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An Innovative New Treatment for Migraine

September 2004

By Dr. Sergey A. Dzugan


Analysis of the medical literature and our own experience convince us that migraine is a complex disorder that comprises malfunctions in several systems: the neurohormonal system, which includes a feedback loop mechanism between the hypothalamus, pituitary gland, and glands that produce steroid hormones; the sympathetic-parasympathetic nervous systems; the calcium-magnesium ion system; the pineal gland; and the digestive system. All these systems and changes within them are closely interrelated, and each can be a trigger mechanism for migraine. Contradictory results with other migraine treatments—for example, using medications that modulate serotonin—offer additional evidence that the problem is not high or low sympathetic nervous system activity, but rather an imbalance between the sympathetic and parasympathetic nervous systems.

Following this logic, the basic method of migraine treatment must be directed toward restoring integrity between these different systems. In our hands, the simultaneous restoration of neurohormonal and metabolic integrity was an effective approach to the successful management of migraine.


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