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Orally administered cinnamon extract attenuates cognitive and neuronal deficits following traumatic brain injury

Middle East Daily

2020 SEP 21 (NewsRx) -- By a News Reporter-Staff News Editor at Middle East Daily -- Investigators publish new report on Central Nervous System Diseases and Conditions - Traumatic Brain Injury. According to news reporting from Tel Aviv, Israel, by NewsRx journalists, research stated, “The present paper shows how cinnamon extract (CE) consumption mitigates neuronal loss and memory impairment following traumatic brain injury (TBI), one of the world’s most common neurodegenerative diseases. TBI patients suffer short-and long-term behavioral, cognitive, and emotional impairments, including difficulties in concentration, memory loss, and depression.”

Financial support for this research came from Tel Aviv University.

The news correspondents obtained a quote from the research from the Tel Aviv University - New York State Sackler School of Medicine, “Research shows that CE application can mitigate cognitive and behavioral impairments in animal models for Alzheimer’s and Parkinson’s disease, whose pathophysiology is similar to that of TBI. This study builds on prior research by showing similar results in TBI mice models. After drinking CE for a week, mice were injured using our 70-g weight drop TBI device. For 2 weeks thereafter, the mice continued drinking CE alongside standard lab nutrition. Subsequently, the mice underwent behavioral tests to assess their memory, motor activity, and anxiety. The mice brains were harvested for immunohistochemistry staining to evaluate overall neuronal survival. Our results show that CE consumption almost completely mitigates memory impairment and decreases neuronal loss after TBI. Mice that did not consume CE demonstrated impaired memory. Our results also show that CE consumption attenuated neuronal loss in the temporal cortex and the dentate gyrus. Mice that did not consume CE suffered a significant neuronal loss. There were no significant differences in anxiety levels and motor activity between all groups.”

According to the news reporters, the research concluded: “These findings show a new therapeutic approach to improve cognitive function and decrease memory loss after TBI.”

For more information on this research see: Orally Administered Cinnamon Extract Attenuates Cognitive and Neuronal Deficits Following Traumatic Brain Injury. Journal of Molecular Neuroscience, 2020;():. Journal of Molecular Neuroscience can be contacted at: Springer, 233 Spring Street, New York, NY 10013, USA. (Springer - www.springer.com; Journal of Molecular Neuroscience - http://www.springerlink.com/content/0895-8696/)

Our news journalists report that additional information may be obtained by contacting Vardit Rubovitch, Dept. of Anatomy and Anthropology, Tel Aviv University - New York State Sackler School of Medicine, Tel Aviv University, Tel-Aviv, Israel. Additional authors for this research include Doaa Qubty, Tali Benromano, Michael Ovadia and Chaim G. Pick.

The direct object identifier (DOI) for that additional information is: https://doi.org/10.1007/s12031-020-01688-4. This DOI is a link to an online electronic document that is either free or for purchase, and can be your direct source for a journal article and its citation.

Publisher contact information for the Journal of Molecular Neuroscience is: Springer, 233 Spring Street, New York, NY 10013, USA.

(Our reports deliver fact-based news of research and discoveries from around the world.)