Life Extension Magazine®

The New Life Extension Mix™ Formula

The Life Extension Mix formula is upgraded on an annual basis to provide members with the most advanced health-promoting nutrients. The new Life Extension Mix contains more vitamin D and provides a novel nutrient that helps reduce undesirable glycation reactions.

Scientifically reviewed by: Dr. Gary Gonzalez, MD, on January 2021.

The New Life Extension Mix™ Formula

Published scientific studies document that people who eat the most fruits and vegetables have much lower incidences of health problems. Few people, however, consistently eat enough plant foods to protect against common age-related decline,1-3 and commercial multivitamins do not provide all of the vital plant components needed to maintain good health.

In addition to providing the world's broadest spectrum of plant extracts, Life Extension Mix has been upgraded to include pyridoxamine, an extremely potent form of vitamin B6. Pyridoxamine helps block the formation of advanced glycation end (AGE) products, enhances glucose metabolism and consumes toxic free radicals. It is considered to be one of the most effective anti-glycating nutrients.

The new Life Extension Mix also includes more vitamin D3. During the Super Sale, the full dose of Life Extension Mix can be obtained for as little as $1.34 per day.

9 tablets, 14 capsules, or three scoops of powder provide:

Vegetable-Fruit Complex

Green tea extract (decaf.) (98% polyphenols/45% EGCG)

325 mg

Broccoli sprout concentrate (providing Sulforaphane, glucosinolates, D-3T, and PEITC)

525 mg

Olive juice extract (fresh fruit) [6% hydroxytyrosol (0.75 mg), 3% oleuropein (0.38 mg)]

12.5 mg

Grapeseed extract (Leucoselect®) (95% proanthocyanidins)

25 mg

Grape extract (BioVin®)(95% proanthocyanidins/75% polyphenols/200 ppm trans-resveratrol)

25 mg

Ginger extract (5% gingerols)

200 mg

Luteolin (Pureolin™)

8 mg

Alpha carotene

100 IU

Lycopene (tomato extract)

3 mg

Lutein complex (marigold) (15 mg lutein/465 mcg zeaxanthin)

33.3 mg

Milk thistle extract (85% silymarin)

100 mg


15 mg

Calcium D-Glucarate

200 mg

Citrus Bioflavonoids (70 mg hesperidin/30 mg other flavonones/phenolinic compounds)

200 mg

Acerola juice powder

300 mg

Bilberry (25% anthocyanidins)

30 mg

Pomegranate (30% punicalagins)

85 mg

Sesame seed lignan extract

10 mg

Berry-fruit blend (blackberry, blueberry, cranberry, elderberry, persimmon, plum, and cherry)

200 mg

Wild Blueberry extract (VitaBlue®) (14% total phenolics/4.9% anthocyanins/660 ppm pterostilbene)

150 mg

Cocoa Extract (CocoaGold™)(45% polyphenols/30 mg standardized cocoa polyphenols)

67 mg


Water-Soluble Vitamins and Enzymatic Activators

Vitamin C (as calcium ascorbate, ascorbic acid, ascorbyl palmitate, magnesium ascorbate, niacinamide ascorbate, and acerola juice powder)

2000 mg

Folic acid

800 mcg


3000 mcg

Trimethylglycine (TMG)

100 mg

Vitamin B1 (thiamine HCl)

125 mg

Vitamin B2 (riboflavin)

50 mg

Supplying: Riboflavin 5-phosphate

2 mg

Vitamin B3 (niacinamide and niacinamide ascorbate)

117 mg

Vitamin B3 (niacin)

73 mg

Vitamin B5 (D-calcium pantothenate)

600 mg


5 mg

Vitamin B6 (pyridoxine HCl)

100 mg

Pyridoxamine (pyridoxamine DiHCl)

50 mg

Pyridoxal 5-phosphate

2.5 mg

Vitamin B12 (cyanocobalamin)

250 mcg

Vitamin B12 (hydroxylcobalamin)

250 mcg

Vitamin B12 (ion exchange resin)

100 mcg

PABA (para-aminobenzoic acid)

200 mg


Fat-Soluble Vitamins

Vitamin A (acetate)

2300 IU

Beta-carotene (natural D. Salina)

2700 IU

Vitamin D3 (cholecalciferol)

1000 IU

Ascorbyl palmitate (fat-soluble vitamin C)

250 mg

Vitamin E (natural D-alpha tocopheryl succinate)

400 IU


Amino Acid Complex


600 mg


200 mg


Mineral Complex

Selenium (from se-methylselenocysteine)

100 mcg

Selenium (from L-selenomethionine—SelenoPure®)

50 mcg

Selenium (from sodium selenate)

50 mcg

Zinc (methionate) (OptiZinc®)

20 mg

Zinc (succinate)

15 mg

Boron (as boron citrate/aspartate/glycinate)

3 mg


218 mg

Copper (as copper bisglycinate chelate)

1 mg

Chromium (as Chromium 454™ bio-organic yeast extract matrix)

500 mcg

Potassium chloride (37.4 mg elemental)

71.3 mg

Molybdenum (sodium molybdate)

125 mcg

Manganese (gluconate)

1 mg

Iodine (potassium iodide)

75 mcg

Magnesium oxide (335.96 mg elemental)

560 mg

Magnesium citrate (35.28 mg elemental)

261.3 mg

Magnesium glycinate (11.74 mg elemental)

100 mg

Magnesium taurinate (7.83 mg elemental)

100 mg

Magnesium arginate (5.87 mg elemental)

100 mg

Magnesium ascorbate (3.40 mg elemental)

58.1 mg


Cholinergic Complex

Choline (as choline bitartrate)

120 mg

Phosphatidylcholine (from soy)

150 mg


250 mg


The niacin in the high niacin version of this product may cause flushing (a feeling of warmth and reddening of the skin). This effect is temporary and harmless. Periodic liver function testing and supervision of a qualified healthcare professional are strongly recommended with niacin dosing in excess of 500 mg daily. Life Extension Mix should not be used by individuals who have an allergy to sesame. Those with Wilson's disease or cancer patients on a physician-supervised copper depletion therapy should avoid copper. Life Extension Mix is available without cooper.

• Betatene® is a registered trademark of Cognis Nutrition and Health. • The use of Calcium D-Glucarate is licensed from Applied Food Sciences, LLC under U.S. Patent No. 4,845,123. • OptiZinc® is a registered trademark of InterHealth Nutritionals, Inc. • SelenoPure® is a registered trademark of Nutrition 21. • Chromium 454™ is a trademark of VDF Futureceuticals, Inc. • VitaBlue® is a registered trademark of VDF FutureCeuticals, Inc. • Leucoselect® is a registered trademark of Indena S.p.A. • BioVin® is a registered trademark of Cyvex Nutrition. • PureolinTM is a trademark of Pharma Science Nutrients, Inc., and is used here under license. All rights reserved worldwide. • Lyc-O-Mato® is a registered trademark of LycoRed Natural Products Limited. • Pomella® is a registered trademark of Verdure Sciences, Inc.

  1. Stroke. 2004 Sep;35(9)2014-9.
  2. Mutant Res. 1999 Jul 16;428(1-2):329-38.
  3. J Am Diet Assoc. 1996 Oct;96(10):1027-39.

To order during Super Sale, call toll-free 1-800-544-4440.

Green tea extract

Scientists have identified multiple mechanisms by which green tea extract helps protect against LDL oxidation, neuronal oxidation, and a host of other structural and functional age-related changes. LIFE EXTENSION MIX™ provides more green tea extract than found in commercial formulations.


Broccoli is one of the vegetables best documented to protect healthy DNA. The broccoli concentrate in LIFE EXTENSION MIX™ is standardized to provide sulforaphane and glucosinolates, two compounds attributed to broccoli's protective benefits.

Olive juice extract

Olive polyphenols help protect against LDL oxidation, suppress free radicals, and stabilize cell membranes. LIFE EXTENSION MIX™ contains an olive extract standardized to provide the best-documented polyphenol called hydroxytyrosol.


Luteolin is a flavonoid found in parsley, artichoke, basil, celery, and other foods. It has shown the ability to help protect against DNA oxidative damage. When measured against 27 other citrus flavonoids, luteolin showed the second-most beneficial effect at maintaining healthy DNA. Luteolin also suppresses excess levels of interleukin-6 and interleukin-1b. LIFE EXTENSION MIX™ contains a standardized dose of 8 mg of luteolin.


Lycopene is the red carotenoid in tomatoes that supports a healthy prostate and helps promote healthy lipid profiles for those already within a normal range.


Lutein is found in spinach and collard greens and has been shown to help maintain eye macula pigment structure. LIFE EXTENSION MIX™ contains 60 times more lutein than does Centrum®.

Calcium D-Glucarate

D-glucarate is found in grapefruit, apples, oranges, broccoli, and Brussels sprouts. D-glucarate supports a detoxification process that helps to remove DNA toxins.


Pomegranate may be the most effective plant to help maintain optimal endothelial function. This pomegranate extract standardized to provide the punicalagins and other polyphenols found in up to 2.6 ounces of pomegranate juice.

Sesame lignans extract

Sesame lignans increase tissue levels of vitamin E and gamma tocopherol, and inhibit the formation of an inflammatory precursor called arachidonic acid.

Wild Blueberry extract

Wild blueberry extract, concentrated and standardized to help maintain optimal neuronal function.

Cocoa extract

Cocoa polyphenols offer the cardiovascular benefits of cocoa without fat or calories and contain the same amount of polyphenols as a 1/4 serving (about 0.5 ounces) of a dark chocolate bar

Pyridoxamine and Pyridoxal 5-phosphate

Pyridoxamine and Pyridoxal 5-phosphate help protect against glycation reactions, a toxic process in which sugars bind to proteins to form non-functional structures in the body.

Vitamin D3

Potent amounts of vitamin D3 are included to further help maintain healthy bone density and protect healthy DNA.

Vitamin E

LIFE EXTENSION MIX™ contains only the expensive dry powder form of vitamin E. This natural form of vitamin E (succinate) has been shown to promote healthy DNA better than other forms.

N-acetyl-L-cysteine and Taurine

N-acetyl-L-cysteine suppresses free radicals inside the cells and maintains healthy glutathione levels. Taurine may protect against free radicals between cells and supports eye health.


Some scientific evidence suggests that consumption of selenium may reduce the risk of certain forms of cancer; however, the FDA has determined that this evidence is limited and not conclusive.


Zinc is often poorly absorbed, but LIFE EXTENSION MIX™ provides two of the most bioavailable forms of zinc.


Boron is not only needed to maintain healthy bone density but may also help promote healthy prostate cell development.


LIFE EXTENSION MIX™ provides a high amount of chromium to help maintain arterial wall structure and already normal glucose levels.


Magnesium helps protect arteries and heart valves, and supports heart and brain cells. LIFE EXTENSION MIX™ provides high potencies of six different forms of magnesium to fully saturate the body with this lifesaving mineral.

Choline and Phosphatidylcholine

Maintaining high levels of acetylcholine in the brain helps support cognitive function and memory.