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Estradiol (E2) is the predominant sex hormone present in females and is also found at lower levels in men. It represents the major estrogen in humans. Estradiol not only impacts reproductive and sexual functioning, but also affects other systems including bone health, heart health, nerves, and metabolism.
E2 is the most active of all three estrogens commonly measured in a clinical setting. For women, it is important to compare the relationship between estradiol and progesterone in evaluating menopausal symptoms such as hot flashes, mood disorders, and aging skin.
In men, high levels of estradiol are associated with abdominal fat, enlargement of the prostate, and cardiovascular risk. In both men and women, low levels of estradiol are associated with osteoporosis.
Fasting is not required for this test. Take all medications as prescribed. If you are supplementing with any hormones, we suggest taking them approximately 2 hours prior to having your blood drawn to see peak levels. Hormones are best drawn between 8-10 AM. Hormonal contraceptives can interfere with progesterone and estrogen results.
Pre-menopausal women: For a 28 day cycle, blood should be drawn on day 21 (day 1 is the day that bleeding begins). For longer or shorter cycles, count 8 days back from the day your next menstruation would start.
Post-menopausal women: Blood can be drawn any day of the month.
The laboratory services are for informational purposes only. It is not the intention of National Diagnostics, Inc and Life Extension to provide specific medical advice but rather to provide users with information to better understand their health. Specific medical advice including diagnosis and treatment will not be provided. Always seek the advice of a trained health professional for medical advice, diagnosis or treatment.
Both the physician and the testing laboratory are independent contractors with whom National Diagnostics, Inc makes arrangements for your blood tests. Neither National Diagnostics, Inc or Life Extension will be liable for any acts or omissions of the physician, the testing laboratory, or their agents or employees.
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