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Study finds association between lignan and stilbene intake and improvements in cognitive function

Health & Medicine Daily

2020 OCT 20 (NewsRx) -- By a News Reporter-Staff News Editor at Health & Medicine Daily -- Investigators publish new report on Health and Medicine - Diet and Nutrition. According to news reporting from Pamplona, Spain, by NewsRx journalists, research stated, “The global growing rates of cognitive decline and dementia, together with the absence of curative therapies for these conditions, support the interest in researching potential primary prevention interventions, with particular focus on dietary habits. The aim was to assess the association between the intake of polyphenols and 6-year change in cognitive function in the ‘Seguimiento Universidad de Navarra’ (SUN) Project, a Spanish prospective cohort study.”

The news correspondents obtained a quote from the research from Navarra Institute for Health Research, “Changes (final -initial) in cognitive function were evaluated in a subsample of 806 participants (mean age 66 years (SD 5), 69.7% male) of the SUN Project using the validated Spanish Telephone Interview for Cognitive Status-modified (STICS-m) score. Polyphenol intake was derived from a validated semi-quantitative food-frequency questionnaire and matching food composition data from the Phenol Explorer database. Multivariable linear regression models were used to evaluate the association between total polyphenol intake, polyphenol subclasses and cognitive changes. No significant association between total polyphenol intake and changes in cognitive function was found. However, a higher intake of lignans (bQuintile (Q) 5 vs. Q1 0.81; 95% CI 0.12, 1.51; p trend=0.020) and stilbenes (bQ5 vs. Q1 0.82; 95% CI 0.15, 1.49; p trend 0.028) was associated with more favorable changes in cognitive function over time, particularly with respect to immediate memory and language domains. Olive oil and nuts were the major sources of variability in lignan intake; and wine in stilbene intake.”

According to the news reporters, the research concluded: “The results suggest that lignan and stilbene intake was associated with improvements in cognitive function.”

This research has been peer-reviewed.

For more information on this research see: Polyphenol intake and cognitive decline in the Seguimiento Universidad de Navarra (SUN) Project. British Journal of Nutrition, 2020;():1-24. British Journal of Nutrition can be contacted at: Cambridge University Press, 32 Avenue of the Americas, New York, NY 10013-2473. (Cambridge University Press - www.cambridge.org; British Journal of Nutrition - http://journals.cambridge.org/action/displayJournal?jid=BJN)

Our news journalists report that additional information may be obtained by contacting Marta Fernandez-Matarrubia, IdiSNA, Navarra Institute for Health Research, Pamplona, Spain. Additional authors for this research include Leticia Goni, Andrea Romanos-Nanclares, Cristina Razquin, Miguel Ruiz-Canela, Miguel A. Martinez-Gonzalez and Estefania Toledo.

The direct object identifier (DOI) for that additional information is: https://doi.org/10.1017/s000711452000392x. This DOI is a link to an online electronic document that is either free or for purchase, and can be your direct source for a journal article and its citation.

Publisher contact information for the British Journal of Nutrition is: Cambridge University Press, 32 Avenue of the Americas, New York, NY 10013-2473.

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