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Investigators at Faculty of Medicine Have Reported New Data on Vitamin D Deficiency (Association between vitamin D deficiency and lipid and non-lipid markers of cardiovascular diseases in the middle east region)

NewsRx Women’s Health Daily

06-24-19

2019 JUN 21 (NewsRx) -- By a News Reporter-Staff News Editor at NewsRx Women’s Health Daily -- Current study results on Nutritional and Metabolic Diseases and Conditions - Vitamin D Deficiency have been published. According to news reporting out of Beirut, Lebanon, by NewsRx editors, research stated, “Previous studies have associated vitamin D deficiency with cardiovascular disease (CVD) markers. The underlying mechanism remains elusive.”

Our news journalists obtained a quote from the research from the Faculty of Medicine, “Lipid and non-lipid markers of CVD and their relationship to vitamin D deficiency have not been assessed simultaneously. To measure the association between vitamin D deficiency and non-lipid markers of CVD after adjustment of lipid markers. This cross-sectional study used the following biological data, which was routinely collected in a general hospital laboratory database between 2011 and 2016: 25OH vitamin D [25(OH)D], creatinine, CKD-EPI eGFR (eGFR), fasting blood glucose (FPG), glycated hemoglobin (HbA1c), uric acid, g-glutamyl transferase (gGT), C-reactive protein (CRP), total cholesterol, LDL cholesterol, HDL cholesterol, triglycerides, and a surrogate for CVD. Crude odds ratios (ORs) and ORs adjusted for lipid profile, gender and age using separate logistic regression models were derived. A total of 8658 subjects were included. Half had 25(OH)D <20 ng/mL. 25(OH)D was associated with increased odds of CRP, eGFR, increased uric acid, gGT, FPG, HbA1c, male gender, CV status, and abnormal lipid markers. After adjustment for lipid markers, age, and gender, vitamin D deficiency was associated with increased odds of CRP, eGFR, gGT, FPG, HbA1c, and the surrogate for CVD. In this exploratory analysis, the first of its kind in the MENA region, vitamin D deficiency was associated with abnormal lipid markers, non-lipid markers of CVD, male gender, lower eGFR, and a surrogate variable for CVD.”

According to the news editors, the research concluded: “The association between vitamin D deficiency and non-lipid markers of CVD persisted after adjustment for lipid markers, age, and gender.”

For more information on this research see: Association between vitamin D deficiency and lipid and non-lipid markers of cardiovascular diseases in the middle east region. European Journal of Clinical Nutrition, 2018;73(6):850-858. European Journal of Clinical Nutrition can be contacted at: Nature Publishing Group, 345 Park Avenue South, New York, NY 10010-1707, USA. (Nature Publishing Group - http://www.nature.com/; European Journal of Clinical Nutrition - http://www.nature.com/ejcn/)

Our news journalists report that additional information may be obtained by contacting N. Fares, Laboratoire de recherche en Physiologie et Physiopathologie (LRPP), pole technologie sante, Faculty of Medicine, Universite Saint Joseph, Beirut, Lebanon. Additional authors for this research include G. Sleilaty, S. El Samad, Y. Saliba, R. Chahine and N. Fares.

The direct object identifier (DOI) for that additional information is: https://doi.org/10.1038/s41430-018-0280-1. This DOI is a link to an online electronic document that is either free or for purchase, and can be your direct source for a journal article and its citation.

Publisher contact information for the European Journal of Clinical Nutrition is: Nature Publishing Group, 345 Park Avenue South, New York, NY 10010-1707, USA.

(Our reports deliver fact-based news of research and discoveries from around the world.)

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