hajjaji N, Ferrasson MN, Giraudeau B, Couet C, Le Floch O. Improving outcome of chemotherapy of metastatic breast cancer by docosahexaenoic acid: a phase II trial. British journal of cancer. Dec 15 2009;101(12):1978-1985.

Boumendjel A, Macalou S, Valdameri G, Pozza A, Gauthier C, Arnaud O, Nicolle E, Magnard S, Falson P, Terreux R, Carrupt PA, Payen L, Di Pietro A. Targeting the multidrug ABCG2 transporter with flavonoidic inhibitors: in vitro optimization and in vivo validation. Curr Med Chem. 2011;18(22):3387-3401.

Bove L, Picardo M, Maresca V, Jandolo B, Pace A. A pilot study on the relation between cisplatin neuropathy and vitamin E. Journal of experimental & clinical cancer research: CR. Jun 2001;20(2):277-280.

Boyland E. Critical review of problems of chemotherapy. Proc R Soc Med. 1963;56:640-2.

Bozkurt Duman B, Kara B, Oguz Kara I, Demiryurek H, Aksungur E. Hand-foot syndrome due to sorafenib in hepatocellular carcinoma treated with vitamin E without dose modification; a preliminary clinical study. J BUON. 2011 Oct-Dec;16(4):759-64.

Brace CL. Microwave tissue ablation: biophysics, technology, and applications. Critical reviews in biomedical engineering. 2010;38(1):65-78.

Brandhorst S, Wei M, Hwang S, Morgan TE, Longo VD. Short-term calorie and protein restriction provide partial protection from chemotoxicity but do not delay glioma progression. Experimental gerontology. Oct 2013;48(10):1120-1128.

Brandhorst S, Choi IY, Wei M, et al. A periodic diet that mimics fasting promotes multi-system regeneration, enhanced cognitive performance, and healthspan. Cell Metab. 2015;22(1):86-99.

Brock N. The development of mesna for the inhibition of urotoxic side effects of cyclophosphamide, ifosfamide, and other oxazaphosphorine cytostatics. Recent Results Cancer Res. 1980;74:270-8.

Brown GM. Light, melatonin and the sleep-wake cycle. Journal of psychiatry & neuroscience : JPN. Nov 1994;19(5):345-353.

Calder PC. n-3 fatty acids, inflammation, and immunity--relevance to postsurgical and critically ill patients. Lipids. Dec 2004;39(12):1147-1161.

Caldwell B, Aldington S, Weatherall M, Shirtcliffe P, Beasley R. Risk of cardiovascular events and celecoxib: a systematic review and meta-analysis. Journal of the Royal Society of Medicine. Mar 2006;99(3):132-140.

Calviello G, Serini S, Piccioni E, Pessina G. Antineoplastic effects of n-3 polyunsaturated fatty acids in combination with drugs and radiotherapy: preventive and therapeutic strategies. Nutrition and cancer. 2009;61(3):287-301.

Campone M, Berton-Rigaud D, Joly-Lobbedez F, Baurain JF, Rolland F, Stenzl A, Fabbro M, van Dijk M, Pinkert J, Schmelter T, de Bont N, Pautier P. A double-blind, randomized phase II study to evaluate the safety and efficacy of acetyl-L-carnitine in the prevention of sagopilone-induced peripheral neuropathy. Oncologist. 2013;18(11):1190-1.

Campos MI, Campos CN, Aarestrup FM, Aarestrup BJ. Oral mucositis in cancer treatment: Natural history, prevention and treatment. Mol Clin Oncol. 2014 May;2(3):337-340.

Capizzi RL. Amifostine reduces the incidence of cumulative nephrotoxicity from cisplatin: laboratory and clinical aspects. Seminars in oncology. Apr 1999;26(2 Suppl 7):72-81.

Cardinale D, Colombo A, Sandri MT, Lamantia G, Colombo N, Civelli M, Martinelli G, Veglia F, Fiorentini C, Cipolla CM. Prevention of high-dose chemotherapy-induced cardiotoxicity in high-risk patients by angiotensin-converting enzyme inhibition. Circulation. 2006 Dec 5;114(23):2474-81.

Carey PJ. Drug-induced myelosuppression: diagnosis and management. Drug safety: an international journal of medical toxicology and drug experience. 2003;26(10):691-706.

Cascinu S, Catalano V, Cordella L, Labianca R, Giordani P, Baldelli AM, . . . Catalano G. Neuroprotective effect of reduced glutathione on oxaliplatin-based chemotherapy in advanced colorectal cancer: a randomized, double-blind, placebo-controlled trial. Journal of clinical oncology: official journal of the American Society of Clinical Oncology. Aug 15 2002;20(16):3478-3483.

Cascinu S, Cordella L, Del Ferro E, Fronzoni M, Catalano G. Neuroprotective effect of reduced glutathione on cisplatin-based chemotherapy in advanced gastric cancer: a randomized double-blind placebo-controlled trial. J Clin Oncol. 1995 Jan;13(1):26-32.

Catania A, Barrajon-Catalan E, Nicolosi S, Cicirata F, Micol V. Immunoliposome encapsulation increases cytotoxic activity and selectivity of curcumin and resveratrol against HER2 overexpressing human breast cancer cells. Breast Cancer Res Treat. Aug 2013;141(1):55-65.

Cavaletti G, Marmiroli P. Chemotherapy-induced peripheral neurotoxicity. Current opinion in neurology. Oct 2015;28(5):500-507.

CCS. Canadian Cancer Society. Cancer information page. Side effects of chemotherapy. Copyright 2017. Accessed 1/13/2017.

CCS. Canadian Cancer Society. How Chemotherapy Works. Drug Resistance. Available at: Accessed 08/25/2014.

Cerchietti LC, Navigante AH, Castro MA. Effects of eicosapentaenoic and docosahexaenoic n-3 fatty acids from fish oil and preferential Cox-2 inhibition on systemic syndromes in patients with advanced lung cancer. Nutrition and cancer. 2007;59(1):14-20.

Cerea G, Vaghi M, Ardizzoia A, et al. Biomodulation of cancer chemotherapy for metastatic colorectal cancer: a randomized study of weekly low-dose irinotecan alone versus irinotecan plus the oncostatic pineal hormone melatonin in metastatic colorectal cancer patients progressing on 5-fluorouracil-containing combinations. Anticancer Res. 2003;23(2C):1951-4.

Chabner BA, Thompson EC. Merck Manuals. The Merck Manual Professional Edition. Modalities of Cancer Therapy. Chemotherapy. Available at modalities_of_cancer_therapy.html. Last updated 9/2013a. Accessed 08/27/2014.

Chabner BA, Thompson EC. Merck Manuals. The Merck Manual Professional Edition. Principles of Cancer Therapy. Cachexia and Cancer. Available at: cachexia_in_cancer.html. Last updated 9/2013b. Accessed 10/27/2014.

Chae YK, Arya A, Malecek MK, Shin DS, Carneiro B, Chandra S, . . . Giles F. Repurposing metformin for cancer treatment: current clinical studies. Oncotarget. Jun 28 2016;7(26):40767-40780.

Chaurasia S, Patel RR, Chaubey P, Kumar N, Khan G, Mishra B. Lipopolysaccharide based oral nanocarriers for the improvement of bioavailability and anticancer efficacy of curcumin. Carbohydrate polymers. Oct 5 2015;130:9-17.

Chaveli-Lopez B, Bagan-Sebastian JV. Treatment of oral mucositis due to chemotherapy. Journal of clinical and experimental dentistry. Apr 2016;8(2):e201-209.

Chemocare. How Long is Chemotherapy Given? Copyright 2017. Accessed 3/17/2017.

Chen G, Xu S, Renko K, Derwahl M. Metformin inhibits growth of thyroid carcinoma cells, suppresses self-renewal of derived cancer stem cells, and potentiates the effect of chemotherapeutic agents. J Clin Endocrinol Metab. 2012;97(4):E510-20.

Chen H, Landen CN, Li Y, Alvarez RD, Tollefsbol TO. Enhancement of Cisplatin-Mediated Apoptosis in Ovarian Cancer Cells through Potentiating G2/M Arrest and p21 Upregulation by Combinatorial Epigallocatechin Gallate and Sulforaphane. Journal of oncology. 2013;2013:872957.

Chen M, Zhang L, Wang Q, Shen J. Pyridoxine for prevention of hand-foot syndrome caused by chemotherapy: a systematic review. PLoS One. 2013;8(8):e72245.

Chen N, Aleksa K, Woodland C, Rieder M, Koren G. N-Acetylcysteine prevents ifosfamide-induced nephrotoxicity in rats. British journal of pharmacology. Apr 2008;153(7):1364-1372.

Chen N, Aleksa K, Woodland C, Rieder M, Koren G. The effect of N-acetylcysteine on ifosfamide-induced nephrotoxicity: in vitro studies in renal tubular cells. Translational research : the journal of laboratory and clinical medicine. Jul 2007;150(1):51-57.

Chen N, Hanly L, Rieder M, Yeger H, Koren G. The effect of N-acetylcysteine on the antitumor activity of ifosfamide. Canadian journal of physiology and pharmacology. May 2011;89(5):335-343.

Chen S, Wang Z, Huang Y, O'Barr SA, Wong RA, Yeung S, Chow MS. Ginseng and anticancer drug combination to improve cancer chemotherapy: a critical review. Evid Based Complement Alternat Med. 2014;2014:168940.

Chen YZ, Li ZD, Gao F, et al. Effects of combined Chinese drugs and chemotherapy in treating advanced non-small cell lung cancer. Chin J Integr Med. 2009;15(6):415-9.

Cheng CW, Adams GB, Perin L, Wei M, Zhou X, Lam BS, . . . Longo VD. Prolonged fasting reduces IGF-1/PKA to promote hematopoietic-stem-cell-based regeneration and reverse immunosuppression. Cell stem cell. Jun 5 2014;14(6):810-823.

Cheng CW, Fan W, Ko SG, Song L, Bian ZX. Evidence-based management of herb-drug interaction in cancer chemotherapy. Explore (New York, N.Y.). Sep-Oct 2010;6(5):324-329.

Chi KH, Chiou TJ, Li CP, Chen SY, Chao Y. MS-20, a chemotherapeutical adjuvant, reduces chemo-associated fatigue and appetite loss in cancer patients. Nutrition and cancer. 2014;66(7):1211-1219.

Chien TJ, Liu CY, Hsu CH. Integrating acupuncture into cancer care. Journal of traditional and complementary medicine. Oct 2013;3(4):234-239.

Choi EK, Kim IR, Chang O, Kang D, Nam SJ, Lee JE, Lee SK, Im YH, Park YH, Yang JH, Cho J. Impact of chemotherapy-induced alopecia distress on body image, psychosocial well-being, and depression in breast cancer patients. Psychooncology. 2014 Mar 24. doi: 10.1002/pon.3531

Choi MR, Solid CA, Chia VM, Blaes AH, Page JH, Barron R, Arneson TJ. Granulocyte colony-stimulating factor (G-CSF) patterns of use in cancer patients receiving myelosuppressive chemotherapy. Supportive care in cancer: official journal of the Multinational Association of Supportive Care in Cancer. Jun 2014;22(6):1619-1628.

Chu SH, Lee YJ, Lee ES, Geng Y, Wang XS, Cleeland CS. Current use of drugs affecting the central nervous system for chemotherapy-induced peripheral neuropathy in cancer patients: a systematic review. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer. Feb 2015;23(2):513-524.

Chuang-Xin L, Wen-Yu W, Yao C, Xiao-Yan L, Yun Z. Quercetin enhances the effects of 5-fluorouracil-mediated growth inhibition and apoptosis of esophageal cancer cells by inhibiting NF-kappaB. Oncology letters. Oct 2012;4(4):775-778.

Cobo M, Isla D, Massuti B, Montes A, Sanchez JM, Provencio M, Viñolas N, Paz-Ares L, Lopez-Vivanco G, Muñoz MA, Felip E, Alberola V, Camps C, Domine M, Sanchez JJ, Sanchez-Ronco M, Danenberg K, Taron M, Gandara D, Rosell R. Customizing cisplatin based on quantitative excision repair cross-complementing 1 mRNA expression: a phase III trial in non-small-cell lung cancer. J Clin Oncol. 2007 Jul 1;25(19):2747-54.

Cohen MH, Dagher R, Griebel DJ, Ibrahim A, Martin A, Scher NS, Sokol GH, Williams GA, Pazdur R. U.S. Food and Drug Administration drug approval summaries: imatinib mesylate, mesna tablets, and zoledronic acid. Oncologist. 2002;7(5):393-400.

Coiffier B, Altman A, Pui CH, Younes A, Cairo MS. Guidelines for the management of pediatric and adult tumor lysis syndrome: an evidence-based review. Journal of clinical oncology: official journal of the American Society of Clinical Oncology. Jun 1 2008;26(16):2767-2778.

Colombo N, Bini S, Miceli D, Bogliun G, Marzorati L, Cavaletti G, . . . Mangioni C. Weekly cisplatin +/- glutathione in relapsed ovarian carcinoma. International journal of gynecological cancer: official journal of the International Gynecological Cancer Society. Mar 1995;5(2):81-86.

Colombo PE, Milanezi F, Weigelt B, Reis-Filho JS. Microarrays in the 2010s: the contribution of microarray-based gene expression profiling to breast cancer classification, prognostication and prediction. Breast cancer research: BCR. 2011;13(3):212.

Colombo R, Moschini M. [Role of the combined regimen with local chemotherapy and Mw-induced hyperthermia for non-muscle invasive bladder cancer management. A systematic review]. Urologia. Apr-Jun 2013;80(2):112-119.

Conaway CC, Getahun SM, Liebes LL, Pusateri DJ, Topham DK, Botero-Omary M, Chung FL. Disposition of glucosinolates and sulforaphane in humans after ingestion of steamed and fresh broccoli. Nutrition and cancer. 2000;38(2):168-178.

Conklin KA. Cancer Chemotherapy and Antioxidants. The Journal of nutrition. November 1, 2004 2004a;134(11):3201S-3204S.

Conklin KA. Chemotherapy-associated oxidative stress: impact on chemotherapeutic effectiveness. Integr Cancer Ther. 2004b;3(4):294-300.

Conklin KA. Coenzyme q10 for prevention of anthracycline-induced cardiotoxicity. Integrative cancer therapies. Jun 2005;4(2):110-130.

Coriat R, Alexandre J, Nicco C, Quinquis L, Benoit E, Chéreau C, Lemaréchal H, Mir O, Borderie D, Tréluyer JM, Weill B, Coste J, Goldwasser F, Batteux F. Treatment of oxaliplatin-induced peripheral neuropathy by intravenous mangafodipir. J Clin Invest. 2014 Jan 2;124(1):262-72.

Corrie PG, Bulusu R, Wilson CB, Armstrong G, Bond S, Hardy R, Lao-Sirieix S, Parashar D, Ahmad A, Daniel F, Hill M, Wilson G, Blesing C, Moody AM, McAdam K, Osborne M. A randomised study evaluating the use of pyridoxine to avoid capecitabine dose modifications.Br J Cancer. 2012 Aug 7;107(4):585-7.

Cosman R, Brown CS, DeBraganca KC, Khasraw M. Patterns of care in adult medulloblastoma: results of an international online survey. J Neurooncol. 2014;120(1):125-9.

Coutsouvelis J, Wiseman M, Hui L, Poole S, Dooley M, Patil S, Avery S, Wei A, Spencer A. Effectiveness of a single fixed dose of rasburicase 3 mg in the management of tumour lysis syndrome. Br J Clin Pharmacol. 2013 Feb;75(2):550-3.

Crawford J, Dale DC, Lyman GH. Chemotherapy-induced neutropenia: risks, consequences, and new directions for its management. Cancer. Jan 15 2004;100(2):228-237.

Cronin M, Ross JS. Comprehensive next-generation cancer genome sequencing in the era of targeted therapy and personalized oncology. Biomarkers in Medicine. 2011;5(3):293-305.

Cruciani RA, Dvorkin E, Homel P, Malamud S, Culliney B, Lapin J, . . . Esteban-Cruciani N. Safety, tolerability and symptom outcomes associated with L-carnitine supplementation in patients with cancer, fatigue, and carnitine deficiency: a phase I/II study. Journal of pain and symptom management. Dec 2006;32(6):551-559.

Cruciani RA, Zhang JJ, Manola J, Cella D, Ansari B, Fisch MJ. L-carnitine supplementation for the management of fatigue in patients with cancer: an eastern cooperative oncology group phase III, randomized, double-blind, placebo-controlled trial. Journal of clinical oncology: official journal of the American Society of Clinical Oncology. Nov 01 2012;30(31):3864-3869.

CRUK. Cancer Research UK. Why plan chemotherapy. Last updated 1/6/2015. Accessed 3/17/2017.

Dale DC. Optimizing the management of chemotherapy-induced neutropenia. Clinical advances in hematology & oncology: H&O. Nov 2003;1(11):679-684.

Daugan M, Dufay Wojcicki A, d'Hayer B, Boudy V. Metformin: An anti-diabetic drug to fight cancer. Pharmacological research: the official journal of the Italian Pharmacological Society. Nov 2016;113(Pt A):675-685.

Davenport A, Frezza M, Shen M, Ge Y, Huo C, Chan TH, Dou QP. Celastrol and an EGCG pro-drug exhibit potent chemosensitizing activity in human leukemia cells. International journal of molecular medicine. 2010;25(3):465-470.

Davidson W, Teleni L, Muller J, Ferguson M, McCarthy AL, Vick J, Isenring E. Malnutrition and chemotherapy-induced nausea and vomiting: implications for practice. Oncol Nurs Forum. 2012;39(4):E340-5.

Davila M, Bresalier RS. Gastrointestinal complications of oncologic therapy. Nat Clin Pract Gastroenterol Hepatol. 2008 Dec;5(12):682-96.

de Groot S, Vreeswijk MP, Welters MJ, Gravesteijn G, Boei JJ, Jochems A, . . . Kroep JR. The effects of short-term fasting on tolerance to (neo) adjuvant chemotherapy in HER2-negative breast cancer patients: a randomized pilot study. BMC cancer. 2015;15:652.

De Leonardis V, De Scalzi M, Neri B, Bartalucci S, Cinelli P. Echocardiographic assessment of anthracycline cardiotoxicity during different therapeutic regimens. International journal of clinical pharmacology research. 1987;7(4):307-311.

De Los Santos JF, Small W. The role of amifostine in the treatment of carcinoma of the uterine cervix: an update of RTOG-0116 and review of future directions. Semin Oncol. 2004 Dec;31(6 Suppl 18):37-41.

de Oliveira Campos MP, Riechelmann R, Martins LC, Hassan BJ, Casa FB, Del Giglio A. Guarana (Paullinia cupana) improves fatigue in breast cancer patients undergoing systemic chemotherapy. J Altern Complement Med. 2011 Jun;17(6):505-12

De Palma M, Hanahan D. The biology of personalized cancer medicine: facing individual complexities underlying hallmark capabilities. Molecular oncology. Apr 2012;6(2):111-127.

De Vecchis R, Baldi C, Di Biase G, Ariano C, Cioppa C, Giasi A, . . . Cantatrione S. Cardiovascular risk associated with celecoxib or etoricoxib: a meta-analysis of randomized controlled trials which adopted comparison with placebo or naproxen. Minerva cardioangiologica. Dec 2014;62(6):437-448.

DeBoer MD. Emergence of ghrelin as a treatment for cachexia syndromes. Nutrition (Burbank, Los Angeles County, Calif.). Sep 2008;24(9):806-814.

del Giglio AB, Cubero Dde I, Lerner TG, Guariento RT, de Azevedo RG, Paiva H, Goldman C, Carelli B, Cruz FM, Schindler F, Pianowski L, de Matos LL, del Giglio A. Purified dry extract of Paullinia cupana (guaraná) (PC-18) for chemotherapy-related fatigue in patients with solid tumors: an early discontinuation study. J Diet Suppl. 2013 Dec;10(4):325-34.

DeMario MD, Ratain MJ. Oral chemotherapy: rationale and future directions. J Clin Oncol. 1998;16(7):2557-67.

Demidov LV, Manziuk LV, Kharkevitch GY, Pirogova NA, Artamonova EV. Adjuvant fermented wheat germ extract (Avemar™) nutraceutical improves survival of high-risk skin melanoma patients: a randomized, pilot, phase II clinical study with a 7-year follow-up. Cancer biotherapy & radiopharmaceuticals. 2008;23(4):477-482.

Deng PB, Hu CP, Xiong Z, Yang HP, Li YY. Treatment with EGCG in NSCLC leads to decreasing interstitial fluid pressure and hypoxia to improve chemotherapy efficacy through rebalance of Ang-1 and Ang-2. Chin J Nat Med. 2013 May;11(3):245-53.

Dezso Z, Oestreicher J, Weaver A, Santiago S, Agoulnik S, Chow J, . . . Funahashi Y. Gene Expression Profiling Reveals Epithelial Mesenchymal Transition (EMT) Genes Can Selectively Differentiate Eribulin Sensitive Breast Cancer Cells. PloS one. 2014;9(8):e106131.

Dhandapani KM, Mahesh VB, Brann DW. Curcumin suppresses growth and chemoresistance of human glioblastoma cells via AP-1 and NFkappaB transcription factors. Journal of neurochemistry. Jul 2007;102(2):522-538.

Dibble SL, Luce J, Cooper BA, Israel J, Cohen M, Nussey B, Rugo H. Acupressure for chemotherapy-induced nausea and vomiting: a randomized clinical trial. Oncol Nurs Forum. 2007 Jul;34(4):813-20.

Dimitrov V, Salehi-Tabar R, An BS, White JH. Non-classical mechanisms of transcriptional regulation by the vitamin D receptor: Insights into calcium homeostasis, immune system regulation and cancer chemoprevention. The Journal of steroid biochemistry and molecular biology. Oct 2014;144pa:74-80.

Dincol D, Buyukcelik A, Dogan M, Akbulut H, Samur M, Demirkazik A, Senler FC, Onur H, Icli F. Long-term outcome of mesna, ifosfamide, mitoxantrone, etoposide (MINE) regimen as a consolidation in patients with aggressive non-Hodgkin lymphoma responding to CHOP. Med Oncol. 2010 Sep;27(3):942-5.

Dixon RA, Xie DY, Sharma SB. Proanthocyanidins--a final frontier in flavonoid research? The New phytologist. Jan 2005;165(1):9-28.

Dong L, Zhou Q, Zhang Z, Zhu Y, Duan T, Feng Y. Metformin sensitizes endometrial cancer cells to chemotherapy by repressing glyoxalase I expression. J Obstet Gynaecol Res. 2012;38(8):1077-85.

Doroshow JH, Goldman L (ed.), Schafer Ae. Goldman's Cecil Medicine, Twenty-Fifth Edition. Chapter 179: Approach To The Patient With Cancer; 1206-1222e2. Copyright 2017 Saunders, an imprint of Elsevier, Inc. Available at: Accessed 1/11/2017.

Dorr RT. Chemoprotectants for cancer chemotherapy. Seminars in oncology. Feb 1991;18(1 Suppl 2):48-58.

dos Santos NA, Carvalho Rodrigues MA, Martins NM, dos Santos AC. Cisplatin-induced nephrotoxicity and targets of nephroprotection: an update. Archives of toxicology. Aug 2012;86(8):1233-1250.

Drisko JA, Chapman J, Hunter VJ. The use of antioxidant therapies during chemotherapy. Gynecologic oncology. 2003;88(3):434-439.

Duan P, Wang ZM. [Clinical study on effect of Astragalus in efficacy enhancing and toxicity reducing of chemotherapy in patients of malignant tumor]. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2002 Jul;22(7):515-7.

Duffy MJ, Crown J. A personalized approach to cancer treatment: how biomarkers can help. Clin Chem. 2008 Nov;54(11):1770-9.

Dundee JW, Yang J. Prolongation of the antiemetic action of P6 acupuncture by acupressure in patients having cancer chemotherapy. J R Soc Med. Jun 1990;83(6):360-362.

Duval M, Daniel SJ. Meta-analysis of the efficacy of amifostine in the prevention of cisplatin ototoxicity. J Otolaryngol Head Neck Surg. 2012 Oct;41(5):309-15.

Eisenbraun J, Scheer R, Kröz M, Schad F, Huber R. Quality of life in breast cancer patients during chemotherapy and concurrent therapy with a mistletoe extract. Phytomedicine. 2011 Jan 15;18(2-3):151-7.

Ekwall EM, Nygren LM, Gustafsson AO, Sorbe BG. Determination of the most effective cooling temperature for the prevention of chemotherapy-induced alopecia. Molecular and clinical oncology. Nov 2013;1(6):1065-1071.

El-Bakly WM, Louka ML, El-Halawany AM, Schaalan MF. 6-gingerol ameliorated doxorubicin-induced cardiotoxicity: role of nuclear factor kappa B and protein glycation. Cancer chemotherapy and pharmacology. Dec 2012;70(6):833-841.

Elberry AA, Abdel-Naim AB, Abdel-Sattar EA, Nagy AA, Mosli HA, Mohamadin AM, Ashour OM. Cranberry (Vaccinium macrocarpon) protects against doxorubicin-induced cardiotoxicity in rats. Food and chemical toxicology: an international journal published for the British Industrial Biological Research Association. May 2010;48(5):1178-1184.

El-Housseiny AA, Saleh SM, El-Masry AA, Allam AA. The effectiveness of vitamin "E" in the treatment of oral mucositis in children receiving chemotherapy. The Journal of clinical pediatric dentistry. Spring 2007;31(3):167-170.

El-Mowafy AM, Al-Gayyar MM, Salem HA, El-Mesery ME, Darweish MM. Novel chemotherapeutic and renal protective effects for the green tea (EGCG): role of oxidative stress and inflammatory-cytokine signaling. Phytomedicine. 2010 Dec 1;17(14):1067-75.

El-Rayes BF, Shields AF, Vaishampayan U, Heilbrun LK, Zalupski MM, Philip PA. A dose attenuated schedule of irinotecan and capecitabine in combination with celecoxib in advanced colorectal cancer. Journal of clinical oncology: official journal of the American Society of Clinical Oncology. Jun 20 2006;24(18_suppl):3584.

Erhola M, Kellokumpu-Lehtinen P, Metsä-Ketelä T, Alanko K, Nieminen MM. Effects of anthracyclin-based chemotherapy on total plasma antioxidant capacity in small cell lung cancer patients. Free Radical Biology and Medicine. 1996;21(3):383-390.

Esserman L, Berry D, Cheang MU, Yau C, Perou C, Carey L, . . . Hylton N. Chemotherapy response and recurrence-free survival in neoadjuvant breast cancer depends on biomarker profiles: results from the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657). Breast cancer research and treatment. 2012;132(3):1049-1062.

Ethyol. [Package Insert]. Ben Venue, Inc., Bedford, OH. Last updated 6/1999. Accessed 2/22/2017.

Eum S, Choi HD, Chang MJ, Choi HC, Ko YJ, Ahn JS, Shin WG, Lee JY. Protective effects of vitamin E on chemotherapy-induced peripheral neuropathy: a meta-analysis of randomized controlled trials. Int J Vitam Nutr Res. 2013;83(2):101-11.

Eustace AJ, Kennedy S, Larkin AM, Mahgoub T, Tryfonopoulos D, O'Driscoll L, . . . O'Donovan N. Predictive biomarkers for dasatinib treatment in melanoma. Oncoscience. 2014;1(2):158-166.

Fakih MG, Andrews C, McMahon J, Muindi JR. A prospective clinical trial of cholecalciferol 2000 IU/day in colorectal cancer patients: evidence of a chemotherapy-response interaction. Anticancer Res. 2012 Apr;32(4):1333-8.

Falsaperla M, Morgia G, Tartarone A, Ardito R, Romano G. Support ellagic acid therapy in patients with hormone refractory prostate cancer (HRPC) on standard chemotherapy using vinorelbine and estramustine phosphate. Eur Urol. Apr 2005;47(4):449-454; discussion 454-445.

FDA. U.S. Food and Drug Administration website. Drugs page. Ado-Trastuzumab Emtansine. Available at: Last updated 2/25/2013. Accessed 8/7/2014.

Fearon K, Arends J, Baracos V. Understanding the mechanisms and treatment options in cancer cachexia. Nature reviews. Clinical oncology. Feb 2013;10(2):90-99.

Feddock J, Kudrimoti M, Randall M. No cookie-cutter oncology: individualized treatment approaches for women with corpus endometrial cancer. Expert review of anticancer therapy. Jul 2010;10(7):1087-1100.

Feldman D, Krishnan AV, Swami S, Giovannucci E, Feldman BJ. The role of vitamin D in reducing cancer risk and progression. Nat Rev Cancer. May 2014;14(5):342-357.

Feng SS, Zhao L, Tang J. Nanomedicine for oral chemotherapy. Nanomedicine (Lond). 2011;6(3):407-10.

Fisher M, Yang LX. Anticancer effects and mechanisms of polysaccharide-K (PSK): implications of cancer immunotherapy. Anticancer research. May-Jun 2002;22(3):1737-1754.

Fritz H, Kennedy DA, Ishii M, Fergusson D, Fernandes R, Cooley K, Seely D. Polysaccharide K and Coriolus versicolor extracts for lung cancer: a systematic review. Integrative cancer therapies. May 2015;14(3):201-211.

Fuchs-Tarlovsky V, Rivera MA, Altamirano KA, Lopez-Alvarenga JC, Ceballos-Reyes GM. Antioxidant supplementation has a positive effect on oxidative stress and hematological toxicity during oncology treatment in cervical cancer patients. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer. May 2013;21(5):1359-1363.

Fukawa T, Yan-Jiang BC, Min-Wen JC, Jun-Hao ET, Huang D, Qian CN, . . . Shyh-Chang N. Excessive fatty acid oxidation induces muscle atrophy in cancer cachexia. Nat Med. Jun 2016;22(6):666-671.

Fukaya H, Kanno H. [Experimental studies of the protective effect of ginkgo biloba extract (GBE) on cisplatin-induced toxicity in rats]. Nihon Jibiinkoka Gakkai kaiho. Jul 1999;102(7):907-917.

Gallant JN, Matthew EM, Cheng H, Harouaka R, Lamparella NE, Kunkel M, . . . El-Deiry WS. Predicting therapy response in live tumor cells isolated with the flexible micro spring array device. Cell cycle (Georgetown, Tex.). Jul 1 2013;12(13):2132-2143.

Galmarini D, Galmarini CM, Galmarini FC. Cancer chemotherapy: a critical analysis of its 60 years of history. Crit Rev Oncol Hematol. 2012 Nov;84(2):181-99

Gao HF, Liang Y, Zhou NN, Zhang DS, Wu HY. Aprepitant plus palonosetron and dexamethasone for prevention of chemotherapy-induced nausea and vomiting in patients receiving multiple-day cisplatin chemotherapy. Internal medicine journal. Jan 2013;43(1):73-76.

Gao YT, Wu LY, Zhang W, Zhao D, Li N, Tian HM, . . . Li XG. [A prospective study of adenosine triphosphate-tumor chemosensitivity assay directed chemotherapy in patients with recurrent ovarian cancer]. Zhonghua fu chan ke za zhi. May 2013;48(5):358-363.

Gaona-Gaona L, Molina-Jijon E, Tapia E, Zazueta C, Hernandez-Pando R, Calderon-Oliver M, . . . Pedraza-Chaverri J. Protective effect of sulforaphane pretreatment against cisplatin-induced liver and mitochondrial oxidant damage in rats. Toxicology. Aug 15 2011;286(1-3):20-27.

Garami M, Schuler D, Babosa M, Borgulya G, Hauser P, Müller J, . . . Fekete G. Fermented wheat germ extract reduces chemotherapy-induced febrile neutropenia in pediatric cancer patients. Journal of pediatric hematology/oncology. 2004;26(10):631-635.

Garralda E, Paz K, Lopez-Casas PP, Jones S, Katz A, Kann LM, . . . Hidalgo M. Integrated next-generation sequencing and avatar mouse models for personalized cancer treatment. Clinical cancer research: an official journal of the American Association for Cancer Research. May 1 2014;20(9):2476-2484.

Gayathri BN, Rao KS. Pancytopenia: a clinico hematological study. J Lab Physicians. 2011 Jan;3(1):15-20.

Gazzaniga P, Naso G, Gradilone A, Cortesi E, Gandini O, Gianni W, . . . Cristofanilli M. Chemosensitivity profile assay of circulating cancer cells: prognostic and predictive value in epithelial tumors. International journal of cancer. Journal international du cancer. May 15 2010;126(10):2437-2447.

Gedlicka C, Kornek GV, Schmid K, Scheithauer W. Amelioration of docetaxel/cisplatin induced polyneuropathy by α-lipoic acid. Annals of Oncology. 2003;14(2):339-340.

Geng M, Wang L, Li P. Correlation between chemosensitivity to anticancer drugs and Bcl-2 expression in gastric cancer. International journal of clinical and experimental pathology. 2013;6(11):2554-2559.

Gesme DH, Wiseman M. Strategic Use of Clinical Pathways. Journal of oncology practice / American Society of Clinical Oncology. Jan 2011;7(1):54-56.

Gewandter JS, Mohile SG, Heckler CE, Ryan JL, Kirshner JJ, Flynn PJ, Hopkins JO, Morrow GR. A phase III randomized, placebo-controlled study of topical amitriptyline and ketamine for chemotherapy-induced peripheral neuropathy (CIPN): a University of Rochester CCOP study of 462 cancer survivors. Support Care Cancer. 2014 Jul;22(7):1807-14.

Ghalaut VS, Sangwan L, Dahiya K, et al. Effect of imatinib therapy with and without turmeric powder on nitric oxide levels in chronic myeloid leukemia. J Oncol Pharm Pract. 2012;18(2):186-90.

Ghoneum M, Agrawal S. Activation of human monocyte-derived dendritic cells in vitro by the biological response modifier arabinoxylan rice bran (MGN-3/Biobran). International journal of immunopathology and pharmacology. Oct-Dec 2011;24(4):941-948.

Ghoneum M, Badr El-Din NK, Ali DA, El-Dein MA. Modified arabinoxylan from rice bran, MGN-3/biobran, sensitizes metastatic breast cancer cells to paclitaxel in vitro. Anticancer research. Jan 2014;34(1):81-87.

Ghoneum M, Gollapudi S. Modified arabinoxylan rice bran (MGN-3/Biobran) sensitizes human T cell leukemia cells to death receptor (CD95)-induced apoptosis. Cancer letters. Nov 10 2003;201(1):41-49.

Ghoneum M, Matsuura M. Augmentation of macrophage phagocytosis by modified arabinoxylan rice bran (MGN-3/biobran). International journal of immunopathology and pharmacology. Sep-Dec 2004;17(3):283-292.

Ghorbani A, Omidvar B, Parsi A. Protective effect of selenium on cisplatin induced nephrotoxicity: A double-blind controlled randomized clinical trial. J Nephropathol. 2013 Apr;2(2):129-34

Ghorbani A. Renal protective effect of selenium on cisplatin-induced nephrotoxicity. J Ren Inj Prev. 2013;1(1):31-32.

Ghoreishi Z, Esfahani A, Djazayeri A, Djalali M, Golestan B, Ayromlou H, Hashemzade S, Asghari Jafarabadi M, Montazeri V, Keshavarz SA, Darabi M. Omega-3 fatty acids are protective against paclitaxel-induced peripheral neuropathy: a randomized double-blind placebo controlled trial. BMC Cancer. 2012 Aug 15;12:355.

Gibson RJ, Keefe DM. Cancer chemotherapy-induced diarrhoea and constipation: mechanisms of damage and prevention strategies. Support Care Cancer. 2006 Sep;14(9):890-900.

Glaysher S, Cree IA. Cell sensitivity assays: the ATP-based tumor chemosensitivity assay. Methods in molecular biology (Clifton, N.J.). 2011;731:247-257.

Gold Standard. Drug Monograph. Aprepitant, Fosaprepitant. Last updated 2/24/2016a. Accessed 1/13/2017.

Gold Standard. Drug Monograph. Cyclophosphamide. Last updated 2/19/2016b. Accessed 1/13/2017.

Gold Standard. Drug Monograph. Dexrazoxane. Last updated 7/16/2012. Accessed 7/21/2015.

Gold Standard. Drug Monograph. Megestrol. Last updated 3/25/2016c. Accessed 2/20/2017.

Gold Standard. Drug Monograph. Palonosetron. Last updated 9/23/2014. Accessed 1/13/2017.

Goldfarb Y, Shapiro H, Singer P, Kalderon Y, Levi B, Glasner A, . . . Ben-Eliyahu S. Fish oil attenuates surgery-induced immunosuppression, limits post-operative metastatic dissemination and increases long-term recurrence-free survival in rodents inoculated with cancer cells. Clinical nutrition (Edinburgh, Scotland). Jun 2012;31(3):396-404.

Gollapudi S, Ghoneum M. MGN-3/Biobran, modified arabinoxylan from rice bran, sensitizes human breast cancer cells to chemotherapeutic agent, daunorubicin. Cancer detection and prevention. 2008;32(1):1-6.

Goncalves R, Bose R. Using multigene tests to select treatment for early-stage breast cancer. J Natl Compr Canc Netw. 2013 Feb 1;11(2):174-82; quiz 182.

Gralla RJ. Updated CINV Guidelines: New Evidence for Change and Practical Issues. Copyright 2016. Accessed 1/13/2017.

Granci V, Cai F, Lecumberri E, Clerc A, Dupertuis YM, Pichard C. Colon cancer cell chemosensitisation by fish oil emulsion involves apoptotic mitochondria pathway. The British journal of nutrition. Apr 14 2013;109(7):1188-1195.

Graziano F, Bisonni R, Catalano V, Silva R, Rovidati S, Mencarini E, . . . Lai V. Potential role of levocarnitine supplementation for the treatment of chemotherapy-induced fatigue in non-anaemic cancer patients. British journal of cancer. Jun 17 2002;86(12):1854-1857.

Green JM. Glucarpidase to combat toxic levels of methotrexate in patients. Ther Clin Risk Manag. 2012;8:403-13.

Grendys EC, Jr., Fiorica JV, Orr JW, Jr., Holloway R, Wang D, Tian C, . . . Herzog TJ. Overview of a chemoresponse assay in ovarian cancer. Clinical & translational oncology: official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico. Sep 2014;16(9):761-769.

Griggs J, Weiss M. Ask-the-Expert Online Conference: Chemotherapy Updates. 2/2002. Accessed 1/13/2017.

Grigsby PW, Zighelboim I, Powell MA, Mutch DG, Schwarz JK. In vitro chemoresponse to cisplatin and outcomes in cervical cancer. Gynecologic oncology. Jul 2013;130(1):188-191.

Grunberg SM, Slusher B, Rugo HS. Emerging treatments in chemotherapy-induced nausea and vomiting. Clinical advances in hematology & oncology: H&O. Feb 2013;11(2 Suppl 1):1-18; quiz 12 p following 18.

Guan YF, Li GR, Wang RJ, Yi YT, Yang L, Jiang D, . . . Peng Y. Application of next-generation sequencing in clinical oncology to advance personalized treatment of cancer. Chinese journal of cancer. Oct 2012;31(10):463-470.

Gulec M, Iraz M, Yilmaz HR, Ozyurt H, Temel I. The effects of ginkgo biloba extract on tissue adenosine deaminase, xanthine oxidase, myeloperoxidase, malondialdehyde, and nitric oxide in cisplatin-induced nephrotoxicity. Toxicology and industrial health. Apr 2006;22(3):125-130.

Guo L, Bai SP, Zhao L, Wang XH. Astragalus polysaccharide injection integrated with vinorelbine and cisplatin for patients with advanced non-small cell lung cancer: effects on quality of life and survival. Med Oncol. 2012;29(3):1656-62.

Gupta YK, Sharma SS, Rai K, Katiyar CK. Reversal of paclitaxel induced neutropenia by Withania somnifera in mice. Indian J Physiol Pharmacol. 2001 Apr;45(2):253-7.

Gurney JG, Bass JK, Onar-Thomas A, Huang J, Chintagumpala M, Bouffet E, Hassall T, Gururangan S, Heath JA, Kellie S, Cohn R, Fisher MJ, Panandiker AP, Merchant TE, Srinivasan A, Wetmore C, Qaddoumi I, Stewart CF, Armstrong GT, Broniscer A, Gajjar A. Evaluation of amifostine for protection against cisplatin-induced serious hearing loss in children treated for average-risk or high-risk medulloblastoma. Neuro Oncol. 2014 Jun;16(6):848-55.

Gustafson DL, Long ME, Bradshaw EL, Merz AL, Kerzic PJ. P450 induction alters paclitaxel pharmacokinetics and tissue distribution with multiple dosing. Cancer chemotherapy and pharmacology. 2005;56(3):248-254.

Guttuso T Jr. Gabapentin's anti-nausea and anti-emetic effects: a review. Exp Brain Res. 2014;232(8):2535-9.

Haniadka R, Rajeev AG, Palatty PL, Arora R, Baliga MS. Zingiber officinale (ginger) as an anti-emetic in cancer chemotherapy: a review. J Altern Complement Med. 2012 May;18(5):440-4.

Hart J. Data Support Antioxidant Use During Chemotherapy: An Interview with Keith I. Block, MD. Alternative and Complementary Therapies. 2012;18(2):91-97.

Hartmann JT, Knop S, Fels LM, van Vangerow A, Stolte H, Kanz L, Bokemeyer C. The use of reduced doses of amifostine to ameliorate nephrotoxicity of cisplatin/ifosfamide-based chemotherapy in patients with solid tumors. Anti-cancer drugs. Jan 2000;11(1):1-6.

Hasinoff BB, Herman EH. Dexrazoxane: how it works in cardiac and tumor cells. Is it a prodrug or is it a drug? Cardiovasc Toxicol. 2007;7(2):140-4.

Healthwise. Cigna website. Health & Wellness page. Antitumor Antibiotics for Chemotherapy. Available at: Last updated 8/14/2013. Accessed 9/4/2014.

Heijkoop ST, Franckena M, Thomeer MG, Boere IA, Van Montfort C, Van Doorn HC. Neoadjuvant chemotherapy followed by radiotherapy and concurrent hyperthermia in patients with advanced-stage cervical cancer: a retrospective study. International journal of hyperthermia: the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. 2012;28(6):554-561.

Held K, Ryan R, Champion JM, August K, Radhi MA. Caregiver survey results related to handling of oral chemotherapy for pediatric patients with acute lymphoblastic leukemia. Journal of pediatric hematology/oncology. 2013;35(6):e249-253.

Held-Warmkessel J. How to prevent and manage tumor lysis syndrome. Nursing. 2010 Feb;40(2):26-31; quiz 31-2.

Hemati S, Arbab JN, Rafienia M, Ghavamnasiri M. The effects of vitamin E and selenium on cisplatin-induced nephrotoxicity in cancer patients treated with cisplatin-based chemotherapy: A randomized, placebo-controlled study. J Res Med Sci. 2012;17:S49–58.

Hendlisz A, Golfinopoulos V, Deleporte A, Paesmans M, Mansy H, Garcia C, Peeters M, Annemans L, Vandeputte C, Maetens M, Borbath I, Dresse D, Houbier G, Fried M, Awada A, Piccart M, Laethem JL, Flamen P. Preoperative chemosensitivity testing as Predictor of Treatment benefit in Adjuvant stage III colon cancer (PePiTA): Protocol of a prospective BGDO (Belgian Group for Digestive Oncology) multicentric study. BMC Cancer. 2013;13(1):190.

Hendrikx JJ, Lagas JS, Rosing H, Schellens JH, Beijnen JH, Schinkel AH. P-glycoprotein and cytochrome P450 3A act together in restricting the oral bioavailability of paclitaxel.Int J Cancer. 2013;132(10):2439-47.

Hensley ML, Hagerty KL, Kewalramani T, Green DM, Meropol NJ, Wasserman TH, Cohen GI, Emami B, Gradishar WJ, Mitchell RB, Thigpen JT, Trotti A 3rd, von Hoff D, Schuchter LM. American Society of Clinical Oncology 2008 clinical practice guideline update: use of chemotherapy and radiation therapy protectants. J Clin Oncol. 2009 Jan 1;27(1):127-45.

Hernandez SL, Sheyner I, Stover KT, Stewart JT. Dronabinol Treatment of Refractory Nausea and Vomiting Related to Peritoneal Carcinomatosis. Am J Hosp Palliat Care. 2013 Sep 19. [Epub ahead of print].

Herzog TJ, Krivak TC, Fader AN, Coleman RL. Chemosensitivity testing with ChemoFx and overall survival in primary ovarian cancer. American journal of obstetrics and gynecology. Jul 2010;203(1):68.e61-66.

Hess LM, Insel KC. Chemotherapy-related change in cognitive function: a conceptual model. Oncology nursing forum. Sep 2007;34(5):981-994.

Higashiyama M, Okami J, Maeda J, Tokunaga T, Fujiwara A, Kodama K, Imamura F, Kobayashi H. Differences in chemosensitivity between primary and paired metastatic lung cancer tissues: In vitro analysis based on the collagen gel droplet embedded culture drug test (CD-DST). J Thorac Dis. 2012 Feb;4(1):40-7.

Higdon J. OSU: Linus Pauling Institute web page. Isothiocyanates. Available at: Last updated 11/2008. Accessed 9/9/2014.

Hilchie AL, Doucette CD, Pinto DM, Patrzykat A, Douglas S, Hoskin DW. Pleurocidin-family cationic antimicrobial peptides are cytolytic for breast carcinoma cells and prevent growth of tumor xenografts. Breast cancer research: BCR. 2011;13(5):R102.

Hildebrandt B, Wust P, Ahlers O, Dieing A, Sreenivasa G, Kerner T, . . . Riess H. The cellular and molecular basis of hyperthermia. Critical reviews in oncology/hematology. Jul 2002;43(1):33-56.

Hilpert F, Stähle A, Tomé O, Burges A, Rossner D, Späthe K, Heilmann V, Richter B, du Bois A; Arbeitsgemeinschaft Gynäkologische Onkologoie (AGO) Ovarian Cancer Study Group. Neuroprotection with amifostine in the first-line treatment of advanced ovarian cancer with carboplatin/paclitaxel-based chemotherapy—a double-blind, placebo-controlled, randomized phase II study from the Arbeitsgemeinschaft Gynäkologische Onkologoie (AGO) Ovarian Cancer Study Group. Support Care Cancer. 2005 Oct;13(10):797-805.

Hine C, Mitchell JR. Saying no to drugs: fasting protects hematopoietic stem cells from chemotherapy and aging. Cell stem cell. Jun 5 2014;14(6):704-705.

Hirai S, Kaida S, Ito T, Hasebe S, Ueno M, Udagawa H, Hayashi M. [Magnesium premedication prevents Cisplatin-induced nephrotoxicity in patients with esophageal and hypopharyngeal cancer]. Gan to kagaku ryoho. Cancer & chemotherapy. Jun 2013;40(6):743-747.

Hirsch HA, Iliopoulos D, Tsichlis PN, Struhl K. Metformin selectively targets cancer stem cells, and acts together with chemotherapy to block tumor growth and prolong remission. Cancer research. 2009;69(19):7507-7511.

Hocking CM, Kichenadasse G. Olanzapine for chemotherapy-induced nausea and vomiting: a systematic review. Support Care Cancer. 2014 Apr;22(4):1143-51.

Hoffer LJ, Robitaille L, Zakarian R, Melnychuk D, Kavan P, Agulnik J, . . . Miller WH, Jr. High-Dose Intravenous Vitamin C Combined with Cytotoxic Chemotherapy in Patients with Advanced Cancer: A Phase I-II Clinical Trial. PloS one. 2015;10(4):e0120228.

Holmboe L, Andersen AM, Mørkrid L, Slørdal L, Hall KS. High dose methotrexate chemotherapy: pharmacokinetics, folate and toxicity in osteosarcoma patients.Br J Clin Pharmacol. 2012 Jan;73(1):106-14.

Honjo S, Ajani JA, Scott AW, Chen Q, Skinner HD, Stroehlein J, Johnson RL, Song S. Metformin sensitizes chemotherapy by targeting cancer stem cells and the mTOR pathway in esophageal cancer. Int J Oncol. 2014;45(2):567-74.

Honkoop A, Pinedo H. High-dose chemotherapy in the treatment of breast-cancer. International journal of oncology. 1995;6(4):911-918.

Horne BD, Cox JE, Muhlestein JB, Le VT, Butler AR, May HT, . . . Anderson JL. Abstract 13412: 24-Hour Water-Only Fasting Acutely Reduces Trimethylamine N-Oxide: the FEELGOOD Trial. Circulation. November 25, 2014 2014;130(Suppl 2):A13412.

Howells LM, Sale S, Sriramareddy SN, Irving GR, Jones DJ, Ottley CJ, . . . Brown K. Curcumin ameliorates oxaliplatin-induced chemoresistance in HCT116 colorectal cancer cells in vitro and in vivo. International journal of cancer. J international du cancer. Jul 15 2011;129(2):476-486.

Hu YJ, Chen Y, Zhang YQ, Zhou MZ, Song XM, Zhang BZ, Luo L, Xu PM, Zhao YN, Zhao YB, Cheng G. The protective role of selenium on the toxicity of cisplatin-contained chemotherapy regimen in cancer patients. Biol Trace Elem Res. 1997 Mar;56(3):331-41.

Huang JS, Wu CL, Fan CW, Chen WH, Yeh KY, Chang PH. Intravenous glutamine appears to reduce the severity of symptomatic platinum-induced neuropathy: a prospective randomized study. Journal of chemotherapy (Florence, Italy). Aug 2015;27(4):235-240.

Huang JY, Sun Y, Fan QX, Zhang YQ. [Efficacy of Shenyi Capsule combined with gemcitabine plus cisplatin in treatment of advanced esophageal cancer: a randomized controlled trial]. Zhong Xi Yi Jie He Xue Bao. 2009;7(11):1047-51.

Huang L, Cai M, Xie X, Chen Y, Luo X. Uptake enhancement of curcumin encapsulated into phosphatidylcholine-shielding micelles by cancer cells. Journal of biomaterials science. Polymer edition. 2014;25(13):1407-1424.

Huang H, He M, Liu L, Huang L. Vitamin E does not decrease the incidence of chemotherapy-induced peripheral neuropathy: a meta-analysis. Contemp Oncol (Pozn). 2016;20(3):237-241.

Huh JW, Park YA, Lee KY, Sohn SK. Heterogeneity of adenosine triphosphate-based chemotherapy response assay in colorectal cancer--secondary publication. Yonsei medical journal. Oct 31 2009;50(5):697-703.

Hunakova L, Gronesova P, Horvathova E, Chalupa I, Cholujova D, Duraj J, Sedlak J. Modulation of cisplatin sensitivity in human ovarian carcinoma A2780 and SKOV3 cell lines by sulforaphane. Toxicol Lett. 2014 Nov 4;230(3):479-86.

Hur H, Kim NK, Kim HG, Min BS, Lee KY, Shin SJ, . . . Choi SH. Adenosine triphosphate-based chemotherapy response assay-guided chemotherapy in unresectable colorectal liver metastasis. British journal of cancer. Jan 3 2012;106(1):53-60.

Ichikawa Y, Ghanefar M, Bayeva M, Wu R, Khechaduri A, Naga Prasad SV, . . . Ardehali H. Cardiotoxicity of doxorubicin is mediated through mitochondrial iron accumulation. The Journal of clinical investigation. Feb 3 2014;124(2):617-630.

Iida N, Dzutsev A, Stewart CA, Smith L, Bouladoux N, Weingarten RA, . . . Goldszmid RS. Commensal bacteria control cancer response to therapy by modulating the tumor microenvironment. Science (New York, N.Y.). Nov 22 2013;342(6161):967-970.

Ingersoll GL, Wasilewski A, Haller M, Pandya K, Bennett J, He H, Hoffmire C, Berry C. Effect of concord grape juice on chemotherapy-induced nausea and vomiting: results of a pilot study. Oncol Nurs Forum. 2010 Mar;37(2):213-21.

Iop A, Manfredi AM, Bonura S. Fatigue in cancer patients receiving chemotherapy: an analysis of published studies. Ann Oncol. 2004 May;15(5):712-20.

Isenring EA, Teleni L. Nutritional counseling and nutritional supplements: a cornerstone of multidisciplinary cancer care for cachectic patients. Current opinion in supportive and palliative care. Dec 2013;7(4):390-395.

Islambulchilar M, Asvadi I, Sanaat Z, Esfahani A, Sattari M. Effect of taurine on febrile episodes in acute lymphoblastic leukemia. Adv Pharm Bull. Mar 2015;5(1):103-108.

Islambulchilar M, Asvadi I, Sanaat Z, Esfahani A, Sattari M. Taurine attenuates chemotherapy-induced nausea and vomiting in acute lymphoblastic leukemia. Amino acids. Oct 17 2014.

Israel L, Hajji O, Grefft-Alami A, Desmoulins D, Succari M, Cals MJ, . . . Morere JF. [Vitamin A augmentation of the effects of chemotherapy in metastatic breast cancers after menopause. Randomized trial in 100 patients]. Annales de medecine interne. 1985;136(7):551-554.

Ito K, Nakazato H, Koike A, et al.; Study Group of Immunochemotherapy with PSK for Colon Cancer. Long-term effect of 5-fluorouracil enhanced by intermittent administration of polysaccharide K after curative resection of colon cancer. A randomized controlled trial for 7-year follow-up. Int J Colorectal Dis. 2004;19(2):157-64.

Jacot W, Pouderoux S, Thezenas S, Chapelle A, Bleuse JP, Romieu G, Lamy PJ. Increased prevalence of vitamin D insufficiency in patients with breast cancer after neoadjuvant chemotherapy. Breast Cancer Res Treat. 2012 Jul;134(2):709-17.

Jadhav U, Ezhilarasan R, Vaughn SF, Berhow MA, Mohanam S. Iberin induces cell cycle arrest and apoptosis in human neuroblastoma cells. International journal of molecular medicine. Mar 2007;19(3):353-361.

Jafari A, Dashti-Khavidaki S, Khalili H, Lessan-Pezeshki M. Potential nephroprotective effects of l-carnitine against drug-induced nephropathy: a review of literature. Expert opinion on drug safety. Jul 2013;12(4):523-543.

Jahangard-Rafsanjani Z, Gholami K, Hadjibabaie M, Shamshiri AR, Alimoghadam K, Sarayani A, Mojtahedzadeh M, Ostadali-Dehaghi M, Ghavamzadeh A. The efficacy of selenium in prevention of oral mucositis in patients undergoing hematopoietic SCT: a randomized clinical trial. Bone Marrow Transplant. 2013 Jun;48(6):832-6.

Jakab F, Shoenfeld Y, Balogh A, Nichelatti M, Hoffmann A, Kahan Z, . . . Hidvegi M. A medical nutriment has supportive value in the treatment of colorectal cancer. British journal of cancer. Aug 4 2003;89(3):465-469.

Janelsins MC, Tejani MA, Kamen C, Peoples AR, Mustian KM, Morrow GR. Current pharmacotherapy for chemotherapy-induced nausea and vomiting in cancer patients. Expert Opin Pharmacother. 2013 Apr;14(6):757-66.

Jansman FG, Sleijfer DT, de Graaf JC, Coenen JL, Brouwers JR. Management of chemotherapy-induced adverse effects in the treatment of colorectal cancer. Drug safety: an international journal of medical toxicology and drug experience. 2001;24(5):353-367.

Janus N, Thariat J, Boulanger H, Deray G, Launay-Vacher V. Proposal for dosage adjustment and timing of chemotherapy in hemodialyzed patients. Annals of oncology: official journal of the European Society for Medical Oncology / ESMO. Jul 2010;21(7):1395-1403.

Jatoi A, Windschitl HE, Loprinzi CL, Sloan JA, Dakhil SR, Mailliard JA, . . . Christensen B. Dronabinol versus megestrol acetate versus combination therapy for cancer-associated anorexia: a North Central Cancer Treatment Group study. Journal of clinical oncology: official journal of the American Society of Clinical Oncology. Jan 15 2002;20(2):567-573.

Jia L, Zhao Y, Liang XJ. Current evaluation of the millennium phytomedicine- ginseng (II): Collected chemical entities, modern pharmacology, and clinical applications emanated from traditional Chinese medicine. Current medicinal chemistry. 2009;16(22):2924-2942.

Jiralerspong S, Palla SL, Giordano SH, Meric-Bernstam F, Liedtke C, Barnett CM, Hsu L, Hung MC, Hortobagyi GN, Gonzalez-Angulo AM. Metformin and pathologic complete responses to neoadjuvant chemotherapy in diabetic patients with breast cancer. J Clin Oncol. 2009 Jul 10;27(20):3297-302.

Jones RL. Utility of dexrazoxane for the reduction of anthracycline-induced cardiotoxicity. Expert review of cardiovascular therapy. Nov 2008;6(10):1311-1317.

Joo WD, Visintin I, Mor G. Targeted cancer therapy--are the days of systemic chemotherapy numbered? Maturitas. Dec 2013;76(4):308-314.

Jordan K, Behlendorf T, Mueller F, Schmoll HJ. Anthracycline extravasation injuries: management with dexrazoxane. Therapeutics and clinical risk management. Apr 2009;5(2):361-366.

Jordan K, Gralla R, Jahn F, Molassiotis A. International antiemetic guidelines on chemotherapy induced nausea and vomiting (CINV): content and implementation in daily routine practice. European journal of pharmacology. Jan 5 2014;722:197-202.

Junjing Z, Yan Z, Baolu Z. Scavenging effects of dexrazoxane on free radicals. Journal of clinical biochemistry and nutrition. Nov 2010;47(3):238-245.

Kadowaki S, Yamaguchi K. [Chemotherapy-induced stomatitis and diarrhea]. Gan To Kagaku Ryoho. 2011 Nov;38(11):1761-6.

Kalam K, Marwick TH. Role of cardioprotective therapy for prevention of cardiotoxicity with chemotherapy: a systematic review and meta-analysis. Eur J Cancer. 2013 Sep;49(13):2900-9.

Kalia M. Personalized oncology: Recent advances and future challenges. Metabolism. 2013;62(Suppl 1):S11-4.

Kamil N, Kamil S, Ahmed SP, Ashraf R, Khurram M, Ali MO. Toxic effects of multiple anticancer drugs on skin. Pakistan journal of pharmaceutical sciences. Jan 2010;23(1):7-14.

Karimi G, Ramezani M, Tahoonian Z. Cisplatin Nephrotoxicity and Protection by Milk Thistle Extract in Rats. Evid Based Complement Alternat Med. 2005;2(3):383-386.

Katoch O, Kumar A, Adhikari JS, Dwarakanath BS, Agrawala PK. Sulforaphane mitigates genotoxicity induced by radiation and anticancer drugs in human lymphocytes. Mutation research. Dec 12 2013;758(1-2):29-34.

Kelleni MT, Amin EF, Abdelrahman AM. Effect of Metformin and Sitagliptin on Doxorubicin-Induced Cardiotoxicity in Rats: Impact of Oxidative Stress, Inflammation, and Apoptosis. Journal of toxicology. 2015;2015:424813.

Kemp G, Rose P, Lurain J, Berman M, Manetta A, Roullet B, Homesley H, Belpomme D, Glick J. Amifostine pretreatment for protection against cyclophosphamide-induced and cisplatin-induced toxicities: results of a randomized control trial in patients with advanced ovarian cancer. J Clin Oncol. 1996 Jul;14(7):2101-12.

Kerbel RS, Kamen BA. The anti-angiogenic basis of metronomic chemotherapy. Nature reviews. Cancer. Jun 2004;4(6):423-436.

Kesler S, Janelsins M, Koovakkattu D, Palesh O, Mustian K, Morrow G, Dhabhar FS. Reduced hippocampal volume and verbal memory performance associated with interleukin-6 and tumor necrosis factor-alpha levels in chemotherapy-treated breast cancer survivors. Brain, behavior, and immunity. Mar 2013;30 Suppl:S109-116.

Keyomarsi K, Pardee AB. Selective protection of normal proliferating cells against the toxic effects of chemotherapeutic agents. Progress in cell cycle research. 2003;5:527-532.

Khan G, Haque SE, Anwer T, Ahsan MN, Safhi MM, Alam MF. Cardioprotective effect of green tea extract on doxorubicin-induced cardiotoxicity in rats. Acta poloniae pharmaceutica. Sep-Oct 2014;71(5):861-868.

Kidd PM. The use of mushroom glucans and proteoglycans in cancer treatment. Alternative medicine review : a journal of clinical therapeutic. Feb 2000;5(1):4-27.

Kim DG, Jung KH, Lee DG, Yoon JH, Choi KS, Kwon SW, Shen HM, Morgan MJ, Hong SS, Kim YS. 20(S)-Ginsenoside Rg3 is a novel inhibitor of autophagy and sensitizes hepatocellular carcinoma to doxorubicin. Oncotarget. 2014;5(12):4438-51.

Kim KC, Yook JH, Eisenbraun J, Kim BS, Huber R. Quality of life, immunomodulation and safety of adjuvant mistletoe treatment in patients with gastric carcinoma – a randomized, controlled pilot study. BMC Complement Altern Med. 2012;12:172.

Kim TH, Shin YJ, Won AJ, Lee BM, Choi WS, Jung JH, Chung HY, Kim HS. Resveratrol enhances chemosensitivity of doxorubicin in multidrug-resistant human breast cancer cells via increased cellular influx of doxorubicin. Biochim Biophys Acta. 2014;1840(1):615-25.

Kirakosyan A, Seymour E, Kaufman PB, Warber S, Bolling S, Chang SC. Antioxidant capacity of polyphenolic extracts from leaves of Crataegus laevigata and Crataegus monogyna (Hawthorn) subjected to drought and cold stress. Journal of agricultural and food chemistry. Jul 02 2003;51(14):3973-3976.

Kissei Pharmaceuticals. Press Release. Announcment of the launch of "SAVENE® Injectable 500 mg" for the Treatment of Anthracycline Extravasation in Japan." Available at: 4/17/2014. Accessed 10/27/2014.

Kitazono S, Takiguchi Y, Ashinuma H, Saito-Kitazono M, Kitamura A, Chiba T, Sakaida E, Sekine I, Tada Y, Kurosu K, Sakao S, Tanabe N, Iwama A, Yokosuka O, Tatsumi K. Effect of metformin on residual cells after chemotherapy in a human lung adenocarcinoma cell line. Int J Oncol. 2013;43(6):1846-54.

Klein ME, Dabbs DJ, Shuai Y, Brufsky AM, Jankowitz R, Puhalla SL, Bhargava R. Prediction of the Oncotype DX recurrence score: use of pathology-generated equations derived by linear regression analysis. Modern pathology: an official journal of the United States and Canadian Academy of Pathology, Inc. May 2013;26(5):658-664.

Kolak A, Staroslawska E, Kubiatowski T, Kieszko D, Cisek P, Patyra KI, . . . Burdan F. [Chemotherapy induced peripheral neuropathy]. Polski merkuriusz lekarski: organ Polskiego Towarzystwa Lekarskiego. Nov 2013;35(209):292-296.

Komaki R, Lee JS, Kaplan B, Allen P, Kelly JF, Liao Z, Stevens CW, Fossella FV, Zinner R, Papadimitrakopoulou V, Khuri F, Glisson B, Pisters K, Kurie J, Herbst R, Milas L, Ro J, Thames HD, Hong WK, Cox JD. Randomized phase III study of chemoradiation with or without amifostine for patients with favorable performance status inoperable stage II-III non-small cell lung cancer: preliminary results. Semin Radiat Oncol. 2002 Jan;12(1 Suppl 1):46-9.

Komen MM, Smorenburg CH, van den Hurk CJ, Nortier JW. [Scalp cooling for chemotherapy-induced alopecia]. Ned Tijdschr Geneeskd. 2011;155(45):A3768.

Kondo T, Sakamoto J, Nakazato H. Alternating immunochemotherapy of advanced gastric carcinoma: a randomized comparison of carbazilquinone and PSK to carbazilquinone in patients with curative gastric resection. Biotherapy. 1991;3(4):287-95.

Kosuge T, Kiuchi T, Mukai K, Kakizoe T. A multicenter randomized controlled trial to evaluate the effect of adjuvant cisplatin and 5-fluorouracil therapy after curative resection in cases of pancreatic cancer. Japanese journal of clinical oncology. Mar 2006;36(3):159-165.

Kraft M, Kraft K, Gartner S, Mayerle J, Simon P, Weber E, . . . Lerch MM. L-Carnitine-supplementation in advanced pancreatic cancer (CARPAN)--a randomized multicentre trial. Nutrition journal. 2012;11:52.

Krop IE, Kim SB, González-Martín A, LoRusso PM, Ferrero JM, Smitt M, Yu R, Leung AC, Wildiers H; TH3RESA study collaborators. Trastuzumab emtansine versus treatment of physician's choice for pretreated HER2-positive advanced breast cancer (TH3RESA): a randomised, open-label, phase 3 trial. Lancet Oncol. 2014 Jun;15(7):689-99.

Krzemieniecki K, Sevelda P, Erdkamp F, Smakal M, Schwenkglenks M, Puertas J, . . . Maenpaa J. Neutropenia management and granulocyte colony-stimulating factor use in patients with solid tumours receiving myelotoxic chemotherapy--findings from clinical practice. Supportive care in cancer: official journal of the Multinational Association of Supportive Care in Cancer. Mar 2014;22(3):667-677.

Kuhn KS, Muscaritoli M, Wischmeyer P, Stehle P. Glutamine as indispensable nutrient in oncology: experimental and clinical evidence. European journal of nutrition. Jun 2010;49(4):197-210.

Lacey JM, Wilmore DW. Is glutamine a conditionally essential amino acid? Nutrition reviews. Aug 1990;48(8):297-309.

Lam MP, Yeung CK, Cheung BM. Pharmacogenetics of allopurinol--making an old drug safer. J Clin Pharmacol. 2013 Jul;53(7):675-9.

Lang M, Henson R, Braconi C, Patel T. Epigallocatechin-gallate modulates chemotherapy-induced apoptosis in human cholangiocarcinoma cells. Liver Int. 2009 May;29(5):670-7.

Laviano A, Rianda S, Molfino A, Rossi Fanelli F. Omega-3 fatty acids in cancer. Current opinion in clinical nutrition and metabolic care. Mar 2013;16(2):156-161.

Lawenda BD, Kelly KM, Ladas EJ, Sagar SM, Vickers A, Blumberg JB. Should supplemental antioxidant administration be avoided during chemotherapy and radiation therapy? Journal of the National Cancer Institute. Jun 4 2008;100(11):773-783.

Lawrence YR, Paulus R, Langer C, Werner-Wasik M, Buyyounouski MK, Komaki R, Machtay M, Smith C, Axelrod RS, Wasserman T, Bradley JD, Movsas B. The addition of amifostine to carboplatin and paclitaxel based chemoradiation in locally advanced non-small cell lung cancer: long-term follow-up of Radiation Therapy Oncology Group (RTOG) randomized trial 9801. Lung Cancer. 2013 Jun;80(3):298-305.

Lederle FA. Epidemiology of constipation in elderly patients. Drug utilisation and cost-containment strategies. Drugs Aging. 1995 Jun;6(6):465-9.

Lee C, Longo VD. Fasting vs dietary restriction in cellular protection and cancer treatment: from model organisms to patients. Oncogene. 2011;30(30):3305-3316.

Lee C, Raffaghello L, Brandhorst S, Safdie FM, Bianchi G, Martin-Montalvo A, . . . Longo VD. Fasting cycles retard growth of tumors and sensitize a range of cancer cell types to chemotherapy. Sci Transl Med. 2012;4(124):124ra127.

Lee C, Safdie FM, Raffaghello L, Wei M, Madia F, Parrella E, . . . Longo VD. Reduced levels of IGF-I mediate differential protection of normal and cancer cells in response to fasting and improve chemotherapeutic index. Cancer research. 2010;70(4):1564-1572.

Lee DJ, Kim B, Lee JH, Park SJ, Hong SP, Cheon JH, Kim TI, Kim WH. [The effect of metformin on responses to chemotherapy and survival in stage IV colorectal cancer with diabetes]. Korean J Gastroenterol. 2012;60(6):355-61.

Lee J, Oh H. Ginger as an antiemetic modality for chemotherapy-induced nausea and vomiting: a systematic review and meta-analysis. Oncol Nurs Forum. 2013;40(2):163-70.

Lenihan DJ, Cardinale DM. Late cardiac effects of cancer treatment. J Clin Oncol. 2012 Oct 20;30(30):3657-64.

Levenga TH, Timmer-Bonte JN. Review of the value of colony stimulating factors for prophylaxis of febrile neutropenic episodes in adult patients treated for haematological malignancies. British journal of haematology. Jul 2007;138(2):146-152.

Li J, Liu H, Ramachandran S, Waypa GB, Yin JJ, Li CQ, . . . Shao ZH. Grape seed proanthocyanidins ameliorate Doxorubicin-induced cardiotoxicity. The American journal of Chinese medicine. 2010;38(3):569-584.

Li RJ, Qiu SD, Chen HX, Wang LR. [Immunomodulatory effects of Astragalus polysaccharide in diabetic mice]. Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine. Feb 2008;6(2):166-170.

Li W, Nie S, Xie M, Chen Y, Li C, Zhang H. A major green tea component, (-)-epigallocatechin-3-gallate, ameliorates doxorubicin-mediated cardiotoxicity in cardiomyocytes of neonatal rats. Journal of agricultural and food chemistry. Aug 25 2010;58(16):8977-8982.

Li Y, Ahmed F, Ali S, Philip PA, Kucuk O, Sarkar FH. Inactivation of nuclear factor kappaB by soy isoflavone genistein contributes to increased apoptosis induced by chemotherapeutic agents in human cancer cells. Cancer Res. 2005 Aug 1;65(15):6934-42.

Li Y, Ellis KL, Ali S, El-Rayes BF, Nedeljkovic-Kurepa A, Kucuk O, Philip PA, Sarkar FH. Apoptosis-inducing effect of chemotherapeutic agents is potentiated by soy isoflavone genistein, a natural inhibitor of NF-kappaB in BxPC-3 pancreatic cancer cell line. Pancreas. 2004 May;28(4):e90-5.

Li Y, Zhang T, Korkaya H, Liu S, Lee HF, Newman B, . . . Sun D. Sulforaphane, a dietary component of broccoli/broccoli sprouts, inhibits breast cancer stem cells. Clinical cancer research: an official journal of the American Association for Cancer Research. May 1 2010;16(9):2580-2590.

Lien K, Georgsdottir S, Sivanathan L, Chan K, Emmenegger U. Low-dose metronomic chemotherapy: a systematic literature analysis. European journal of cancer (Oxford, England: 1990). 2013;49(16):3387-3395.

Liggins J, Bluck LJ, Runswick S, Atkinson C, Coward WA, Bingham SA. Daidzein and genistein content of fruits and nuts. The Journal of nutritional biochemistry. Jun 2000;11(6):326-331.

Lin CM, Abcouwer SF, Souba WW. Effect of dietary glutamate on chemotherapy-induced immunosuppression. Nutrition (Burbank, Los Angeles County, Calif.). Sep 1999;15(9):687-696.

Lin PC, Lee MY, Wang WS, Yen CC, Chao TC, Hsiao LT, Yang MH, Chen PM, Lin KP, Chiou TJ. N-acetylcysteine has neuroprotective effects against oxaliplatin-based adjuvant chemotherapy in colon cancer patients: preliminary data. Support Care Cancer. 2006 May;14(5):484-7.

Lissoni P, Barni S, Fossati V, et al. A randomized study of neuroimmunotherapy with low-dose subcutaneous interleukin-2 plus melatonin compared to supportive care alone in patients with untreatable metastatic solid tumour. Support Care Cancer. 1995;3(3):194-7.

Lissoni P, Barni S, Mandalà M, et al. Decreased toxicity and increased efficacy of cancer chemotherapy using the pineal hormone melatonin in metastatic solid tumour patients with poor clinical status. Eur J Cancer. 1999;35(12):1688-92.

Lissoni P, Barni S, Tancini G, et al. A randomised study with subcutaneous low-dose interleukin 2 alone vs interleukin 2 plus the pineal neurohormone melatonin in advanced solid neoplasms other than renal cancer and melanoma. Br J Cancer. 1994;69(1):196-9.

Lissoni P, Chilelli M, Villa S, Cerizza L, Tancini G. Five years survival in metastatic non-small cell lung cancer patients treated with chemotherapy alone or chemotherapy and melatonin: a randomized trial. J Pineal Res. 2003;35(1):12-5.

Lissoni P, Galli MA, Tancini G, Barni S. Prevention by L-carnitine of interleukin-2 related cardiac toxicity during cancer immunotherapy. Tumori. Jun 30 1993;79(3):202-204.

Lissoni P, Meregalli S, Fossati V, et al. A randomized study of immunotherapy with low-dose subcutaneous interleukin-2 plus melatonin vs chemotherapy with cisplatin and etoposide as first-line therapy for advanced non-small cell lung cancer. Tumori. 1994;80(6):464-7.

Lissoni P, Palorossi F, Ardizzoia A, et al. A randomized study of chemotherapy with cisplatin plus etoposide versus chemoendocrine therapy with cisplatin, etoposide and the pineal hormone melatonin as a first-line treatment of advanced non-small cell lung cancer patients in a poor clinical state. J Pineal Res. 1997;23(1):15-19.

Lissoni P. Biochemotherapy with standard chemotherapies plus the pineal hormone melatonin in the treatment of advanced solid neoplasms. Pathol Biol (Paris). 2007;55(3-4):201-4.

Liu L, Shi R, Shi Q, Cheng Y, Huo Y. Protective effect of saponins from Panax notoginseng against doxorubicin-induced cardiotoxicity in mice. Planta medica. Feb 2008;74(3):203-209.

Liu Y, Li BH, Sun XM, Lin AH, Wang DB. Effect of selenium on the interaction between daunorubicin and cardiac myosin. Biological trace element research. Jun 2012;147(1-3):240-245.

Lyman GH, Dale DC, Culakova E, Poniewierski MS, Wolff DA, Kuderer NM, . . . Crawford J. The impact of the granulocyte colony-stimulating factor on chemotherapy dose intensity and cancer survival: a systematic review and meta-analysis of randomized controlled trials. Annals of oncology: official journal of the European Society for Medical Oncology / ESMO. Oct 2013;24(10):2475-2484.

Lyman GH. Impact of chemotherapy dose intensity on cancer patient outcomes. J Natl Compr Canc Netw. 2009 Jan;7(1):99-108.

Lyman GH. Weight-based chemotherapy dosing in obese patients with cancer: back to the future. J Oncol Pract. 2012 Jul;8(4):e62-4.

Ma Y, Chapman J, Levine M, Polireddy K, Drisko J, Chen Q. High-dose parenteral ascorbate enhanced chemosensitivity of ovarian cancer and reduced toxicity of chemotherapy. Sci Transl Med. 2014;6(222):222ra18.

Ma Y, Trump DL, Johnson CS. Vitamin D in combination cancer treatment. Journal of Cancer. 2010;1:101-107.

Macedo LT, Lima JP, dos Santos LV, Sasse AD. Prevention strategies for chemotherapy-induced hand-foot syndrome: a systematic review and meta-analysis of prospective randomised trials. Support Care Cancer. 2014 Jun;22(6):1585-93.

Machon C, Thezenas S, Dupuy AM, Assenat E, Michel F, Mas E, . . . Cristol JP. Immunonutrition before and during radiochemotherapy: improvement of inflammatory parameters in head and neck cancer patients. Supportive care in cancer: official journal of the Multinational Association of Supportive Care in Cancer. Dec 2012;20(12):3129-3135.

Maciejczyk A, Surowiak P. Quercetin inhibits proliferation and increases sensitivity of ovarian cancer cells to cisplatin and paclitaxel. Ginekologia polska. Jul 2013;84(7):590-595.

Maehara Y, Tsujitani S, Saeki H, Oki E, Yoshinaga K, Emi Y, . . . Baba H. Biological mechanism and clinical effect of protein-bound polysaccharide K (KRESTIN((R))): review of development and future perspectives. Surgery today. Jan 2012;42(1):8-28.

Maestri A, De Pasquale Ceratti A, Cundari S, Zanna C, Cortesi E, Crino L. A pilot study on the effect of acetyl-L-carnitine in paclitaxel- and cisplatin-induced peripheral neuropathy. Tumori. Mar-Apr 2005;91(2):135-138.

Mahoney SE, Davis JM, Murphy EA, McClellan JL, Pena MM. Dietary Quercetin Reduces Chemotherapy-Induced Fatigue in Mice. Integr Cancer Ther. 2014 Sep;13(5):417-24.

Maiti R. Metronomic chemotherapy. Journal of pharmacology & pharmacotherapeutics. 2014;5(3):186-192.

Majithia N, Loprinzi CL, Smith TJ. New Practical Approaches to Chemotherapy-Induced Neuropathic Pain: Prevention, Assessment, and Treatment. Oncology (Williston Park, N.Y.). Nov 15 2016;30(11).

Manikandan R, Kumar S, Dorairajan LN. Hemorrhagic cystitis: A challenge to the urologist. Indian journal of urology: IJU: journal of the Urological Society of India. Apr 2010;26(2):159-166.

Mansky PJ, Wallerstedt DB, Sannes TS, Stagl J, Johnson LL, Blackman MR, . . . Monahan BP. NCCAM/NCI Phase 1 Study of Mistletoe Extract and Gemcitabine in Patients with Advanced Solid Tumors. Evidence-based complementary and alternative medicine: eCAM. 2013;2013:964592.

Marin JJ, Sanchez de Medina F, Castano B, Bujanda L, Romero MR, Martinez-Augustin O, . . . Briz O. Chemoprevention, chemotherapy, and chemoresistance in colorectal cancer. Drug metabolism reviews. May 2012;44(2):148-172.

Maroun JA, Anthony LB, Wong R. Prevention and management of chemotherapy-induced diarrhea in patients with colorectal cancer: a consensus statement by the Canadian Working Group on Chemotherapy-Induced Diarhea. Curr Oncol. 2007;14(1):13-20.

Martinez-Rivera M, Siddik ZH. Resistance and gain-of-resistance phenotypes in cancers harboring wild-type p53. Biochem Pharmacol. 2012;83(8):1049-62.

Martins SP, Ferreira CL, Del Giglio A. Placebo-Controlled, Double-Blind, Randomized Study of a Dry Guarana Extract in Patients with Head and Neck Tumors Undergoing Chemoradiotherapy: Effects on Fatigue and Quality of Life. Journal of dietary supplements. Jun 20 2016:1-10.

Marx W, Kiss N, McCarthy AL, McKavanagh D, Isenring L. Chemotherapy-Induced Nausea and Vomiting: A Narrative Review to Inform Dietetics Practice. Journal of the Academy of Nutrition and Dietetics. May 2016;116(5):819-827.

Marzatico F, Porta C, Moroni M, Bertorelli L, Borasio E, Finotti N, Pansarasa O, Castagna L. In vitro antioxidant properties of amifostine (WR-2721, Ethyol). Cancer Chemother Pharmacol. 2000;45(2):172-6.

Mashiach E, Sela S, Weinstein T, Cohen HI, Shasha SM, Kristal B. Mesna: a novel renoprotective antioxidant in ischaemic acute renal failure. Nephrol Dial Transplant. 2001 Mar;16(3):542-51.

Matera MG, Calzetta L, Cazzola M. Oxidation pathway and exacerbations in COPD: the role of NAC. Expert review of respiratory medicine. 2016;10(1):89-97.

Mattes-Kulig DA, Henkin RI. Energy and nutrient consumption of patients with dysgeusia. Journal of the American Dietetic Association. Jul 1985;85(7):822-826.

Mavroudi M, Zarogoulidis P, Porpodis K, Kioumis I, Lampaki S, Yarmus L, . . . Malecki M. Stem cells' guided gene therapy of cancer: New frontier in personalized and targeted therapy. Journal of cancer research & therapy. 2014;2(1):22-33.

May MB, Glode AE. Dronabinol for chemotherapy-induced nausea and vomiting unresponsive to antiemetics. Cancer management and research. 2016;8:49-55.

Mayo Clinic. Diseases and conditions: Cancer: How to manage hand-foot syndrome. Available at Last updated 04/20/2013. Accessed 12/17/2016.

Mayo Clinic. Tests and Procedures. Chemotherapy. Definition. Available at: Copyright 2015. Accessed 1/7/2015.

McCulloch M, See C, Shu XJ, Broffman M, Kramer A, Fan WY, Gao J, Lieb W, Shieh K, Colford JM Jr. Astragalus-based Chinese herbs and platinum-based chemotherapy for advanced non-small-cell lung cancer: meta-analysis of randomized trials. J Clin Oncol. 2006 Jan 20;24(3):419-430.

McDermott U, Settleman J. Personalized cancer therapy with selective kinase inhibitors: an emerging paradigm in medical oncology. Journal of clinical oncology: official journal of the American Society of Clinical Oncology. Nov 20 2009;27(33):5650-5659.

Mehta MP. Protection of normal tissues from the cytotoxic effects of radiation therapy: focus on amifostine. Semin Radiat Oncol. 1998 Oct;8(4 Suppl 1):14-6.

Melli G, Taiana M, Camozzi F, Triolo D, Podini P, Quattrini A, Taroni F, Lauria G. Alpha-lipoic acid prevents mitochondrial damage and neurotoxicity in experimental chemotherapy neuropathy. Exp Neurol. 2008 Dec;214(2):276-84.

Meric-Bernstam F, Mills GB. Overcoming implementation challenges of personalized cancer therapy. Nature Reviews Clinical Oncology. 2012;9(9):542-548.

Merzoug S, Toumi ML, Tahraoui A. Quercetin mitigates Adriamycin-induced anxiety- and depression-like behaviors, immune dysfunction, and brain oxidative stress in rats. Naunyn Schmiedebergs Arch Pharmacol. 2014 Oct;387(10):921-33.

Meyer F, Bairati I, Fortin A, Gelinas M, Nabid A, Brochet F, Tetu B. Interaction between antioxidant vitamin supplementation and cigarette smoking during radiation therapy in relation to long-term effects on recurrence and mortality: a randomized trial among head and neck cancer patients. International journal of cancer. Apr 01 2008;122(7):1679-1683.

Meyskens FL, Jr., Kopecky KJ, Appelbaum FR, Balcerzak SP, Samlowski W, Hynes H. Effects of vitamin A on survival in patients with chronic myelogenous leukemia: a SWOG randomized trial. Leukemia research. Sep 1995;19(9):605-612.

Michalak K, Wesolowska O. Polyphenols counteract tumor cell chemoresistance conferred by multidrug resistance proteins. Anti-cancer agents in medicinal chemistry. 2012;12(8):880-890.

Michalski CW, Erkan M, Sauliunaite D, Giese T, Stratmann R, Sartori C, . . . Kleeff J. Ex vivo chemosensitivity testing and gene expression profiling predict response towards adjuvant gemcitabine treatment in pancreatic cancer. British journal of cancer. Sep 2 2008;99(5):760-767.

Mihlon F 4th, Ray CE Jr, Messersmith W. Chemotherapy agents: a primer for the interventional radiologist. Semin Intervent Radiol. 2010 Dec;27(4):384-90.

Millenium Pharmaceuticals, Inc. Velcade (bortezomib) [package insert]. Cambridge, MA; 2014.

Miller RP, Tadagavadi RK, Ramesh G, Reeves WB. Mechanisms of Cisplatin Nephrotoxicity. Toxins. 2010;2(11):2490-2518.

Minobe S, Todo Y, Suzuki Y, Aoyagi Y, Umazume T, Okamoto K, Kato H. Mesna, doxorubicin, ifosfamide and dacarbazine chemotherapy for uterine leiomyosarcoma: a report of 2 cases. J Obstet Gynaecol Res. 2011 Jun;37(6):645-9.

Mishra SI, Scherer RW, Snyder C, Geigle PM, Berlanstein DR, Topaloglu O. Exercise interventions on health-related quality of life for people with cancer during active treatment. The Cochrane database of systematic reviews. 2012;8:Cd008465.

Mitchell SA, Hoffman AJ, Clark JC, DeGennaro RM, Poirier P, Robinson CB, Weisbrod BL. Putting evidence into practice: an update of evidence-based interventions for cancer-related fatigue during and following treatment. Clinical journal of oncology nursing. Dec 2014;18 Suppl:38-58.

Mitchell TM. Correspondence re: Somasundaram et al., Dietary Curcumin Inhibits Chemotherapy-induced Apoptosis in Models of Human Breast Cancer. Cancer Res., 62: 3868–3875, 2002. Cancer research. 2003;63(16):5165-5167.

Mitchison TJ. The proliferation rate paradox in antimitotic chemotherapy. Molecular Biology of the Cell. 2012;23(1):1-6.

Mitomi T, Tsuchiya S, Iijima N, et al. Randomized, controlled study on adjuvant immunochemotherapy with PSK in curatively resected colorectal cancer. The Cooperative Study Group of SurgicalAdjuvant Immunochemotherapy for Cancer of Colon and Rectum (Kanagawa). Dis Colon Rectum. 1992;35(2):123-30.

Mitomi T, Tsuchiya S, Iijima N, et al. [Randomized controlled study on adjuvant immunochemotherapy with PSK in curatively resected colorectal cancer. The Cooperative Study Group of Surgical Adjuvant Immunochemotherapy for Cancer of Colon and Rectum]. Gan To Kagaku Ryoho. 1989;16(6):2241-9.

Mohammad RM, Al-Katib A, Aboukameel A, Doerge DR, Sarkar F, Kucuk O. Genistein sensitizes diffuse large cell lymphoma to CHOP (cyclophosphamide, doxorubicin, vincristine, prednisone) chemotherapy. Mol Cancer Ther. 2003 Dec;2(12):1361-8.

Moison RM, Beijersbergen Van Henegouwen GM. Dietary eicosapentaenoic acid prevents systemic immunosuppression in mice induced by UVB radiation. Radiation research. Jul 2001;156(1):36-44.

Molina-Garrido MJ, Mora-Rufete A, Guillen-Ponce C. Oral chemotherapy in elderly women with metastatic breast cancer. Anticancer Agents Med Chem. 2014;14(5):665-72.

Molinaro M, Ameri P, Marone G, Petretta M, Abete P, Di Lisa F, . . . Tocchetti CG. Recent Advances on Pathophysiology, Diagnostic and Therapeutic Insights in Cardiac Dysfunction Induced by Antineoplastic Drugs. BioMed research international. 2015;2015:138148.

Mondul AM, Sampson JN, Moore SC, Weinstein SJ, Evans AM, Karoly ED, . . . Albanes D. Metabolomic profile of response to supplementation with beta-carotene in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study. The American journal of clinical nutrition. Aug 2013;98(2):488-493.

Montazeri AS, Raei M, Ghanbari A, Dadgari A, Montazeri AS, Hamidzadeh A. Effect of herbal therapy to intensity chemotherapy-induced nausea and vomiting in cancer patients. Iranian Red Crescent medical journal. Feb 2013;15(2):101-106.

Morgan G, Ward R, Barton M. The contribution of cytotoxic chemotherapy to 5-year survival in adult malignancies. Clin Oncol (R Coll Radiol). 2004 Dec;16(8):549-60.

Moslehi A, Taghizadeh-Ghehi M, Gholami K, Hadjibabaie M, Jahangard-Rafsanjani Z, Sarayani A, Javadi M, Esfandbod M, Ghavamzadeh A. N-acetyl cysteine for prevention of oral mucositis in hematopoietic SCT: a double-blind, randomized, placebo-controlled trial. Bone Marrow Transplant. 2014 Jun;49(6):818-23.

Moss RW. Should patients undergoing chemotherapy and radiotherapy be prescribed antioxidants? Integrative cancer therapies. Mar 2006;5(1):63-82.

Moukayed M, Grant WB. Molecular link between vitamin D and cancer prevention. Nutrients. Oct 2013;5(10):3993-4021.

Mouser CL, Antoniou ES, Tadros J, Vassiliou EK. A model of hematopoietic stem cell proliferation under the influence of a chemotherapeutic agent in combination with a hematopoietic inducing agent. Theoretical biology & medical modelling. 2014;11:4.

Moynihan TJ. Mayo Clinic. Tests and Procedures. Chemotherapy. Expert Answers page. Available at: 12/10/2014. Accessed 1/16/2015.

Mross K, Steinbild S. Metronomic anti-cancer therapy – an ongoing treatment option for advanced cancer patients. journal of Cancer Therapeutics and Research. 2012 2012;1(1).

Mughal T. ePocrates online. Tumor Lysis Syndrome. Last updated 5/8/2014. Accessed 1/13/2015. Available at:

Mughal TI, Ejaz AA, Foringer JR, Coiffier B. An integrated clinical approach for the identification, prevention, and treatment of tumor lysis syndrome. Cancer Treat Rev. 2010 Apr;36(2):164-76.

Muraki K, Koyama R, Honma Y, Yagishita S, Shukuya T, Ohashi R, . . . Takahashi K. Hydration with magnesium and mannitol without furosemide prevents the nephrotoxicity induced by cisplatin and pemetrexed in patients with advanced non-small cell lung cancer. Journal of thoracic disease. Dec 2012;4(6):562-568.

Murphy RA, Mourtzakis M, Chu QS, Baracos VE, Reiman T, Mazurak VC. Supplementation with fish oil increases first-line chemotherapy efficacy in patients with advanced nonsmall cell lung cancer. Cancer. 2011;117(16):3774-3780.

Murphy RA, Mourtzakis M, Mazurak VC. n-3 polyunsaturated fatty acids: the potential role for supplementation in cancer. Current opinion in clinical nutrition and metabolic care. May 2012;15(3):246-251.

Muthuramalingam S, Gale J, Bradbury J. Dexrazoxane efficacy for anthracycline extravasation: use in UK clinical practice. International journal of clinical practice. Mar 2013;67(3):244-249.

Naglik JR, Challacombe SJ, Hube B. Candida albicans secreted aspartyl proteinases in virulence and pathogenesis. Microbiology and molecular biology reviews: MMBR. Sep 2003;67(3):400-428, table of contents.

Nakamura R, Saikawa Y, Kubota T, Kumagai A, Kiyota T, Ohashi M, Yoshida M, Otani Y, Kumai K, Kitajima M. Role of the MTT chemosensitivity test in the prognosis of gastric cancer patients after postoperative adjuvant chemotherapy. Anticancer Res. 2006 Mar-Apr;26(2B):1433-7.

Nakayama A, Alladin KP, Igbokwe O, White JD. Systematic review: generating evidence-based guidelines on the concurrent use of dietary antioxidants and chemotherapy or radiotherapy. Cancer Invest. 2011 Dec;29(10):655-67.

Nakazato H, Koike A, Ichihashi H, et al. [An effect of adjuvant immunochemotherapy using krestin and 5-FU on gastric cancer patients with radical surgery (first report)--a randomized controlled trial by the cooperative study group. Study Group of Immuno-chemotherapy with PSK for Gastric Cancer]. Gan To Kagaku Ryoho. 1989;16(8 Pt 1):2563-76.

Nakazato H, Koike A, Saji S, Ogawa N, Sakamoto J. Efficacy of immunochemotherapy as adjuvant treatment after curative resection of gastric cancer. Study Group of Immunochemotherapy with PSK for Gastric Cancer. Lancet. 1994;343(8906):1122-6.

Naveed S, Aslam M, Ahmad A. Starvation based differential chemotherapy: a novel approach for cancer treatment. Oman medical journal. Nov 2014;29(6):391-398.

Naziroglu M, Karaoglu A, Aksoy AO. Selenium and high dose vitamin E administration protects cisplatin-induced oxidative damage to renal, liver and lens tissues in rats. Toxicology. Feb 15 2004;195(2-3):221-230.

NCI. National Cancer Institute at National Institute of Health. Chemotherapy and You. Questions and Answers About Chemotherapy. How is chemotherapy given? Available at: 10/17/2014a. Accessed 08/22/2014.

NCI. National Cancer Institute at National Institute of Health. Hyperthermia in Cancer Treatment. Available at: Last updated 8/31/2011. Accessed 10/12/2014.

NCI. National Cancer Institute. Cancer Topics page. Nutrition Therapy. Available at: Last updated 6/25/2014b. Accessed 9/3/2014.

NCI. National Cancer Institute. Cancer Topics page. Targeted Cancer Therapies. Available at: 4/25/2014d. Accessed 1/21/2015.

NCI. National Cancer Institute. Chemotherapy and You: Support for People With Cancer. Side Effects and Ways To Manage Them: Constipation. Available at: 6/29/2007. Accessed 8/9/2014.

NCI. National Cancer Institute. Managing Chemotheapy Side Effects: Diarrhea. Available at: 2/2012. Accessed 10/24/2014.

NCI. National Cancer Institute. National Cancer Institute FactSheet. Targeted Cancer Therapies. Available at: Last updated 4/25/2014c. Accessed 8/27/2014.

Nelson MH, Diven MA, Huff LW, Paulos CM. Harnessing the Microbiome to Enhance Cancer Immunotherapy. J Immunol Res. 2015;2015:368736.

Neuss MN, Polovich M, McNiff K, Esper P, Gilmore TR, LeFebvre KB, . . . Jacobson JO. 2013 updated American Society of Clinical Oncology/Oncology Nursing Society chemotherapy administration safety standards including standards for the safe administration and management of oral chemotherapy. Journal of oncology practice / American Society of Clinical Oncology. 2013;9(2 Suppl):5s-13s.

Neuwelt EA, Pagel MA, Kraemer DF, Peterson DR, Muldoon LL. Bone marrow chemoprotection without compromise of chemotherapy efficacy in a rat brain tumor model. The Journal of pharmacology and experimental therapeutics. May 2004;309(2):594-599.

Nicolini A, Ferrari P, Masoni MC, Fini M, Pagani S, Giampietro O, Carpi A. Malnutrition, anorexia and cachexia in cancer patients: A mini-review on pathogenesis and treatment. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. Oct 2013;67(8):807-817.

Niimoto M, Hattori T, Tamada R, et al. Postoperative adjuvant immunochemotherapy with mitomycin C, futraful and PSK for gastric cancer. An analysis of data on 579 patients followed for five years. Jpn J Surg. 1988;18(6):681-6.

Nisar S, Feinfeld DA. N-acetylcysteine as salvage therapy in cisplatin nephrotoxicity. Renal failure. Jul 2002;24(4):529-533.

Nishijima S, Yanase T, Hata Y, Tamura R, Tsuneki I, Tamura M, Kurabayashi T. [Orally administered polaprezinc significantly improves taste disorders in ovarian cancer patient undergoing chemotherapy]. Gan To Kagaku Ryoho. 2011 Apr;38(4):689-92.

Nishijima S, Yanase T, Tsuneki I, Tamura M, Kurabayashi T. Examination of the taste disorder associated with gynecological cancer chemotherapy. Gynecol Oncol. 2013 Dec;131(3):674-8.

Nishiwaki Y, Furuse K, Fukuoka M, et al. [A randomized controlled study of PSK combined immuno-chemotherapy for adenocarcinoma of the lung. The Advanced Lung Cancer Immuno-chemotherapy Study Group]. Gan To Kagaku Ryoho. 1990;17(1):131-6.

NLM. U.S. National Library of Medicine. Enalapril. Section 7.8: Therapeutic Uses. Last updated 2/18/2017. Accessed 2/21/2017.

Noaman E, Badr El-Din NK, Bibars MA, Abou Mossallam AA, Ghoneum M. Antioxidant potential by arabinoxylan rice bran, MGN-3/biobran, represents a mechanism for its oncostatic effect against murine solid Ehrlich carcinoma. Cancer letters. Sep 18 2008;268(2):348-359.

Oei AL, Vriend LE, Crezee J, Franken NA, Krawczyk PM. Effects of hyperthermia on DNA repair pathways: one treatment to inhibit them all. Radiation oncology (London, England). Aug 07 2015;10:165.

Oh B, Butow P, Mullan B, Clarke S, Beale P, Pavlakis N, . . . Rosenthal D. Impact of medical Qigong on quality of life, fatigue, mood and inflammation in cancer patients: a randomized controlled trial. Annals of oncology : official journal of the European Society for Medical Oncology / ESMO. Mar 2010;21(3):608-614.

Ohkawa K, Tsukada Y, Dohzono H, Koike K, Terashima Y. The effects of co-administration of selenium and cis-platin (CDDP) on CDDP-induced toxicity and antitumour activity. British journal of cancer. Jul 1988;58(1):38-41.

Ohno S, Ohno Y, Suzuki N, Soma G, Inoue M. High-dose vitamin C (ascorbic acid) therapy in the treatment of patients with advanced cancer. Anticancer research. Mar 2009;29(3):809-815.

Ohwada S, Ikeya T, Yokomori T, et al. Adjuvant immunochemotherapy with oral Tegafur/Uracil plus PSK in patients with stage II or III colorectal cancer: a randomised controlled study. Br J Cancer. 2004;90(5):1003-10.

Ohwada S, Kawate S, Ikeya T,; Gunma Oncology Study Group (GOSG). Adjuvant therapy with protein-bound polysaccharide K and tegafur uracil in patients with stage II or III colorectal cancer: randomized, controlled trial. Dis Colon Rectum. 2003;46(8):1060-8.

Okonogi N, Ebara T, Ishikawa H, Yoshida D, Ueno M, Maeno T, Suga T, Nakano T. A 7-year disease-free survivor of malignant pleural mesothelioma treated with hyperthermia and chemotherapy: a case report. J Med Case Rep. 2012 Dec 28;6(1):427.

O'Rahilly R, Müller F, Carpenter S, Swenson R. Basic Human Anatomy. Chapter 3: The nerveous system. Available at: Copyright 2008. Accessed 1/16/2015.

Owusu RA, Abern MR, Inman BA. Hyperthermia as adjunct to intravesical chemotherapy for bladder cancer. Biomed Res Int. 2013;2013:262313

Ozcan A, Korkmaz A, Oter S, Coskun O. Contribution of flavonoid antioxidants to the preventive effect of mesna in cyclophosphamide-induced cystitis in rats. Arch Toxicol. 2005 Aug;79(8):461-5.

Pace A, Giannarelli D, Galie E, Savarese A, Carpano S, Della Giulia M, . . . Cognetti F. Vitamin E neuroprotection for cisplatin neuropathy: a randomized, placebo-controlled trial. Neurology. Mar 2 2010;74(9):762-766.

Pace A, Savarese A, Picardo M, Maresca V, Pacetti U, Del Monte G, . . . Bove L. Neuroprotective effect of vitamin E supplementation in patients treated with cisplatin chemotherapy. Journal of clinical oncology: official journal of the American Society of Clinical Oncology. Mar 1 2003;21(5):927-931.

Palatty PL, Haniadka R, Valder B, Arora R, Baliga MS. Ginger in the prevention of nausea and vomiting: a review. Crit Rev Food Sci Nutr. 2013;53(7):659-69

Palozza P, Serini S, Trombino S, Lauriola L, Ranelletti FO, Calviello G. Dual role of beta-carotene in combination with cigarette smoke aqueous extract on the formation of mutagenic lipid peroxidation products in lung membranes: dependence on pO2. Carcinogenesis. Dec 2006;27(12):2383-2391.

Panahi Y, Saadat A, Sahebkar A, Hashemian F, Taghikhani M, Abolhasani E. Effect of ginger on acute and delayed chemotherapy-induced nausea and vomiting: a pilot, randomized, open-label clinical trial. Integr Cancer Ther. 2012 Sep;11(3):204-11.

Park HJ. Chemotherapy induced peripheral neuropathic pain. Korean journal of anesthesiology. Jul 2014;67(1):4-7.

Park S. The effects of high concentrations of vitamin C on cancer cells. Nutrients. Sep 2013;5(9):3496-3505.

Pasquier E, Kavallaris M, Andre N. Metronomic chemotherapy: new rationale for new directions. Nature reviews. Clinical oncology. 2010;7(8):455-465.

Pathak AK, Bhutani M, Guleria R, Bal S, Mohan A, Mohanti BK, . . . Kochupillai V. Chemotherapy alone vs. chemotherapy plus high dose multiple antioxidants in patients with advanced non small cell lung cancer. Journal of the American College of Nutrition. Feb 2005;24(1):16-21.

Patil L, Balaraman R. Effect of green tea extract on Doxorubicin induced cardiovascular abnormalities: antioxidant action. Iranian journal of pharmaceutical research: IJPR. Winter 2011;10(1):89-96.

Patlakas G, Bouros D, Tsantekidou-Pozova S, Koukourakis MI. Triplet chemotherapy with docetaxel, gemcitabine and liposomal doxorubicin, supported with subcutaneous amifostine and hemopoietic growth factors, in advanced non-small cell lung cancer. Anticancer Res. 2005 Mar-Apr;25(2B):1427-31.

Perez Fidalgo JA, Garcia Fabregat L, Cervantes A, Margulies A, Vidall C, Roila F. Management of chemotherapy extravasation: ESMO-EONS Clinical Practice Guidelines. Annals of oncology: official journal of the European Society for Medical Oncology / ESMO. Oct 2012;23 Suppl 7:vii167-173.

Perez-Callejo D, Romero A, Provencio M, Torrente M. Liquid biopsy based biomarkers in non-small cell lung cancer for diagnosis and treatment monitoring. Transl Lung Cancer Res. Oct 2016;5(5):455-465.

Perry MC, Goldman L, Schafer AI. Goldman's Cecil Medicine, Twenty-Fourth Edition. Copyright 2012. Saunders, and imprint of Elsevier Inc. Chapter 182: Approach to the Patient with Cancer; 1164-1177.

Peters GJ, van der Wilt CL, van Moorsel CJ, Kroep JR, Bergman AM, Ackland SP. Basis for effective combination cancer chemotherapy with antimetabolites. Pharmacology & therapeutics. 2000;87(2-3):227-253.

Pfeil AM, Allcott K, Pettengell R, von Minckwitz G, Schwenkglenks M, Szabo Z. Efficacy, effectiveness and safety of long-acting granulocyte colony-stimulating factors for prophylaxis of chemotherapy-induced neutropenia in patients with cancer: a systematic review. Supportive care in cancer: official journal of the Multinational Association of Supportive Care in Cancer. Oct 7 2014.

Piatkowska-Jakubas B, Krawczyk-Kuliś M, Giebel S, et al. Use of L-asparaginase in acute lymphoblastic leukemia: recommendations of the Polish Adult Leukemia Group. Pol Arch Med Wewn. 2008;118(11):664-9.

Piccolo J, Kolesar JM. Prevention and treatment of chemotherapy-induced peripheral neuropathy. Am J Health Syst Pharm. 2014 Jan 1;71(1):19-25.

Piotrowski J, Jedrzejewski T, Kozak W. Immunomodulatory and antitumor properties of polysaccharide peptide (PSP). Postepy higieny i medycyny doswiadczalnej (Online). 2015;69(0):91-97.

Popovic M, Warr DG, Deangelis C, Tsao M, Chan KK, Poon M, Yip C, Pulenzas N, Lam H, Zhang L, Chow E. Efficacy and safety of palonosetron for the prophylaxis of chemotherapy-induced nausea and vomiting (CINV): a systematic review and meta-analysis of randomized controlled trials. Support Care Cancer. 2014 Jun;22(6):1685-97.

Pritchard JR, Lauffenburger DA, Hemann MT. Understanding Resistance to Combination Chemotherapy. Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy. Oct 2012;15(0):249-257.

Qazi A, Pal J, Maitah M, Fulciniti M, Pelluru D, Nanjappa P, . . . Shammas MA. Anticancer activity of a broccoli derivative, sulforaphane, in barrett adenocarcinoma: potential use in chemoprevention and as adjuvant in chemotherapy. Translational oncology. 2010;3(6):389-399.

Qiao J, Fang H. Hand-foot syndrome related to chemotherapy. CMAJ. 2012 Oct 16;184(15):E818.

Raeessi MA, Raeessi N, Panahi Y, Gharaie H, Davoudi SM, Saadat A, . . . Jalalian H. "Coffee plus honey" versus "topical steroid" in the treatment of chemotherapy-induced oral mucositis: a randomised controlled trial. BMC complementary and alternative medicine. 2014;14:293.

Raffa RB. Cancer 'survivor-care': II. Disruption of prefrontal brain activation top-down control of working memory capacity as possible mechanism for chemo-fog/brain (chemotherapy-associated cognitive impairment). J Clin Pharm Ther. 2013 Aug;38(4):265-8.

Raffaghello L, Safdie F, Bianchi G, Dorff T, Fontana L, Longo VD. Fasting and differential chemotherapy protection in patients. Cell Cycle. 2010 Nov 15;9(22):4474-6.

Rajendran P, Li F, Manu KA, Shanmugam MK, Loo SY, Kumar AP, Sethi G. gamma-Tocotrienol is a novel inhibitor of constitutive and inducible STAT3 signalling pathway in human hepatocellular carcinoma: potential role as an antiproliferative, pro-apoptotic and chemosensitizing agent. British journal of pharmacology. 2011;163(2):283-298.

Randall J, Ream E. Hair loss with chemotherapy: at a loss over its management? European journal of cancer care. Jul 2005;14(3):223-231.

Ravid A, Rocker D, Machlenkin A, Rotem C, Hochman A, Kessler-Icekson G, Liberman UA, Koren R. 1,25-Dihydroxyvitamin D3 enhances the susceptibility of breast cancer cells to doxorubicin-induced oxidative damage. Cancer Res. 1999 Feb 15;59(4):862-7.

Ray SD, Patel D, Wong V, Bagchi D. In vivo protection of dna damage associated apoptotic and necrotic cell deaths during acetaminophen-induced nephrotoxicity, amiodarone-induced lung toxicity and doxorubicin-induced cardiotoxicity by a novel IH636 grape seed proanthocyanidin extract. Research communications in molecular pathology and pharmacology. 2000;107(1-2):137-166.

Reagan-Shaw S, Nihal M, Ahmad N. Dose translation from animal to human studies revisited. FASEB journal: official publication of the Federation of American Societies for Experimental Biology. Mar 2008;22(3):659-661.

Redman MG, Ward EJ, Phillips RS. The efficacy and safety of probiotics in people with cancer: a systematic review. Annals of oncology: official journal of the European Society for Medical Oncology / ESMO. Oct 2014;25(10):1919-1929.

Remesh A. Tackling the problems of tumour chemotherapy by optimal drug scheduling. J Clin Diagn Res. 2013;7(7):1404-7.

Repetto L. Incidence and clinical impact of chemotherapy induced myelotoxicity in cancer patients: An observational retrospective survey. Critical reviews in oncology/hematology. 2009;72(2):170-179.

Revicki DA, Stull D, Vernon M, Rader M, Tomita D, Viswanathan HN. Assessing the effect of darbepoetin alfa on patient-reported fatigue in chemotherapy-induced anemia in 4 randomized, placebo-controlled clinical trials. Qual Life Res. 2012 Mar;21(2):311-21.

Rice M. Management of Chemotherapy-Induced Nausea and Vomiting. Last updated 7/16/2011. Accessed 2/21/2017.

Rice SD, Heinzman JM, Brower SL, Ervin PR, Song N, Shen K, Wang D. Analysis of chemotherapeutic response heterogeneity and drug clustering based on mechanism of action using an in vitro assay. Anticancer research. Jul 2010;30(7):2805-2811.

Ries F, Klastersky J. Nephrotoxicity induced by cancer chemotherapy with special emphasis on cisplatin toxicity. American journal of kidney diseases: the official journal of the National Kidney Foundation. Nov 1986;8(5):368-379.

Rivenbark AG, O'Connor SM, Coleman WB. Molecular and cellular heterogeneity in breast cancer: challenges for personalized medicine. The American journal of pathology. Oct 2013;183(4):1113-1124.

Rodier F, Campisi J. Four faces of cellular senescence. The Journal of Cell Biology. February 21, 2011 2011;192(4):547-556.

Roffe L, Schmidt K, Ernst E. Efficacy of coenzyme Q10 for improved tolerability of cancer treatments: a systematic review. Journal of clinical oncology: official journal of the American Society of Clinical Oncology. Nov 1 2004;22(21):4418-4424.

Rostock M, Huber R, Greiner T, Fritz P, Scheer R, Schueler J, Fiebig HH. Anticancer activity of a lectin-rich mistletoe extract injected intratumorally into human pancreatic cancer xenografts. Anticancer research. May-Jun 2005;25(3b):1969-1975.

Ruiz Garcia V, López-Briz E, Carbonell Sanchis R, Gonzalvez Perales JL, Bort-Marti S. Megestrol acetate for treatment of anorexia-cachexia syndrome. Cochrane Database Syst Rev. 2013 Mar 28;3:CD004310.

Rusciani L, Proietti I, Paradisi A, Rusciani A, Guerriero G, Mammone A, . . . Lippa S. Recombinant interferon alpha-2b and coenzyme Q10 as a postsurgical adjuvant therapy for melanoma: a 3-year trial with recombinant interferon-alpha and 5-year follow-up. Melanoma research. Jun 2007;17(3):177-183.

Rushworth GF, Megson IL. Existing and potential therapeutic uses for N-acetylcysteine: the need for conversion to intracellular glutathione for antioxidant benefits. Pharmacology & therapeutics. Feb 2014;141(2):150-159.

Rutgers E, Piccart-Gebhart MJ, Bogaerts J, Delaloge S, Veer LV, Rubio IT, Viale G, Thompson AM, Passalacqua R, Nitz U, Vindevoghel A, Pierga JY, Ravdin PM, Werutsky G, Cardoso F. The EORTC 10041/BIG 03-04 MINDACT trial is feasible: results of the pilot phase. Eur J Cancer. 2011 Dec;47(18):2742-9.

Ryan JL, Heckler CE, Roscoe JA, Dakhil SR, Kirshner J, Flynn PJ, Hickok JT, Morrow GR. Ginger (Zingiber officinale) reduces acute chemotherapy-induced nausea: a URCC CCOP study of 576 patients. Support Care Cancer. 2012 Jul;20(7):1479-89.

Sabaawy HE. Genetic Heterogeneity and Clonal Evolution of Tumor Cells and their Impact on Precision Cancer Medicine. Journal of leukemia (Los Angeles, Calif.). Nov 18 2013;1(4):1000124.

Sacks CA, Jarcho JA, Curfman GD. Paradigm Shifts in Heart-Failure Therapy — A Timeline. New England Journal of Medicine. 2014;371(11):989-991.

Sadzuka Y, Matsuura M, Sonobe T. The effect of taurine, a novel biochemical modulator, on the antitumor activity of doxorubicin. Biol Pharm Bull. 2009;32(9):1584-7.

Sadzuka Y, Sugiyama T, Hirota S. Modulation of cancer chemotherapy by green tea. Clin Cancer Res. 1998;4(1):153-6.

Safdie F, Brandhorst S, Wei M, Wang W, Lee C, Hwang S, . . . Longo VD. Fasting enhances the response of glioma to chemo- and radiotherapy. PloS one. 2012;7(9):e44603.

Safdie FM, Dorff T, Quinn D, Fontana L, Wei M, Lee C, . . . Longo VD. Fasting and cancer treatment in humans: A case series report. Aging. Dec 2009;1(12):988-1007.

Sak K. Chemotherapy and dietary phytochemical agents. Chemotherapy research and practice. 2012;2012:282570.

Saleh EM, El-awady RA, Eissa NA, Abdel-Rahman WM. Antagonism between curcumin and the topoisomerase II inhibitor etoposide: a study of DNA damage, cell cycle regulation and death pathways. Cancer biology & therapy. Sep 2012;13(11):1058-1071.

Salva S, Marranzino G, Villena J, Aguero G, Alvarez S. Probiotic Lactobacillus strains protect against myelosuppression and immunosuppression in cyclophosphamide-treated mice. International immunopharmacology. Sep 2014;22(1):209-221.

Samuni Y, Goldstein S, Dean OM, Berk M. The chemistry and biological activities of N-acetylcysteine. Biochimica et biophysica acta. Aug 2013;1830(8):4117-4129.

Sánchez-Lara K, Sosa-Sánchez R, Green-Renner D, Rodríguez C, Laviano A, Motola-Kuba D, Arrieta O. Influence of taste disorders on dietary behaviors in cancer patients under chemotherapy.Nutr J. 2010 Mar 24;9:15.

Sapra P, Betts A, Boni J. Preclinical and clinical pharmacokinetic/pharmacodynamic considerations for antibody-drug conjugates. Expert review of clinical pharmacology. Sep 2013;6(5):541-555.

Sasaki H, Sunagawa Y, Takahashi K, Imaizumi A, Fukuda H, Hashimoto T, . . . Morimoto T. Innovative preparation of curcumin for improved oral bioavailability. Biological & pharmaceutical bulletin. 2011;34(5):660-665.

Sato J, Kudo K, Hino K, Takahashi K. [Usefulness of oral rehydration solution for hydration in cancer chemotherapy: toward the application of outpatient chemotherapy with high-dose Cisplatin therapy-]. Gan to kagaku ryoho. Cancer & chemotherapy. Sep 2011;38(9):1471-1476.

Satoh H, Nishikawa K, Suzuki K, Asano R, Virgona N, Ichikawa T, Hagiwara K, Yano T. Genistein, a soy isoflavone, enhances necrotic-like cell death in a breast cancer cell treated with a chemotherapeutic agent. Res Commun Mol Pathol Pharmacol. 2003;113-114:149-58.

Sayed-Ahmed MM, Al-Shabanah OA, Hafez MM, Aleisa AM, Al-Rejaie SS. Inhibition of gene expression of heart fatty acid binding protein and organic cation/carnitine transporter in doxorubicin cardiomyopathic rat model. European journal of pharmacology. Aug 25 2010;640(1-3):143-149.

Sayed-Ahmed MM, Eissa MA, Kenawy SA, Mostafa N, Calvani M, Osman AM. Progression of cisplatin-induced nephrotoxicity in a carnitine-depleted rat model. Chemotherapy. Oct 2004;50(4):162-170.

Sayed-Ahmed MM, Hafez MM, Aldelemy ML, Aleisa AM, Al-Rejaie SS, Al-Hosaini KA, . . . Al-Shabanah OA. Downregulation of oxidative and nitrosative apoptotic signaling by L-carnitine in Ifosfamide-induced Fanconi syndrome rat model. Oxidative medicine and cellular longevity. 2012;2012:696704.

Sayed-Ahmed MM. Role of carnitine in cancer chemotherapy-induced multiple organ toxicity. Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society. Oct 2010;18(4):195-206.

Schad F, Atxner J, Buchwald D, Happe A, Popp S, Kroz M, Matthes H. Intratumoral Mistletoe (Viscum album L) Therapy in Patients With Unresectable Pancreas Carcinoma: A Retrospective Analysis. Integrative cancer therapies. Dec 19 2013;13(4):332-340.

Scharovsky OG, Mainetti LE, Rozados VR. Metronomic chemotherapy: changing the paradigm that more is better. Current oncology (Toronto, Ont.). 2009;16(2):7-15.

Schiller JH, Storer B, Berlin J, Wittenkeller J, Larson M, Pharo L, Larson M, Berry W. Amifostine, cisplatin, and vinblastine in metastatic non-small-cell lung cancer: a report of high response rates and prolonged survival. J Clin Oncol. 1996 Jun;14(6):1913-21.

Schlemmer M, Suchner U, Schapers B, Duerr EM, Alteheld B, Zwingers T, . . . Zimmer HG. Is glutamine deficiency the link between inflammation, malnutrition, and fatigue in cancer patients? Clinical nutrition (Edinburgh, Scotland). Jan 10 2015.

Schmidinger M, Budinsky AC, Wenzel C, Piribauer M, Brix R, Kautzky M, . . . Steger GG. Glutathione in the prevention of cisplatin induced toxicities. A prospectively randomized pilot trial in patients with head and neck cancer and non small cell lung cancer. Wiener klinische Wochenschrift. Jul 28 2000;112(14):617-623.

Schuchter LM. Guidelines for the administration of amifostine. Seminars in oncology. Aug 1996;23(4 Suppl 8):40-43.

Schwartzberg L, Barbour SY, Morrow GR, Ballinari G, Thorn MD, Cox D. Pooled analysis of phase III clinical studies of palonosetron versus ondansetron, dolasetron, and granisetron in the prevention of chemotherapy-induced nausea and vomiting (CINV). Supportive care in cancer: official journal of the Multinational Association of Supportive Care in Cancer. Feb 2014;22(2):469-477.

Seely D, Wu P, Fritz H, Kennedy DA, Tsui T, Seely AJ, Mills E. Melatonin as adjuvant cancer care with and without chemotherapy: a systematic review and meta-analysis of randomized trials. Integrative cancer therapies. Dec 2012;11(4):293-303.

Segal EM, Flood MR, Mancini RS, Whiteman RT, Friedt GA, Kramer AR, Hofstetter MA. Oral chemotherapy food and drug interactions: a comprehensive review of the literature. Journal of oncology practice / American Society of Clinical Oncology. Jul 2014;10(4):e255-268.

Seicean S, Seicean A, Plana JC, Budd GT, Marwick TH. Effect of statin therapy on the risk for incident heart failure in patients with breast cancer receiving anthracycline chemotherapy: an observational clinical cohort study. J Am Coll Cardiol. 2012 Dec 11;60(23):2384-90.

Seifried HE, McDonald SS, Anderson DE, Greenwald P, Milner JA. The Antioxidant Conundrum in Cancer. Cancer research. August 1, 2003 2003;63(15):4295-4298.

Selli C, Dixon JM, Sims AH. Accurate prediction of response to endocrine therapy in breast cancer patients: current and future biomarkers. Breast cancer research: BCR. Dec 01 2016;18(1):118.

Senthilnathan P, Padmavathi R, Banu SM, Sakthisekaran D. Enhancement of antitumor effect of paclitaxel in combination with immunomodulatory Withania somnifera on benzo(a)pyrene induced experimental lung cancer. Chem Biol Interact. 2006 Feb 25;159(3):180-5.

Shahbazi F, Dashti-Khavidaki S, Khalili H, et al. Potential Renoprotective Effects of Silymarin Against Nephrotoxic Drugs: A Review of Literature. J Pharm Pharmaceut Sci. 2012;15(1):112-123.

Shaikh IA, Brown I, Wahle KW, Heys SD. Enhancing cytotoxic therapies for breast and prostate cancers with polyunsaturated fatty acids. Nutrition and cancer. 2010;62(3):284-296.

Shakibaei M, Buhrmann C, Kraehe P, Shayan P, Lueders C, Goel A. Curcumin chemosensitizes 5-fluorouracil resistant MMR-deficient human colon cancer cells in high density cultures. PLoS One. 2014;9(1):e85397.

Shapiro TA, Fahey JW, Dinkova-Kostova AT, Holtzclaw WD, Stephenson KK, Wade KL, . . . Talalay P. Safety, tolerance, and metabolism of broccoli sprout glucosinolates and isothiocyanates: a clinical phase I study. Nutrition and cancer. 2006;55(1):53-62.

Shatoor AS, Ahmed MAAS. syn. Azarolus (L) Aqueous Extract Against Doxorubicin-Induced Cardiotoxicity and Heart Failure in Wistar Rats. 2014.

SHCI. The Scott Hamilton CARES Initiative. Chemotherapy Terms. Available at: Accessed 8/7/2014.

SHCI. The Scott Hamilton CARES Initiative. How Is Chemotherapy Given? Available at: Accessed 2/16/2017.

Sheikh-Hamad D, Timmins K, Jalali Z. Cisplatin-induced renal toxicity: possible reversal by N-acetylcysteine treatment. Journal of the American Society of Nephrology: JASN. Oct 1997;8(10):1640-1644.

Shelygin Iu A, Alekseev MV, Rybakov EG, Eropkin PV. [Effect of intraoperative intrapelvic chemotherapy with hyperthermia on the incidence of rectal cancer recurrences]. Voprosy onkologii. 2014;60(1):64-70.

Shen J, Tai YC, Zhou J, Stephen Wong CH, Cheang PT, Fred Wong WS, Xie Z, Khan M, Han JH, Chen CS. Synergistic antileukemia effect of genistein and chemotherapy in mouse xenograft model and potential mechanism through MAPK signaling. Exp Hematol. 2007 Jan;35(1):75-83.

Shen M, Chan TH, Dou QP. Targeting tumor ubiquitin-proteasome pathway with polyphenols for chemosensitization. Anti-cancer agents in medicinal chemistry. 2012;12(8):891-901.

Shen WS, Gao CH, Zhang H. [Effect of rhodiola on serum troponin 1, cardiac integral backscatter and left ventricle ejective fraction of patients who received epirubicin-contained chemotherapy]. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2010;30(12):1250-2.

Silverio R, Laviano A, Rossi Fanelli F, Seelaender M. l-carnitine and cancer cachexia: Clinical and experimental aspects. Journal of cachexia, sarcopenia and muscle. Mar 2011;2(1):37-44.

Simone CB 2nd, Simone NL, Simone V, Simone CB. Antioxidants and other nutrients do not interfere with chemotherapy or radiation therapy and can increase kill and increase survival, Part 2. Altern Ther Health Med. 2007b;13(2):40-7

Simone CB, 2nd, Simone NL, Simone V, Simone CB. Antioxidants and other nutrients do not interfere with chemotherapy or radiation therapy and can increase kill and increase survival, Part 1. Altern Ther Health Med. 2007a;13(1):22-28.

Singh U, Devaraj S, Jialal I. Coenzyme Q10 supplementation and heart failure. Nutrition reviews. Jun 2007;65(6 Pt 1):286-293.

Skinner HD, McCurdy MR, Echeverria AE, Lin SH, Welsh JW, O'Reilly MS, . . . Guerrero TM. Metformin use and improved response to therapy in esophageal adenocarcinoma. Acta oncologica (Stockholm, Sweden). 2013;52(5):1002-1009.

Skitzki JJ, Repasky EA, Evans SS. Hyperthermia as an immunotherapy strategy for cancer. Current opinion in investigational drugs (London, England: 2000). Jun 2009;10(6):550-558.

Slater S. Non-curative chemotherapy for cancer--is it worth it? Clinical medicine (London, England). May-Jun 2001;1(3):220-222.

Slodkowska EA, Ross JS. MammaPrint 70-gene signature: another milestone in personalized medical care for breast cancer patients. Expert review of molecular diagnostics. Jul 2009;9(5):417-422.

Smith EM, Pang H, Cirrincione C, Fleishman S, Paskett ED, Ahles T, . . . Shapiro CL. Effect of duloxetine on pain, function, and quality of life among patients with chemotherapy-induced painful peripheral neuropathy: a randomized clinical trial. Jama. Apr 03 2013;309(13):1359-1367.

Smith HS, Zoli W, Volpi A, Hiller A, Lippman M, Swain S, Mayall B, Dollbaum C, Hackett AJ, Amadori D. Preliminary correlations of clinical outcome with in vitro chemosensitivity of second passage human breast cancer cells. Cancer Res. 1990 May 15;50(10):2943-8.

Smith SC, Baras AS, Lee JK, Theodorescu D. The COXEN principle: translating signatures of in vitro chemosensitivity into tools for clinical outcome prediction and drug discovery in cancer. Cancer Res. 2010 Mar 1;70(5):1753-8.

Smyth JF, Bowman A, Perren T, Wilkinson P, Prescott RJ, Quinn KJ, Tedeschi M. Glutathione reduces the toxicity and improves quality of life of women diagnosed with ovarian cancer treated with cisplatin: results of a double-blind, randomised trial. Annals of oncology: official journal of the European Society for Medical Oncology / ESMO. Jun 1997;8(6):569-573.

Solanki MH, Chatterjee PK, Gupta M, Xue X, Plagov A, Metz MH, . . . Metz CN. Magnesium protects against cisplatin-induced acute kidney injury by regulating platinum accumulation. American journal of physiology. Renal physiology. Aug 15 2014;307(4):F369-384.

Solheim TS, Laird BJ. Evidence base for multimodal therapy in cachexia. Current opinion in supportive and palliative care. Dec 2012;6(4):424-431.

Somasundaram S, Edmund NA, Moore DT, et al. Dietary curcumin inhibits chemotherapy-induced apoptosis in models of human breast cancer. Cancer Res. 2002 Jul 1;62(13):3868-3875.

Song J, Liu D, Feng L, Zhang Z, Jia X, Xiao W. Protective Effect of Standardized Extract of Ginkgo biloba against Cisplatin-Induced Nephrotoxicity. Evidence-based complementary and alternative medicine : eCAM. 2013;2013:846126.

Sonneveld P. Effect of alpha-tocopherol on the cardiotoxicity of adriamycin in the rat. Cancer treatment reports. Jul 1978;62(7):1033-1036.

Soref CM, Hacker TA, Fahl WE. A new orally active, aminothiol radioprotector-free of nausea and hypotension side effects at its highest radioprotective doses. International journal of radiation oncology, biology, physics. Apr 1 2012;82(5):e701-707.

Soritau O, Tomuleasa C, Aldea M, Petrushev B, Susman S, Gheban D, Ioani H, Cosis A, Brie I, Irimie A, Kacso G, Florian IS. Metformin plus temozolomide-based chemotherapy as adjuvant treatment for WHO grade III and IV malignant gliomas. J BUON. 2011;16(2):282-9.

Spagnuolo C, Russo GL, Orhan IE, Habtemariam S, Daglia M, Sureda A, . . . Nabavi SM. Genistein and cancer: current status, challenges, and future directions. Adv Nutr. Jul 2015;6(4):408-419.

Speck RM, DeMichele A, Farrar JT, Hennessy S, Mao JJ, Stineman MG, Barg FK. Scope of symptoms and self-management strategies for chemotherapy-induced peripheral neuropathy in breast cancer patients. Support Care Cancer. 2012 Oct;20(10):2433-9.

Spencer A, Horvath N, Gibson J, Prince HM, Herrmann R, Bashford J, Joske D, Grigg A, McKendrick J, Prosser I, Lowenthal R, Deveridge S, Taylor K; Australasian Leukemia and Lymphoma Group. Prospective randomised trial of amifostine cytoprotection in myeloma patients undergoing high-dose melphalan conditioned autologous stem cell transplantation. Bone Marrow Transplant. 2005 May;35(10):971-7.

Sreekanth CN, Bava SV, Sreekumar E, Anto RJ. Molecular evidences for the chemosensitizing efficacy of liposomal curcumin in paclitaxel chemotherapy in mouse models of cervical cancer. Oncogene. Jul 14 2011;30(28):3139-3152.

Steele ML, Axtner J, Happe A, Kroz M, Matthes H, Schad F. Safety of Intravenous Application of Mistletoe (Viscum album L.) Preparations in Oncology: An Observational Study. Evidence-based complementary and alternative medicine: eCAM. 2014;2014:236310.

Steele ML, Axtner J, Happe A, Kroz M, Matthes H, Schad F. Use and safety of intratumoral application of European mistletoe (Viscum album L) preparations in Oncology. Integrative cancer therapies. Mar 2015;14(2):140-148.

Steele ML, Axtner J. Adverse Drug Reactions and Expected Effects to Therapy with Subcutaneous Mistletoe Extracts (Viscum album L.) in Cancer Patients. 2014;2014:724258.

Steinbach S, Hundt W, Schmalfeldt B, Böhner C, Berktold S, Wolf P, Harbeck N. Effect of platinum-containing chemotherapy on olfactory, gustatory, and hearing function in ovarian cancer patients. Arch Gynecol Obstet. 2012 Aug;286(2):473-80.

Steiner R, Hellmann K. Dexrazoxane prevention of anthracycline cardiomyopathy. J Clin Oncol. 2013 Apr 1;31(10):1379.

Sterba M, Popelova O, Vavrova A, Jirkovsky E, Kovarikova P, Gersl V, Simunek T. Oxidative stress, redox signaling, and metal chelation in anthracycline cardiotoxicity and pharmacological cardioprotection. Antioxidants & redox signaling. Mar 10 2013;18(8):899-929.

Stewart T, Pavlakis N, Ward M. Cardiotoxicity with 5-fluorouracil and capecitabine: more than just vasospastic angina. Internal medicine journal. Apr 2010;40(4):303-307.

Stipp D. How Intermittent Fasting Might Help You Live a Longer and Healthier Life - Scientific American. Accessed 7/24/2015.

Stubblefield MD, McNeely ML, Alfano CM, Mayer DK. A prospective surveillance model for physical rehabilitation of women with breast cancer: chemotherapy-induced peripheral neuropathy. Cancer. 2012 Apr 15;118(8 Suppl):2250-60.

Subbiah MT, Yunker R. Studies on the nature of anti-platelet aggregatory factors in the seeds of the Amazonian Herb Guarana (Paullinia cupana). International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition. Mar 2008;78(2):96-101.

Sugiyama T, Sadzuka Y, Nagasawa K, Ohnishi N, Yokoyama T, Sonobe T. Membrane transport and antitumor activity of pirarubicin, and comparison with those of doxorubicin. Japanese journal of cancer research: Gann. Jul 1999;90(7):775-780.

Sugiyama T, Sadzuka Y. Theanine and glutamate transporter inhibitors enhance the antitumor efficacy of chemotherapeutic agents. Biochimica et biophysica acta. Dec 5 2003;1653(2):47-59.

Sun J, Wang H, Hu H. Glutamine for chemotherapy induced diarrhea: a meta-analysis. Asia Pac J Clin Nutr. 2012;21(3):380-5

Sunagawa Y, Hirano S, Katanasaka Y, Miyazaki Y, Funamoto M, Okamura N, . . . Morimoto T. Colloidal submicron-particle curcumin exhibits high absorption efficiency-a double-blind, 3-way crossover study. J Nutr Sci Vitaminol (Tokyo). 2015;61(1):37-44.

Sung B, Kunnumakkara AB, Sethi G, Anand P, Guha S, Aggarwal BB. Curcumin circumvents chemoresistance in vitro and potentiates the effect of thalidomide and bortezomib against human multiple myeloma in nude mice model. Molecular cancer therapeutics. Apr 2009;8(4):959-970.

Taherian-Fard A, Srihari S, Ragan MA. Breast cancer classification: linking molecular mechanisms to disease prognosis. Briefings in bioinformatics. Jun 20 2014.

Taillibert S. Is systemic anti-cancer therapy neurotoxic? Does chemo brain exist? And should we rename it? Adv Exp Med Biol. 2010;678:86-95.

Taixiang W, Munro AJ, Guanjian L. Chinese medical herbs for chemotherapy side effects in colorectal cancer patients. Cochrane Database Syst Rev. 2005 Jan 25;(1):CD004540.

Takagi K, Yamamori H, Furukawa K, Miyazaki M, Tashiro T. Perioperative supplementation of EPA reduces immunosuppression induced by postoperative chemoradiation therapy in patients with esophageal cancer. Nutrition (Burbank, Los Angeles County, Calif.). Jun 2001;17(6):478-479.

Takahashi Y, Mai M, Nakazato H. Preoperative CEA and PPD values as prognostic factors for immunochemotherapy using PSK and 5-FU. Anticancer Res. 2005;25(2B):1377-84.

Takimoto CH. New Antifolates: Pharmacology and Clinical Applications. The oncologist. 1996;1(1 & 2):68-81.

Tan BX, Yao WX, Ge J, Peng XC, Du XB, Zhang R, Yao B, Xie K, Li LH, Dong H, Gao F, Zhao F, Hou JM, Su JM, Liu JY. Prognostic influence of metformin as first-line chemotherapy for advanced nonsmall cell lung cancer in patients with type 2 diabetes. Cancer. 2011;117(22):5103-11.

Tao LM, Xiong JP, Liu TX. [A crossover control study of prophylactic treatment of chemotherapy-induced constipation by senna extract]. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2012 Jan;32(1):47-9.

Taso CJ, Lin HS, Lin WL, Chen SM, Huang WT, Chen SW. The effect of yoga exercise on improving depression, anxiety, and fatigue in women with breast cancer: a randomized controlled trial. The journal of nursing research: JNR. Sep 2014;22(3):155-164.

Taylor CW, Wang LM, List AF, Fernandes D, Paine-Murrieta GD, Johnson CS, Capizzi RL. Amifostine protects normal tissues from paclitaxel toxicity while cytotoxicity against tumour cells is maintained. European journal of cancer (Oxford, England: 1990). Sep 1997;33(10):1693-1698.

Teiten MH, Eifes S, Dicato M, Diederich M. Curcumin-the paradigm of a multi-target natural compound with applications in cancer prevention and treatment. Toxins. Jan 2010;2(1):128-162.

Thomas Dickey D, Muldoon LL, Kraemer DF, Neuwelt EA. Protection against cisplatin-induced ototoxicity by N-acetylcysteine in a rat model. Hearing research. Jul 2004;193(1-2):25-30.

Tierney AJ, Leonard RC, Taylor J, Closs SJ, Chetty U, Rodger A. Side effects expected and experienced by women receiving chemotherapy for breast cancer. BMJ. 1991 Feb 2;302(6771):272.

Timmer-Bonte JN, de Boo TM, Smit HJ, Biesma B, Wilschut FA, Cheragwandi SA, . . . Tjan-Heijnen VC. Prevention of chemotherapy-induced febrile neutropenia by prophylactic antibiotics plus or minus granulocyte colony-stimulating factor in small-cell lung cancer: a Dutch Randomized Phase III Study. Journal of clinical oncology: official journal of the American Society of Clinical Oncology. Nov 1 2005;23(31):7974-7984.

Timmer-Bonte JN, Tjan-Heijnen VC. Febrile neutropenia: highlighting the role of prophylactic antibiotics and granulocyte colony-stimulating factor during standard dose chemotherapy for solid tumors. Anti-cancer drugs. Sep 2006;17(8):881-889.

Tiseo M, Martelli O, Mancuso A, Sormani MP, Bruzzi P, Di Salvia R, . . . Ardizzoni A. Short hydration regimen and nephrotoxicity of intermediate to high-dose cisplatin-based chemotherapy for outpatient treatment in lung cancer and mesothelioma. Tumori. Mar-Apr 2007;93(2):138-144.

Toden S, Okugawa Y, Jascur T, Wodarz D, Komarova NL, Buhrmann C, . . . Goel A. Curcumin mediates chemosensitization to 5-fluorouracil through miRNA-induced suppression of epithelial-to-mesenchymal transition in chemoresistant colorectal cancer. Carcinogenesis. Feb 4 2015.

Todorova V, Vanderpool D, Blossom S, Nwokedi E, Hennings L, Mrak R, Klimberg VS. Oral glutamine protects against cyclophosphamide-induced cardiotoxicity in experimental rats through increase of cardiac glutathione. Nutrition (Burbank, Los Angeles County, Calif.). 2009;25(7–8):812-817.

Toge T, Yamaguchi Y. Protein-bound polysaccharide increases survival in resected gastric cancer cases stratified with a preoperative granulocyte and lymphocyte count. Oncol Rep. 2000;7(5):1157-1161.

Topkan E, Parlak C, Topuk S, Pehlivan B. Influence of oral glutamine supplementation on survival outcomes of patients treated with concurrent chemoradiotherapy for locally advanced non-small cell lung cancer. BMC cancer. 2012;12:502.

Torne SJ, Ansari KA, Vavia PR, Trotta F, Cavalli R. Enhanced oral paclitaxel bioavailability after administration of paclitaxel-loaded nanosponges. Drug delivery. 2010;17(6):419-425.

Totsuka O, Kawate S, Hirai K, et al. [Subset analysis of preoperative lymphocyte ratio in stage II or III colorectal cancer patients treated with oral tegafur-uracil and protein-bound polysaccharide K]. Gan To Kagaku Ryoho. 2013;40(13):2525-8.

Troger W, Zdrale Z, Tisma N, Matijasevic M. Additional Therapy with a Mistletoe Product during Adjuvant Chemotherapy of Breast Cancer Patients Improves Quality of Life: An Open Randomized Clinical Pilot Trial. Evidence-based complementary and alternative medicine: eCAM. 2014;2014:430518.

Tröger W, Zdrale Z, Tisma N, Matijasevic M. Additional Therapy with a Mistletoe Product during Adjuvant Chemotherapy of Breast Cancer Patients Improves Quality of Life: An Open Randomized Clinical Pilot Trial. Evidence-based complementary and alternative medicine: eCAM. 2014;2014:430518.

Tsujimoto T, Yamamoto Y, Wasa M, Takenaka Y, Nakahara S, Takagi T, . . . Ito T. L-glutamine decreases the severity of mucositis induced by chemoradiotherapy in patients with locally advanced head and neck cancer: a double-blind, randomized, placebo-controlled trial. Oncol Rep. Jan 2015;33(1):33-39.

Tufekci O, Gunes D, Ozogul C, Kolatan E, Altun Z, Yilmaz O, . . . Olgun N. Evaluation of the effect of acetyl L-carnitine on experimental cisplatin nephrotoxicity. Chemotherapy. 2009;55(6):451-459.

Ugurel S, Utikal J, Becker JC. Tumor biomarkers in melanoma. Cancer control : journal of the Moffitt Cancer Center. Jul 2009;16(3):219-224.

Uma Mahesh B, Shrivastava S, Kuncha M, Sahu BD, Swamy CV, Pragada RR, . . . Sistla R. Ethanolic extract of Boswellia ovalifoliolata bark and leaf attenuates doxorubicin-induced cardiotoxicity in mice. Environmental toxicology and pharmacology. Nov 2013;36(3):840-849.

Urschel JD, Vasan H, Blewett CJ. A meta-analysis of randomized controlled trials that compared neoadjuvant chemotherapy and surgery to surgery alone for resectable esophageal cancer. American journal of surgery. Mar 2002;183(3):274-279.

Vaclavikova R, Horsky S, Simek P, Gut I. Paclitaxel metabolism in rat and human liver microsomes is inhibited by phenolic antioxidants. Naunyn-Schmiedeberg's archives of pharmacology. Sep 2003;368(3):200-209.

Vadhan-Raj S. Management of chemotherapy-induced thrombocytopenia: current status of thrombopoietic agents. Seminars in hematology. Jan 2009;46(1 Suppl 2):S26-32.

Vahdat L, Papadopoulos K, Lange D, Leuin S, Kaufman E, Donovan D, . . . Balmaceda C. Reduction of paclitaxel-induced peripheral neuropathy with glutamine. Clinical cancer research: an official journal of the American Association for Cancer Research. May 2001;7(5):1192-1197.

van Dalen EC, Caron HN, Dickinson HO, Kremer LC. Cardioprotective interventions for cancer patients receiving anthracyclines. The Cochrane database of systematic reviews. 2011(6):Cd003917.

van Dalen EC, van den Berg H, Raphaël MF, Caron HN, Kremer LC. Should anthracyclines and dexrazoxane be used for children with cancer? Lancet Oncol. 2011 Jan;12(1):12-3.

van den Hurk CJ, van de Poll-Franse LV, Breed WP, Coebergh JW, Nortier JW. Scalp cooling to prevent alopecia after chemotherapy can be considered safe in patients with breast cancer. Breast. 2013 Oct;22(5):1001-4

Verstappen CC, Heimans JJ, Hoekman K, Postma TJ. Neurotoxic complications of chemotherapy in patients with cancer: clinical signs and optimal management. Drugs. 2003;63(15):1549-1563.

Viale PH. Integrating aprepitant and palonosetron into clinical practice: a role for the new antiemetics. Clinical journal of oncology nursing. Feb 2005;9(1):77-84.

Victorino VJ, Pizzatti L, Michelletti P, Panis C. Oxidative stress, redox signaling and cancer chemoresistance: putting together the pieces of the puzzle. Current medicinal chemistry. 2014;21(28):3211-3226.

Vidall C, Roe H, Dougherty L, Harrold K. Dexrazoxane: a management option for anthracycline extravasations. Br J Nurs. 2013 Sep 12-25;22(17):S6 -12.

Vinod BS, Maliekal TT, Anto RJ. Phytochemicals as chemosensitizers: from molecular mechanism to clinical significance. Antioxid Redox Signal. 2013;18(11):1307-48.

Visovsky C, Schneider S. Cancer-Related Fatigue. Online Journal of Issues in Nursing. 2003;8(3).

Von Bultzingslowen I, Adlerberth I, Wold AE, Dahlen G, Jontell M. Oral and intestinal microflora in 5-fluorouracil treated rats, translocation to cervical and mesenteric lymph nodes and effects of probiotic bacteria. Oral Microbiol Immunol. Oct 2003;18(5):278-284.

Vrabel M. Is ondansetron more effective than granisetron for chemotherapy-induced nausea and vomiting? A review of comparative trials. Clinical journal of oncology nursing. Dec 2007;11(6):809-813.

Vural EM, van Munster BC, de Rooij SE. Optimal dosages for melatonin supplementation therapy in older adults: a systematic review of current literature. Drugs & aging. Jun 2014;31(6):441-451.

Wakatsuki T, Irisawa A, Imamura H, Terashima M, Shibukawa G, Takagi T, . . . Ohira H. Complete response of anaplastic pancreatic carcinoma to paclitaxel treatment selected by chemosensitivity testing. International journal of clinical oncology. 2010;15(3):310-313.

Walsh D, Kirkova J, Davis MP. The efficacy and tolerability of long-term use of dronabinol in cancer-related anorexia: a case series. Journal of pain and symptom management. Dec 2005;30(6):493-495.

Wang BL, Shen YM, Zhang QW, Li YL, Luo M, Liu Z, . . . Shi HS. Codelivery of curcumin and doxorubicin by MPEG-PCL results in improved efficacy of systemically administered chemotherapy in mice with lung cancer. International journal of nanomedicine. 2013;8:3521-3531.

Wang DY, Done SJ, Mc Cready DR, Leong WL. Validation of the prognostic gene portfolio, ClinicoMolecular Triad Classification using an independent prospective breast cancer cohort and external patient populations. Breast cancer research: BCR. Jul 4 2014;16(4):R71.

Wang H, Peng D, Xie J. Ginseng leaf-stem: bioactive constituents and pharmacological functions. Chinese medicine. 2009;4:20.

Wang P, Zhang S, Zhang XB, Li WJ, Hao XM, Zhang J. [Protective effect of dexrazoxane on cardiotoxicity in breast cancer patients who received anthracycline-containing chemotherapy]. Zhonghua Zhong Liu Za Zhi. 2013 Feb;35(2):135-9.

Wang Q, Yang W, Uytingco MS, Christakos S, Wieder R. 1,25-Dihydroxyvitamin D3 and all-trans-retinoic acid sensitize breast cancer cells to chemotherapy-induced cell death. Cancer Res. 2000 Apr 1;60(7):2040-8.

Wang WS, Lin JK, Lin TC, Chen WS, Jiang JK, Wang HS, . . . Chen PM. Oral glutamine is effective for preventing oxaliplatin-induced neuropathy in colorectal cancer patients. The oncologist. Mar 2007;12(3):312-319.

Wang X, Govind S, Sajankila SP, Mi L, Roy R, Chung FL. Phenethyl isothiocyanate sensitizes human cervical cancer cells to apoptosis induced by cisplatin. Molecular nutrition & food research. Oct 2011;55(10):1572-1581.

Wang YH, Yao N, Wei KK, Jiang L, Hanif S, Wang ZX, Pei CX. The efficacy and safety of probiotics for prevention of chemoradiotherapy-induced diarrhea in people with abdominal and pelvic cancer: a systematic review and meta-analysis. European journal of clinical nutrition. Nov 2016;70(11):1246-1253.

Wang YM, Jin BZ, Ai F, Duan CH, Lu YZ, Dong TF, Fu QL. The efficacy and safety of melatonin in concurrent chemotherapy or radiotherapy for solid tumors: a meta-analysis of randomized controlled trials. Cancer Chemother Pharmacol. May 2012;69(5):1213-1220.

Wang YY, Lin SX, Yang GQ, Liu HC, Sun DN, Wang YS. Clinical efficacy of CyberKnife combined with chemotherapy and hyperthermia for advanced non-small cell lung cancer. Molecular and clinical oncology. May 2013;1(3):527-530.

Wang Z, Chen JQ, Liu JL, Tian L. Exosomes in tumor microenvironment: novel transporters and biomarkers. J Transl Med. Oct 19 2016;14(1):297.

Weijl NI, Elsendoorn TJ, Lentjes EG, Hopman GD, Wipkink-Bakker A, Zwinderman AH, . . . Osanto S. Supplementation with antioxidant micronutrients and chemotherapy-induced toxicity in cancer patients treated with cisplatin-based chemotherapy: a randomised, double-blind, placebo-controlled study. European journal of cancer (Oxford, England: 1990). Jul 2004;40(11):1713-1723.

Weingart SN, Brown E, Bach PB, Eng K, Johnson SA, Kuzel TM, . . . Walters RS. NCCN Task Force Report. Journal of the National Comprehensive Cancer Network. Volume 6, Supplement 3. March 2008. <>.

Wesolowska O. Interaction of phenothiazines, stilbenes and flavonoids with multidrug resistance-associated transporters, P-glycoprotein and MRP1. Acta biochimica Polonica. 2011;58(4):433-448.

Wessner B, Strasser EM, Koitz N, Schmuckenschlager C, Unger-Manhart N, Roth E. Green tea polyphenol administration partly ameliorates chemotherapy-induced side effects in the small intestine of mice. J Nutr. 2007 Mar;137(3):634-40.

Widemann BC, Adamson PC. Understanding and Managing Methotrexate Nephrotoxicity. The Oncologist. June 1, 2006 2006;11(6):694-703.

Widemann BC, Schwartz S, Jayaprakash N, Christensen R, Pui CH, Chauhan N, Daugherty C, King TR, Rush JE, Howard SC. Efficacy of glucarpidase (carboxypeptidase g2) in patients with acute kidney injury after high-dose methotrexate therapy. Pharmacotherapy. 2014 May;34(5):427-39.

Wigmore PM, Mustafa S, El-Beltagy M, Lyons L, Umka J, Bennett G. Effects of 5-FU. Adv Exp Med Biol. 2010;678:157-64.

Wilken MK, Satiroff BA. Pilot study of "miracle fruit" to improve food palatability for patients receiving chemotherapy. Clin J Oncol Nurs. 2012 Oct;16(5):E173-7.

Wilson FP, Berns JS. Onco-nephrology: tumor lysis syndrome. Clin J Am Soc Nephrol. 2012 Oct;7(10):1730-9.

Winters M. Ancient medicine, modern use: Withania somnifera and its potential role in integrative oncology. Altern Med Rev. 2006 Dec;11(4):269-77.

Wolf S, Barton D, Kottschade L, Grothey A, Loprinzi C. Chemotherapy-induced peripheral neuropathy: prevention and treatment strategies. European journal of cancer (Oxford, England: 1990). Jul 2008;44(11):1507-1515.

Wong MY, Chiu GN. Liposome formulation of co-encapsulated vincristine and quercetin enhanced antitumor activity in a trastuzumab-insensitive breast tumor xenograft model. Nanomedicine: nanotechnology, biology, and medicine. Dec 2011;7(6):834-840.

Xian CJ. Roles of growth factors in chemotherapy-induced intestinal mucosal damage repair. Current pharmaceutical biotechnology. Aug 2003;4(4):260-269.

Xu JL, Xia R, Sun ZH, Sun L, Min X, Liu C, . . . Zhu YM. Effects of honey use on the management of radio/chemotherapy-induced mucositis: a meta-analysis of randomized controlled trials. International journal of oral and maxillofacial surgery. Dec 2016;45(12):1618-1625.

Xu X, Persson HL, Richardson DR. Molecular pharmacology of the interaction of anthracyclines with iron. Molecular pharmacology. Aug 2005;68(2):261-271.

Xu XT, Dai ZH, Xu Q, Qiao YQ, Gu Y, Nie F, Zhu MM, Tong JL, Ran ZH. Safety and efficacy of calcium and magnesium infusions in the chemoprevention of oxaliplatin-induced sensory neuropathy in gastrointestinal cancers. J Dig Dis. 2013 Jun;14(6):288-98.

Xue H, Sawyer MB, Wischmeyer PE, Baracos VE. Nutrition modulation of gastrointestinal toxicity related to cancer chemotherapy: from preclinical findings to clinical strategy. JPEN J Parenter Enteral Nutr. 2011 Jan;35(1):74-90.

Yamamoto D, Yamamoto C, Iwase S, Kuroda Y, Odagiri H, Nagumo Y. Efficacy of Vitamin E Treatment for Hand-Foot Syndrome in Patients Receiving Capecitabine. Breast Care (Basel). 2010;5(6):415-416.

Yan JJ, Shen F, Wang K, Wu MC. Patients with advanced primary hepatocellular carcinoma treated by melatonin and transcatheter arterial chemoembolization: a prospective study. Hepatobiliary Pancreat Dis Int. 2002;1(2):183-6.

Yardley DA. Drug Resistance and the Role of Combination Chemotherapy in Improving Patient Outcomes. International Journal of Breast Cancer. 2013;2013:15.

Yasueda A, Urushima H, Ito T. Efficacy and Interaction of Antioxidant Supplements as Adjuvant Therapy in Cancer Treatment: A Systematic Review. Integrative cancer therapies. Oct 26 2015.

Yeager CE, Olsen EA. Treatment of chemotherapy-induced alopecia. Dermatol Ther. 2011 Jul-Aug;24(4):432-42

Yeh CH, Moles R, Nicot C. Clinical significance of microRNAs in chronic and acute human leukemia. Molecular cancer. May 14 2016;15(1):37.

Yeh J, Kim BS, Peresie J. Protection against cisplatin-induced ovarian damage by the antioxidant sodium 2-mercaptoethanesulfonate (mesna) in female rats. Am J Obstet Gynecol. 2008 Apr;198(4):463.e1-6; discussion 463.e6-7.

Yekta ZP, Ebrahimi SM, Hosseini M, Nasrabadi AN, Sedighi S, Surmaghi MH, Madani H. Ginger as a miracle against chemotherapy-induced vomiting. Iran J Nurs Midwifery Res. 2012 Jul;17(5):325-9.

Yildirim I, Korkmaz A, Oter S, Ozcan A, Oztas E. Contribution of antioxidants to preventive effect of mesna in cyclophosphamide-induced hemorrhagic cystitis in rats. Cancer Chemother Pharmacol. 2004 Nov;54(5):469-73.

Yiu AJ, Yiu CY. Biomarkers in Colorectal Cancer. Anticancer research. Mar 2016;36(3):1093-1102.

Yoon YS, Kim JC. Recent applications of chemosensitivity tests for colorectal cancer treatment. World journal of gastroenterology: WJG. Nov 28 2014;20(44):16398-16408.

Yoshida T, Niho S, Toda M, Goto K, Yoh K, Umemura S, . . . Ohe Y. Protective effect of magnesium preloading on cisplatin-induced nephrotoxicity: a retrospective study. Japanese journal of clinical oncology. Apr 2014;44(4):346-354.

Yu CZ, Liu YP, Liu S, Yan M, Hu SJ, Song XJ. Systematic administration of B vitamins attenuates neuropathic hyperalgesia and reduces spinal neuron injury following temporary spinal cord ischaemia in rats. Eur J Pain. 2014 Jan;18(1):76-85.

Yu LL, Wu JG, Dai N, Yu HG, Si JM. Curcumin reverses chemoresistance of human gastric cancer cells by downregulating the NF-kappaB transcription factor. Oncology reports. 2011;26(5):1197-1203.

Yu M, Xue J, Li Y, Zhang W, Ma D, Liu L, Zhang Z. Resveratrol protects against arsenic trioxide-induced nephrotoxicity by facilitating arsenic metabolism and decreasing oxidative stress. Archives of toxicology. Jun 2013;87(6):1025-1035.

Yu Y, Ramena G, Elble RC. The role of cancer stem cells in relapse of solid tumors. Frontiers in bioscience (Elite edition). 2012;4:1528-1541.

Yuan Z, Wang H, Hu Z, Huang Y, Yao F, Sun S, Wu B. Quercetin Inhibits Proliferation and Drug Resistance in KB/VCR Oral Cancer Cells and Enhances Its Sensitivity to Vincristine. Nutrition and cancer. Jan 2015;67(1):126-136.

Yurekli Y, Unak P, Yenisey C, Ertay T, Biber Muftuler FZ, Medine EI. L-Carnitine Protection Against Cisplatin Nephrotoxicity In Rats: Comparison with Amifostin Using Quantitative Renal Tc 99m DMSA Uptake. Molecular imaging and radionuclide therapy. Apr 2011;20(1):1-6.

Zang J, Hou M, Gou HF, Qiu M, Wang J, Zhou XJ, . . . Yi C. Antiemetic activity of megestrol acetate in patients receiving chemotherapy. Supportive care in cancer: official journal of the Multinational Association of Supportive Care in Cancer. May 2011;19(5):667-673.

Zangemeister-Wittke U, Simon H-U. Myelosuppression. In: Schwab M, ed. Encyclopedia of Cancer. Berlin, Heidelberg: Springer Berlin Heidelberg; 2009:2008-2010.

Zarogoulidis P, Darwiche K, Sakkas A, Yarmus L, Huang H, Li Q, . . . Malecki M. Suicide Gene Therapy for Cancer - Current Strategies. Journal of genetic syndrome & gene therapy. 2013;4.

Zhang H, Yu T, Wen L, Wang H, Fei D, Jin C. Curcumin enhances the effectiveness of cisplatin by suppressing CD133 cancer stem cells in laryngeal carcinoma treatment. Experimental and therapeutic medicine. Nov 2013;6(5):1317-1321.

Zhang M, Li X, Lu X. [Metformin inhibits the proliferation of hypopharyngeal carcinoma Fadu cells and enhances the chemotherapeutic sensitivity of cells]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2014;49(4):317-22.

Zhang RX, Wu XJ, Wan DS, Lu ZH, Kong LH, Pan ZZ, Chen G. Celecoxib can prevent capecitabine-related hand-foot syndrome in stage II and III colorectal cancer patients: result of a single-center, prospective randomized phase III trial. Annals of oncology : official journal of the European Society for Medical Oncology / ESMO. May 2012;23(5):1348-1353.

Zhang S, Wang Y, Chen Z, Kim S, Iqbal S, Chi A, Ritenour C, Wang YA, Kucuk O, Wu D. Genistein enhances the efficacy of cabazitaxel chemotherapy in metastatic castration-resistant prostate cancer cells. Prostate. 2013;73(15):1681-9

Zhang XH, Wang L, Dong ZZ. [Study on zinc resistance to the immunosuppression caused by cyclophosphamidum in the mouse]. Sheng li xue bao: [Acta physiologica Sinica]. Oct 1992;44(5):528-532.

Zhang XX, Ma L, Wang JL, Wu WM, Feng LC, Huang DL. [Management of oral mucositis in patients with head and neck cancer receiving chemoradiotherapy and/or molecular targeted therapy]. Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery. Jun 2011;46(6):505-508.

Zhao D, Zhang W, Li XG, Wang XB, Zhang LF, Li M, . . . Wu LY. [Predicting clinical chemo-sensitivity of primary ovarian cancer using adenosine triphosphate-tumor chemosensitivity assay combined with detection of drug resistance genes]. Zhonghua fu chan ke za zhi. Mar 2011;46(3):193-198.

Zhao H, Zhang Q, Zhao L, Huang X, Wang J, Kang X. Spore Powder of Ganoderma lucidum Improves Cancer-Related Fatigue in Breast Cancer Patients Undergoing Endocrine Therapy: A Pilot Clinical Trial. Evidence-based complementary and alternative medicine: eCAM. 2012;2012:809614.

Zhao JL, Zhao J, Jiao HJ. Synergistic growth-suppressive effects of quercetin and cisplatin on HepG2 human hepatocellular carcinoma cells. Applied biochemistry and biotechnology. Jan 2014;172(2):784-791.

Zheng A, Moritani T. Influence of CoQ10 on autonomic nervous activity and energy metabolism during exercise in healthy subjects. J Nutr Sci Vitaminol (Tokyo). 2008 Aug;54(4):286-90.

Zheng J, Lee HC, Bin Sattar MM, Huang Y, Bian JS. Cardioprotective effects of epigallocatechin-3-gallate against doxorubicin-induced cardiomyocyte injury. European journal of pharmacology. Feb 10 2011;652(1-3):82-88.

Zhou QM, Chen QL, Du J, Wang XF, Lu YY, Zhang H, Su SB. Synergistic effect of combinatorial treatment with curcumin and mitomycin C on the induction of apoptosis of breast cancer cells: a cDNA microarray analysis. International journal of molecular sciences. 2014;15(9):16284-16301.

Zhou QM, Wang XF, Liu XJ, Zhang H, Lu YY, Huang S, Su SB. Curcumin improves MMC-based chemotherapy by simultaneously sensitising cancer cells to MMC and reducing MMC-associated side-effects. European journal of cancer (Oxford, England: 1990). Sep 2011;47(14):2240-2247.

Zhou QM, Wang XF, Liu XJ, Zhang H, Lu YY, Su SB. Curcumin enhanced antiproliferative effect of mitomycin C in human breast cancer MCF-7 cells in vitro and in vivo. Acta pharmacologica Sinica. Nov 2011;32(11):1402-1410.

Zhou QM, Zhang H, Lu YY, Wang XF, Su SB. Curcumin reduced the side effects of mitomycin C by inhibiting GRP58-mediated DNA cross-linking in MCF-7 breast cancer xenografts. Cancer science. Nov 2009;100(11):2040-2045.

Zhu BD, Li X, Zhao QC, Huang XL. [Enhancement of antioxidant capability of cancer patients during chemotherapy by reduced glutathione]. Ai zheng = Aizheng = Chinese journal of cancer. Apr 2004;23(4):452-455.

Zou YH, Liu XM. [Effect of astragalus injection combined with chemotherapy on quality of life in patients with advanced non-small cell lung cancer]. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2003 Oct;23(10):733-735.

Zysset-Burri DC, Bellac CL, Leib SL, Wittwer M. Vitamin B6 reduces hippocampal apoptosis in experimental pneumococcal meningitis. BMC infectious diseases. 2013;13:393.