Studies from L.E. Simental-Mendia et al Provide New Data on Vitamin E Deficiency (Vitamin E Deficiency and Oxidative Status are Associated with...
Health & Medicine Week
Our news editors obtained a quote from the research, "Apparently healthy men and women aged 18-65 years were enrolled in a case control study. Individuals with new diagnosis of prediabetes were considered as cases and compared with a control group of individuals with normal glucose tolerance. Smoking, alcohol intake, pregnancy, diabetes, kidney disease, liver disease, cardiovascular disease, malignancy, glucocorticoid treatment and consumption of lipid-lowering drugs, antioxidants and vitamin supplements were exclusion criteria. Vitamin E deficiency was defined by serum levels of alpha-tocopherol < 11.6 mu mol/L, oxidative status was assessed by total antioxidant capacity and lipid peroxidation, and prediabetes was considered by the presence of impaired fasting glucose and/or impaired glucose tolerance. A total of 148 subjects were allocated into the case (n = 74) and control (n = 74) groups. The frequency of vitamin E deficiency was higher in the case group (41.8%) compared with the control group (35.1%), p = 0.03. The logistic regression analysis adjusted by age, waist circumference and body mass index, revealed a significant association between vitamin E deficiency (OR 3.23; 95% CI: 1.34-7.79, p = 0.009), lipoperoxidation (OR 2.82; CI 95%: 1.42-5.59, p = 0.003) and total antioxidant capacity (OR 0.93; CI 95%: 0.90-0.96, p< 0.001) with prediabetes."
According to the news editors, the research concluded: "Results of the present study suggest that both vitamin E deficiency and oxidative status are associated with prediabetes in apparently healthy subjects."
For more information on this research see: Vitamin E Deficiency and Oxidative Status are Associated with Prediabetes in Apparently Healthy Subjects. Archives of
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The direct object identifier (DOI) for that additional information is: https://doi.org/10.1016/j.arcmed.2017.03.018. This DOI is a link to an online electronic document that is either free or for purchase, and can be your direct source for a journal article and its citation.
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